KEGG   ORTHOLOGY: K05126
Entry
K05126                      KO                                     

Name
RET
Definition
proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
Pathway
ko05200  Pathways in cancer
ko05216  Thyroid cancer
ko05230  Central carbon metabolism in cancer
Disease
H00032  Thyroid cancer
H00247  Multiple endocrine neoplasia syndrome
H00910  Hirschsprung disease
H00916  Congenital central hypoventilation syndrome
H01510  Malignant paraganglioma
H01592  Medullary thyroid cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05126  RET; proto-oncogene tyrosine-protein kinase Ret
   05230 Central carbon metabolism in cancer
    K05126  RET; proto-oncogene tyrosine-protein kinase Ret
  09162 Cancer: specific types
   05216 Thyroid cancer
    K05126  RET; proto-oncogene tyrosine-protein kinase Ret
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05126  RET; proto-oncogene tyrosine-protein kinase Ret
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05126  RET; proto-oncogene tyrosine-protein kinase Ret
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  RET family
   K05126  RET; proto-oncogene tyrosine-protein kinase Ret
Genes
HSA: 5979(RET)
PTR: 100612888(RET)
PPS: 100994039(RET)
GGO: 101141559(RET)
PON: 100442682(RET)
NLE: 100602103(RET)
MCC: 703466(RET)
MCF: 102135879(RET)
CSAB: 103215755(RET)
RRO: 104653928(RET)
RBB: 108513309(RET)
CJC: 100403596(RET)
SBQ: 101053966(RET)
MMU: 19713(Ret)
MCAL: 110295751(Ret)
MPAH: 110315801(Ret)
RNO: 24716(Ret)
CGE: 100772741(Ret)
NGI: 103733801(Ret)
HGL: 101717565(Ret)
CCAN: 109676742(Ret)
OCU: 100340710(RET)
TUP: 102497228(RET)
CFA: 403494(RET)
VVP: 112913604(RET)
AML: 100467317(RET)
UMR: 103668071
UAH: 113243095(RET)
ORO: 101372117(RET)
ELK: 111145007
FCA: 101101086(RET)
PTG: 102951366(RET)
PPAD: 109264617(RET)
AJU: 106972131(RET)
BTA: 515924(RET)
BOM: 102284923(RET)
BIU: 109553788(RET)
BBUB: 102404389(RET)
CHX: 102172412(RET)
OAS: 101119787(RET)
SSC: 100155053(RET)
CFR: 102514431(RET)
CDK: 105092504(RET)
BACU: 103006627(RET)
LVE: 103069161(RET)
OOR: 101288280(RET)
DLE: 111163990(RET)
PCAD: 102984604(RET)
ECB: 100146791(RET)
EPZ: 103550619(RET)
EAI: 106831339(RET)
MYB: 102238841(RET)
MYD: 102766212(RET)
MNA: 107532547(RET)
HAI: 109395552(RET)
DRO: 112305517(RET)
PALE: 102878133(RET)
RAY: 107517623(RET)
MJV: 108392617(RET)
LAV: 100672176(RET)
TMU: 101357522
MDO: 100016023(RET)
SHR: 100927200(RET)
PCW: 110221483(RET)
OAA: 100076319(RET)
GGA: 396107(RET)
MGP: 100550243(RET)
CJO: 107315612(RET)
NMEL: 110399502(RET)
APLA: 101803164(RET)
ACYG: 106032512(RET)
TGU: 100219340(RET)
LSR: 110468614(RET)
SCAN: 103814210(RET)
GFR: 102042884(RET)
FAB: 101812108(RET)
PHI: 102107711(RET)
PMAJ: 107207043(RET)
CCAE: 111931023(RET)
CCW: 104690242(RET)
ETL: 114062798(RET)
FPG: 101922216(RET)
FCH: 102048122(RET)
CLV: 102083695(RET)
EGZ: 104128999(RET)
NNI: 104015433(RET)
ACUN: 113483380(RET)
PADL: 103924216(RET)
AAM: 106498889(RET)
ASN: 102371199(RET)
AMJ: 102573157(RET)
PSS: 102459127(RET)
CMY: 102940624(RET)
CPIC: 101938031(RET)
ACS: 100563549(ret)
PVT: 110083673(RET)
PBI: 103058664(RET)
PMUR: 107293255(RET)
TSR: 106555050(RET)
PMUA: 114597095(RET)
GJA: 107122192(RET)
XLA: 108696288(ret.L) 373625(ret.S)
XTR: 100495902(ret)
NPR: 108786609(RET)
DRE: 30512(ret)
SGH: 107559333(ret) 107601801
IPU: 108262651(ret)
PHYP: 113537802(ret)
AMEX: 103028663(ret)
EEE: 113585232(ret)
TRU: 101070188(ret)
LCO: 104921882(ret)
NCC: 104952732(ret)
ONL: 100702608(ret)
OLA: 101156037(ret)
XMA: 102237488(ret)
XCO: 114137568(ret)
PRET: 103477116(ret)
CVG: 107088598(ret)
NFU: 107375369(ret)
KMR: 108240623(ret)
ALIM: 106525613(ret)
AOCE: 111573084(ret)
CSEM: 103387460(ret)
POV: 109636804(ret)
LCF: 108886252(ret)
SDU: 111220596(ret)
SLAL: 111669539(ret)
HCQ: 109523240(ret)
BPEC: 110162334(ret)
MALB: 109958407(ret)
ELS: 105028647(ret)
SFM: 108932773(ret)
PKI: 111848989(ret)
LCM: 102358285(RET)
CMK: 103182663(ret)
RTP: 109921507(ret)
DME: Dmel_CG14396(Ret)
DER: 6548796
DSE: 6618258
DSI: Dsimw501_GD21645(Dsim_GD21645)
DSR: 110187405
DPE: 6593673
DMN: 108161877
DWI: 6646561
DAZ: 108610714
DNV: 115562752
DHE: 111599187
DVI: 6628028
MDE: 101890374
LCQ: 111678362
AME: 412667
BIM: 100741376
BTER: 100652108
CCAL: 108629271
OBB: 114877604
SOC: 105196030
MPHA: 105840080
AEC: 105147214
ACEP: 105619637
PBAR: 105426764
VEM: 105559591
HST: 105181042
DQU: 106748675
CFO: 105250051
LHU: 105668422
PGC: 109856241
OBO: 105284132
PCF: 106791228
NVI: 100120941
CSOL: 105364381
MDL: 103571463
TCA: 657748(ret)
DPA: 109545599
ATD: 109596516
NVL: 108566823
API: 100164983
DNX: 107168806
AGS: 114123818
RMD: 113547799
CLEC: 106662253
ZNE: 110831101
FCD: 110856673
EPA: 110251418
 » show all
Reference
  Authors
Santoro M, Melillo RM, Carlomagno F, Vecchio G, Fusco A
  Title
Minireview: RET: normal and abnormal functions.
  Journal
Endocrinology 145:5448-51 (2004)
DOI:10.1210/en.2004-0922
Reference
  Authors
Jhiang SM
  Title
The RET proto-oncogene in human cancers.
  Journal
Oncogene 19:5590-7 (2000)
DOI:10.1038/sj.onc.1203857
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