K05070                      KO                                     
IL2RG, CD132
interleukin 2 receptor gamma
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
map05340  Primary immunodeficiency
H00091  T-B+Severe combined immunodeficiency
H00093  Combined immunodeficiency
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04151 PI3K-Akt signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04659 Th17 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05162 Measles
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05340 Primary immunodeficiency
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04090 CD molecules
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05070  IL2RG, CD132; interleukin 2 receptor gamma
CD molecules [BR:ko04090]
  K05070  CD132, IL2RG; interleukin 2 receptor, gamma (severe combined immunodeficiency)
Other DBs
GO: 0004911
HSA: 3561(IL2RG)
PTR: 101059843(IL2RG)
PPS: 100986679(IL2RG)
PON: 100454903(IL2RG)
NLE: 100585758(IL2RG)
MCC: 641338(IL2RG)
MCF: 102144912(IL2RG)
MTHB: 126946182
CSAB: 103232148(IL2RG)
CATY: 105586122(IL2RG)
PANU: 101008968(IL2RG)
TGE: 112615453(IL2RG)
RRO: 104656782(IL2RG)
RBB: 108532108(IL2RG)
TFN: 117077624(IL2RG)
PTEH: 111533635(IL2RG)
CJC: 100388189(IL2RG)
SBQ: 101047979(IL2RG)
CSYR: 103250262(IL2RG)
MMUR: 105855320(IL2RG)
LCAT: 123628744(IL2RG)
OGA: 100961176(IL2RG)
MMU: 16186(Il2rg)
MCAL: 110286942(Il2rg)
MPAH: 110313918(Il2rg)
RNO: 140924(Il2rg)
MCOC: 116087170(Il2rg)
MUN: 110564656(Il2rg)
CGE: 100756284(Il2rg)
MAUA: 101824015(Il2rg)
PLEU: 114708654(Il2rg)
MFOT: 126487061
AAMP: 119804964(Il2rg)
NGI: 103751955(Il2rg)
HGL: 101715243(Il2rg)
CPOC: 100713379(Il2rg)
CCAN: 109673990(Il2rg)
DORD: 105997296(Il2rg)
DSP: 122120620(Il2rg)
NCAR: 124972015
OCU: 103351862(IL2RG)
OPI: 101536616(IL2RG)
TUP: 102476004(IL2RG)
CFA: 403851(IL2RG)
CLUD: 112671816(IL2RG)
VVP: 112907637(IL2RG)
VLG: 121483086(IL2RG)
AML: 100468126(IL2RG)
UMR: 103682591(IL2RG)
UAH: 113245610(IL2RG)
ELK: 111161041
LLV: 125092325
MPUF: 101678968(IL2RG)
ORO: 101374379(IL2RG)
ZCA: 113930805(IL2RG)
MLX: 118025926(IL2RG)
NSU: 110572174(IL2RG)
FCA: 101090239(IL2RG)
PYU: 121025256(IL2RG)
PBG: 122477318(IL2RG)
LRUF: 124521570
PTG: 102966580(IL2RG)
PPAD: 109254610(IL2RG)
AJU: 106982399(IL2RG)
HHV: 120246070(IL2RG)
BTA: 281862(IL2RG)
BOM: 102266681(IL2RG)
BIU: 109555190(IL2RG)
BBUB: 102402566(IL2RG)
CHX: 102169656(IL2RG)
OAS: 101103538(IL2RG)
ODA: 120882006(IL2RG)
CCAD: 122434652(IL2RG)
SSC: 397156(IL2RG)
CBAI: 105083690(IL2RG)
CDK: 105087982(IL2RG)
VPC: 102526609(IL2RG)
BACU: 103016442(IL2RG)
LVE: 103087530(IL2RG)
OOR: 101286718(IL2RG)
DLE: 111167807(IL2RG)
PCAD: 102979617(IL2RG)
PSIU: 116747462(IL2RG)
ECB: 100055911(IL2RG)
EPZ: 103544610(IL2RG)
EAI: 106828880(IL2RG)
MYB: 102241164(IL2RG)
MYD: 102757155(IL2RG)
MMYO: 118654549(IL2RG) 118661694(METTL8)
MLF: 102441989(IL2RG)
MNA: 107532895(IL2RG)
PKL: 118704153(IL2RG) 118709172(METTL8)
HAI: 109385585(IL2RG)
DRO: 112300079(IL2RG)
AJM: 119035395(IL2RG)
PDIC: 114504996(IL2RG)
PHAS: 123824325(IL2RG)
MMF: 118635917(IL2RG)
RFQ: 117024055(IL2RG)
PALE: 102888070(IL2RG)
PGIG: 120585387(IL2RG)
PVP: 105299605(IL2RG)
RAY: 107513773(IL2RG)
MJV: 108403309(IL2RG)
TOD: 119246676(IL2RG)
SARA: 101545374(IL2RG)
LAV: 100664834(IL2RG)
TMU: 101359472
DNM: 101437298(IL2RG)
MDO: 100619507(IL2RG)
GAS: 123254760(IL2RG)
SHR: 100929781(IL2RG)
PCW: 110201024(IL2RG)
OAA: 114812802(IL2RG)
GGA: 395199(IL2RG)
PCOC: 116229598(IL2RG)
MGP: 104912104(IL2RG)
CJO: 107312576(IL2RG)
NMEL: 110403135(IL2RG)
APLA: 101794194(IL2RG)
ACYG: 106037383(IL2RG)
AFUL: 116494466(IL2RG)
TGU: 100226174(IL2RG)
LSR: 110472683(IL2RG)
SCAN: 103824248(IL2RG)
PMOA: 120506133(IL2RG)
OTC: 121331697(IL2RG)
PRUF: 121363036(IL2RG)
GFR: 102043888(IL2RG)
FAB: 107603321(IL2RG)
PHI: 102112500(IL2RG)
PMAJ: 107203656(IL2RG)
CCAE: 111929372(IL2RG)
CCW: 104691748(IL2RG)
CBRC: 103617890(IL2RG)
ETL: 114067449(IL2RG)
ZAB: 102065939(IL2RG)
ACHL: 103797625(IL2RG)
FPG: 101923008(IL2RG)
FCH: 102052025(IL2RG)
CLV: 102094834(IL2RG)
EGZ: 104124289(IL2RG)
NNI: 104012899(IL2RG)
PLET: 104628689(IL2RG)
PCRI: 104037364
ACUN: 113479902(IL2RG)
TALA: 104369148(IL2RG)
PADL: 103923348(IL2RG)
AFOR: 103905836(IL2RG)
ACHC: 115333600(IL2RG)
HALD: 104315844(IL2RG)
CCRI: 104169538
CSTI: 104563317(IL2RG)
CMAC: 104487058
MUI: 104533161(IL2RG)
FGA: 104081348(IL2RG)
LDI: 104339820
MNB: 103770051
OHA: 104335752(IL2RG)
NNT: 104412205
DPUB: 104296345(IL2RG)
PGUU: 104470831
ACAR: 104522005
AVIT: 104267159
CVF: 104283545(IL2RG)
AROW: 112966349(IL2RG)
NPD: 112948661(IL2RG)
DNE: 112989719(IL2RG)
ASN: 102379602(IL2RG)
AMJ: 102575498(IL2RG)
GGN: 109300562(IL2RG)
PSS: 102443813(IL2RG)
CMY: 102933244(IL2RG)
CPIC: 101931356(IL2RG)
TST: 117883178(IL2RG)
CABI: 116833382(IL2RG)
MRV: 120372096(IL2RG)
ACS: 103281066(il2rg)
PVT: 110080214(IL2RG)
SUND: 121937400(IL2RG)
PBI: 103061889(IL2RG)
PMUR: 107303211(IL2RG)
PGUT: 117679627(IL2RG)
VKO: 123034956(IL2RG)
PMUA: 114589433(IL2RG)
ZVI: 118078798(IL2RG)
GJA: 107108490(IL2RG)
STOW: 125442884(IL2RG)
XLA: 100036958(il2rg.L)
XTR: 100492995(il2rg)
NPR: 108800627(IL2RG)
RTEM: 120921918(IL2RG)
BBUF: 120977619(IL2RG)
BGAR: 122919489(IL2RG)
DRE: 100144554(il2rgb) 796604(il2rga)
PPRM: 120475010(il2rgb) 120482795(il2rga)
MAMB: 125259092(il2rgb) 125262226 125262227(il2rga)
IPU: 108269358(il2rgb) 108276805(il2rga)
SMEO: 124385987(il2rgb) 124393103(il2rga)
TFD: 113636124(il2rgb) 113650230(il2rga)
TRU: 100190946(il2rg)
LCO: 104938889
NCC: 104967331
CGOB: 115018623
SLUC: 116037024
ECRA: 117956151
ESP: 116699939(il2rg)
GAT: 120821796
PPUG: 119215172
MSAM: 119894956
CUD: 121518414
OLA: 101156347
OML: 112138762
XMA: 102230559
XCO: 114152754
XHE: 116728980
PRET: 103475386
PLAI: 106958287
GAF: 122844596
CVG: 107084171
NFU: 107386732
AOCE: 111573091
MCEP: 125021858
CSEM: 103395485(il2rg)
POV: 109635689
SSEN: 122779628
SDU: 111217233(il2rg)
SLAL: 111672069
XGL: 120802360
HCQ: 109512452
BPEC: 110164068
MALB: 109960011
BSPL: 114869401
OMY: 100136033 101268908(il2rc2)
SALP: 111964368
LCM: 102356230(IL2RG)
 » show all
Takeshita T, Asao H, Ohtani K, Ishii N, Kumaki S, Tanaka N, Munakata H, Nakamura M, Sugamura K
Cloning of the gamma chain of the human IL-2 receptor.
Science 257:379-82 (1992)
Minami Y, Kono T, Miyazaki T, Taniguchi T
The IL-2 receptor complex: its structure, function, and target genes.
Annu Rev Immunol 11:245-68 (1993)
Zhang Q, Wang HY, Liu X, Bhutani G, Kantekure K, Wasik M
IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.
Proc Natl Acad Sci U S A 108:11977-82 (2011)

DBGET integrated database retrieval system