KEGG   ORTHOLOGY: K05208
Entry
K05208                      KO                                     

Name
GRIN1
Definition
glutamate receptor ionotropic, NMDA 1
Pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05033  Nicotine addiction
ko05034  Alcoholism
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04015 Rap1 signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04020 Calcium signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04024 cAMP signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04720 Long-term potentiation
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05014 Amyotrophic lateral sclerosis
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05016 Huntington disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05017 Spinocerebellar ataxia
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05020 Prion disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05022 Pathways of neurodegeneration - multiple diseases
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  09165 Substance dependence
   05030 Cocaine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05031 Amphetamine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05033 Nicotine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05034 Alcoholism
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Ion channels [BR:ko04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Other DBs
GO: 0004972 0005234
TC: 1.A.10.1.6 1.A.10.1.12
Genes
HSA: 2902(GRIN1)
PTR: 465176(GRIN1)
PPS: 100987673(GRIN1)
GGO: 101146203(GRIN1)
PON: 100435177(GRIN1)
NLE: 100607572(GRIN1)
MCC: 574380(GRIN1)
MCF: 102115033(GRIN1)
CSAB: 103239575(GRIN1)
RRO: 104669771(GRIN1)
RBB: 108542864(GRIN1)
CJC: 100413857(GRIN1)
SBQ: 101054145(GRIN1)
MMU: 14810(Grin1)
MCAL: 110285719(Grin1)
MPAH: 110319261(Grin1)
RNO: 24408(Grin1)
MUN: 110556997(Grin1)
CGE: 100770880(Grin1)
NGI: 103732604(Grin1)
HGL: 101720185(Grin1)
CCAN: 109687368
TUP: 102469683(GRIN1)
CFA: 494007(GRIN1)
VVP: 112911422(GRIN1)
AML: 100465687(GRIN1)
UMR: 103675310(GRIN1)
ORO: 101368224(GRIN1)
FCA: 101082021(GRIN1)
PTG: 102949242(GRIN1)
PPAD: 109260229(GRIN1)
AJU: 106989187(GRIN1)
BTA: 100336579(GRIN1)
BOM: 102276953(GRIN1)
BBUB: 102403040(GRIN1)
CHX: 102181789(GRIN1)
OAS: 443281(GRIN1)
SSC: 397440(GRIN1)
CFR: 102506181(GRIN1)
CDK: 105106183(GRIN1)
BACU: 103001022(GRIN1)
LVE: 103085162(GRIN1)
OOR: 101278622(GRIN1)
DLE: 111176991(GRIN1)
PCAD: 102987558(GRIN1)
ECB: 100059861(GRIN1)
EPZ: 103563588(GRIN1)
EAI: 106822778(GRIN1)
MYB: 102240692(GRIN1)
MYD: 102751770(GRIN1)
MNA: 107536149(GRIN1)
HAI: 109382502(GRIN1)
DRO: 112306277(GRIN1)
PALE: 102894415(GRIN1)
RAY: 107503090(GRIN1)
MJV: 108388298(GRIN1)
LAV: 100663779(GRIN1)
TMU: 101349517
MDO: 100023485(GRIN1)
SHR: 100922600(GRIN1)
PCW: 110205260(GRIN1)
OAA: 100082705(GRIN1)
GGA: 404296(GRIN1)
MGP: 100548054(GRIN1)
CJO: 107321672(GRIN1)
NMEL: 110406928(GRIN1)
APLA: 101789524(GRIN1)
ACYG: 106037054(GRIN1)
TGU: 751779(GRIN1)
LSR: 110472204(GRIN1)
SCAN: 103819186(GRIN1)
GFR: 102040955(GRIN1)
FAB: 101818610(GRIN1)
PHI: 102108893(GRIN1)
PMAJ: 107212141(GRIN1)
CCAE: 111936905(GRIN1)
CCW: 104688213(GRIN1)
ETL: 114064163(GRIN1)
FPG: 101913185(GRIN1)
FCH: 102047364(GRIN1)
CLV: 102098434(GRIN1)
EGZ: 104123999(GRIN1)
NNI: 104022714(GRIN1)
ACUN: 113486654(GRIN1)
PADL: 103918966(GRIN1)
AAM: 106487018(GRIN1)
ASN: 102370900(GRIN1)
AMJ: 102571725(GRIN1)
PSS: 102453445(GRIN1)
CMY: 102936758
CPIC: 101935314(GRIN1)
ACS: 100553024(grin1)
PVT: 110087451(GRIN1)
PBI: 103066289(GRIN1)
PMUR: 107302534(GRIN1)
TSR: 106541972(GRIN1)
PMUA: 114606269 114606384(GRIN1)
GJA: 107115159(GRIN1)
XLA: 108699855 397953(grin1.S)
XTR: 780048(grin1)
NPR: 108795933(GRIN1)
DRE: 100005675(grin1b) 767745(grin1a)
IPU: 108255876(grin1) 108278500
PHYP: 113535563 113536981(grin1)
LCO: 104936329(grin1)
NCC: 104966793(grin1)
BPEC: 110159188 110164000(grin1)
LCM: 102356038(GRIN1)
CMK: 103183009(grin1)
RTP: 109916194(grin1)
BFO: 118406774
CIN: 100186847
APLC: 110991116
SKO: 100370156
DME: Dmel_CG2902(Nmdar1)
DER: 6552207
DSE: 6613956
DSI: Dsimw501_GD19612(Dsim_GD19612)
DAN: 6500487
DSR: 110177232
DPE: 6591341
DMN: 108155503
DWI: 6641663
DNV: 108656036
DHE: 111603663
DVI: 6630672
MDE: 101898320
LCQ: 111680158
AALB: 109401442
AME: 406079(Nmdar1)
BIM: 100749947
BTER: 100644436
CCAL: 108627351
OBB: 114880618
SOC: 105201093
MPHA: 105832305
AEC: 105145837
ACEP: 105618959
PBAR: 105434122
VEM: 105570583
HST: 105182141
DQU: 106743549
CFO: 105258574
LHU: 105668471
PGC: 109857911
OBO: 105277859
PCF: 106791773
NVI: 100116847
CSOL: 105361136
MDL: 103580278
TCA: 658152
DPA: 109537645
ATD: 109594466
NVL: 108562030
BMOR: 101743090
BMAN: 114239380
PMAC: 106715411
PRAP: 110995370
HAW: 110377196
TNL: 113499389
PXY: 105389024
API: 100160524
DNX: 107162112
AGS: 114132519
RMD: 113549434
BTAB: 109031908
CLEC: 106661247
ZNE: 110837591
FCD: 110851005
PVM: 113812935
CSCU: 111639667
PTEP: 107441166
CEL: CELE_F07F6.6(nmr-1)
CBR: CBG02401(Cbr-nmr-1)
PCAN: 112565911
CRG: 105333721
MYI: 110451795
OBI: 106884058
LAK: 106178045
SHX: MS3_00804
ADF: 107354805
HMG: 100197210
SMIN: v1.2.020958.t1(symbB.v1.2.020958.t1)
 » show all
Reference
PMID:7685113
  Authors
Planells-Cases R, Sun W, Ferrer-Montiel AV, Montal M
  Title
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
  Journal
Proc Natl Acad Sci U S A 90:5057-61 (1993)
DOI:10.1073/pnas.90.11.5057
  Sequence
[hsa:2902]
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