KEGG   ORTHOLOGY: K05406
Entry
K05406                      KO                                     

Name
IL12A
Definition
interleukin 12A
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04620  Toll-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04940  Type I diabetes mellitus
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05143  African trypanosomiasis
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05162  Measles
ko05164  Influenza A
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
ko05330  Allograft rejection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05406  IL12A; interleukin 12A
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05406  IL12A; interleukin 12A
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05406  IL12A; interleukin 12A
   04622 RIG-I-like receptor signaling pathway
    K05406  IL12A; interleukin 12A
   04625 C-type lectin receptor signaling pathway
    K05406  IL12A; interleukin 12A
   04658 Th1 and Th2 cell differentiation
    K05406  IL12A; interleukin 12A
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05406  IL12A; interleukin 12A
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05406  IL12A; interleukin 12A
   05330 Allograft rejection
    K05406  IL12A; interleukin 12A
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K05406  IL12A; interleukin 12A
  09171 Infectious disease: bacterial
   05133 Pertussis
    K05406  IL12A; interleukin 12A
   05134 Legionellosis
    K05406  IL12A; interleukin 12A
   05152 Tuberculosis
    K05406  IL12A; interleukin 12A
  09172 Infectious disease: viral
   05162 Measles
    K05406  IL12A; interleukin 12A
   05164 Influenza A
    K05406  IL12A; interleukin 12A
   05168 Herpes simplex virus 1 infection
    K05406  IL12A; interleukin 12A
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K05406  IL12A; interleukin 12A
   05144 Malaria
    K05406  IL12A; interleukin 12A
   05145 Toxoplasmosis
    K05406  IL12A; interleukin 12A
   05140 Leishmaniasis
    K05406  IL12A; interleukin 12A
   05142 Chagas disease
    K05406  IL12A; interleukin 12A
   05143 African trypanosomiasis
    K05406  IL12A; interleukin 12A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05406  IL12A; interleukin 12A
   00536 Glycosaminoglycan binding proteins
    K05406  IL12A; interleukin 12A
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05406  IL12A; interleukin 12A
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Cytokines
   K05406  IL12A; interleukin 12A
Other DBs
GO: 0005143
Genes
HSA: 3592(IL12A)
PTR: 460816(IL12A)
PPS: 100979574(IL12A)
GGO: 101150677(IL12A)
PON: 100444807(IL12A)
NLE: 100603245(IL12A)
MCC: 703205(IL12A)
MCF: 102115316(IL12A)
CSAB: 103241402(IL12A)
RRO: 104665012(IL12A)
RBB: 108514790(IL12A)
CJC: 100406669(IL12A)
SBQ: 101044358(IL12A)
MMU: 16159(Il12a)
MCAL: 110291699(Il12a)
MPAH: 110320680(Il12a)
RNO: 84405(Il12a)
MUN: 110557307(Il12a)
CGE: 100760602(Il12a)
NGI: 103745345(Il12a)
HGL: 101701392(Il12a)
CCAN: 109692199(Il12a)
OCU: 100349007(IL12A)
TUP: 102493627(IL12A)
CFA: 403977(IL12A)
VVP: 112933314(IL12A)
AML: 100470471(IL12A)
UMR: 103681335(IL12A)
UAH: 113254130(IL12A)
ORO: 101367178(IL12A)
ELK: 111150468
FCA: 493741(IL12A)
PTG: 102971802(IL12A)
PPAD: 109262066(IL12A)
AJU: 106969467(IL12A)
BTA: 281856(IL12A)
BOM: 102276398(IL12A)
BIU: 109564477(IL12A)
BBUB: 102406980(IL12A)
CHX: 100861293(IL12A)
OAS: 443064(IL12A)
SSC: 397053(IL12A)
CFR: 102507202(IL12A)
CDK: 105094260(IL12A)
BACU: 103003516(IL12A)
LVE: 103079299(IL12A)
OOR: 101279088(IL12A)
DLE: 111174517(IL12A)
PCAD: 102982335(IL12A)
ECB: 100034215(IL12A)
EPZ: 103562911(IL12A)
EAI: 106824114(IL12A)
MYB: 102251395(IL12A)
MYD: 102753538(IL12A)
MNA: 107539273(IL12A)
HAI: 109373148(IL12A)
DRO: 112304655(IL12A)
PALE: 102887571(IL12A)
RAY: 107512954(IL12A)
MJV: 108409113(IL12A)
LAV: 100665137(IL12A)
TMU: 101353752
MDO: 100018516(IL12A)
SHR: 100914201(IL12A)
PCW: 110210080(IL12A)
OAA: 100086041(IL12A)
GGA: 407090(IL12A)
MGP: 100542954(IL12A)
CJO: 107318422(IL12A)
NMEL: 110397416(IL12A)
APLA: 113844483(IL12A)
ACYG: 106043510(IL12A)
LSR: 110476606(IL12A)
FAB: 101809609(IL12A)
CCW: 104688158(IL12A)
ETL: 114062930(IL12A)
FPG: 101915475(IL12A)
FCH: 102047690(IL12A)
CLV: 102091031(IL12A)
EGZ: 104122263(IL12A)
NNI: 104011599(IL12A)
ACUN: 113483415(IL12A)
PADL: 103925294(IL12A)
AAM: 106495099(IL12A)
ASN: 102368752(IL12A)
AMJ: 102576541(IL12A)
PSS: 102457029(IL12A)
CMY: 102945506(IL12A)
CPIC: 101945519(IL12A)
XTR: 101734580
DRE: 100004358(zmp:0000001127) 445410(il12a)
IPU: 108267859
PHYP: 113540201
EEE: 113588304
TRU: 115247888 446069(il12a)
LCO: 104936631
XMA: 111612051
XCO: 114161440
PRET: 103474728
CVG: 107081893
NFU: 107380562
AOCE: 111572772
CSEM: 103378499
POV: 109638746
LCF: 108883223
HCQ: 109518416
BPEC: 110159295
MALB: 109957731
OTW: 112244633
SALP: 111979755
ELS: 109616205
PKI: 111841504(il12a) 111847694
CMK: 103176349(il12a)
 » show all
Reference
PMID:1673147
  Authors
Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, Dzialo R, Fitz L, Ferenz C, Hewick RM, et al.
  Title
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.
  Journal
J Immunol 146:3074-81 (1991)
  Sequence
[hsa:3592]
Reference
  Authors
Klinke DJ 2nd
  Title
A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12.
  Journal
Mol Cancer 9:242 (2010)
DOI:10.1186/1476-4598-9-242
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