KEGG ORTHOLOGY: K05453

ORTHOLOGY: K05453

Entry

K05453                      KO

Symbol

CSF1, MCSF

Name

macrophage colony-stimulating factor 1

Pathway

map04010

MAPK signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04060

Cytokine-cytokine receptor interaction

map04061

Viral protein interaction with cytokine and cytokine receptor

map04151

PI3K-Akt signaling pathway

map04380

Osteoclast differentiation

map04640

Hematopoietic cell lineage

map04668

TNF signaling pathway

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05323

Rheumatoid arthritis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   04014 Ras signaling pathway
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   04015 Rap1 signaling pathway
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   04668 TNF signaling pathway
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   04151 PI3K-Akt signaling pathway
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
   05022 Pathways of neurodegeneration - multiple diseases
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  CSF and other factors
   K05453  CSF1, MCSF; macrophage colony-stimulating factor 1

Genes

HSA:	1435(CSF1)

PTR:	457127(CSF1)

PPS:	100994576(CSF1)

GGO:	101131872(CSF1)

PON:	100452144(CSF1)

NLE:	100590081(CSF1)

HMH:	116469641(CSF1)

MCC:	702532(CSF1)

MCF:	102141631(CSF1)

MTHB:

126929640

MNI:	105479257(CSF1)

CSAB:

103224269(CSF1)

CATY:

105594352(CSF1)

PANU:

101016725(CSF1)

TGE:	112605466(CSF1)

MLEU:

105531934(CSF1)

RRO:	104680325(CSF1)

RBB:	108528053(CSF1)

TFN:	117074284(CSF1)

PTEH:

111556006(CSF1)

CANG:

105516054(CSF1)

CJC:	100386071(CSF1)

SBQ:	101036115(CSF1)

CIMI:

108283129(CSF1)

CSYR:

103269079(CSF1)

MMUR:

105864049(CSF1)

LCAT:

123635010(CSF1)

PCOQ:

105825541(CSF1)

OGA:	100942777(CSF1)

MMU:	12977(Csf1)

MCAL:

110291496(Csf1)

MPAH:

110320052(Csf1)

RNO:	78965(Csf1)

MCOC:

116093601(Csf1)

ANU:	117706885(Csf1)

MUN:	110545505(Csf1)

CGE:	100767142(Csf1)

MAUA:

101826376(Csf1)

PROB:

127216878(Csf1)

PLEU:

114700000(Csf1)

MORG:

121438069 121452722

MFOT:

126491876

AAMP:

119801389(Csf1)

NGI:	103747824(Csf1)

HGL:	101709756(Csf1)

CPOC:

100732898(Csf1)

CCAN:

109694805(Csf1)

DORD:

105997488(Csf1)

DSP:	122109178(Csf1)

PLOP:

125355432(Csf1)

NCAR:

124969224

MMMA:

107158610(Csf1)

OCU:

100338577

OPI:	101530838(CSF1)

TUP:	102492960(CSF1)

GVR:	103585638(CSF1)

CFA:	611795(CSF1)

CLUD:

112640696(CSF1)

VVP:	112918277(CSF1)

VLG:	121487528(CSF1)

NPO:	129519645(CSF1)

AML:	100467411(CSF1)

UMR:	103675205(CSF1)

UAH:	113244914(CSF1)

UAR:	123795095(CSF1)

ELK:

111143313

LLV:

125098134

MPUF:

101686911(CSF1)

MNP:	132001267(CSF1)

MLK:	131809395(CSF1)

NVS:	122900302(CSF1)

ORO:	101365427(CSF1)

EJU:	114207930(CSF1)

ZCA:	113935588(CSF1)

MLX:	118019025(CSF1)

NSU:	110580319(CSF1)

LWW:	102741318(CSF1)

FCA:	101091467(CSF1)

PYU:	121027641(CSF1)

PCOO:

112871949(CSF1)

PBG:	122480903(CSF1)

PVIV:

125172928(CSF1)

LRUF:

124515520

PTG:	102972710(CSF1)

PPAD:

109272007(CSF1)

PUC:

125912284

AJU:

106977865

HHV:	120244521(CSF1)

BTA:	281094(CSF1)

BOM:	102269710(CSF1)

BIU:	109555962(CSF1)

BBUB:

102395229(CSF1)

BBIS:

104981661(CSF1)

CHX:	102185051(CSF1)

OAS:	101104200(CSF1)

BTAX:

128044745(CSF1)

ODA:	120856721(CSF1)

CCAD:

122436569(CSF1)

MBEZ:

129541681(CSF1)

SSC:	100513084(CSF1)

CFR:	102518652(CSF1)

CBAI:

105063662(CSF1)

CDK:	105085658(CSF1)

VPC:	102528464(CSF1)

BACU:

103005966(CSF1)

BMUS:

118897217(CSF1)

LVE:	103077876(CSF1)

OOR:	101278934(CSF1)

DLE:	111180064(CSF1)

PCAD:

102974293(CSF1)

PSIU:

116756768(CSF1)

NASI:

112397834(CSF1)

ECB:	100146493(CSF1)

EPZ:	103557529(CSF1)

EAI:	106827389(CSF1)

MYB:	102263365(CSF1)

MYD:	102766818(CSF1)

MMYO:

118672850(CSF1)

MLF:	102429105(CSF1)

PKL:	118727454(CSF1)

EFUS:

103291338(CSF1)

MNA:	107545236(CSF1)

DRO:	112313968(CSF1)

SHON:

118981911(CSF1)

AJM:	119054540(CSF1)

PDIC:

114489238(CSF1)

PHAS:

123804682(CSF1)

MMF:	118637506(CSF1)

PPAM:

129063699(CSF1)

HAI:	109371584(CSF1)

RFQ:	117014994(CSF1)

PALE:

102894339(CSF1)

PGIG:

120584998(CSF1)

PVP:	105297143(CSF1)

RAY:	107516132(CSF1)

MJV:	108400987(CSF1)

TOD:	119235789(CSF1)

SARA:

101547814(CSF1)

LAV:	100670704(CSF1)

TMU:

101357438

ETF:	101657479(CSF1)

DNM:	101433349(CSF1)

MDO:	100033077(CSF1)

GAS:	123246710(CSF1)

SHR:	100930278(CSF1)

AFZ:

127559368

PCW:	110218309(CSF1)

OAA:	100073393(CSF1)

GGA:	100499189(CSF1)

PCOC:

116237023(CSF1)

MGP:	100549089(CSF1)

CJO:	107324667(CSF1)

TPAI:

128088187(CSF1)

LMUT:

125684239(CSF1)

NMEL:

110388070(CSF1)

APLA:

101804317(CSF1)

ACYG:

106048436(CSF1)

CATA:

118260397(CSF1)

AFUL:

116498783(CSF1)

TGU:	100499187(CSF1)

LSR:	110469193(CSF1)

SCAN:

103822422(CSF1)

PMOA:

120502260(CSF1)

OTC:	121345642(CSF1)

PRUF:

121365460(CSF1)

GFR:	102039316(CSF1)

FAB:	101815683(CSF1)

OMA:	130263757(CSF1)

PHI:	102099590(CSF1)

PMAJ:

107214717(CSF1)

CCAE:

111939755(CSF1)

CCW:	104692438(CSF1)

CBRC:

103619487(CSF1)

ETL:	114071378(CSF1)

ZAB:	102063389(CSF1)

ACHL:

103811172(CSF1)

SVG:	106851092(CSF1)

MMEA:

130578883(CSF1)

HRT:	120762945(CSF1)

FPG:	101918873(CSF1)

FCH:	102056981(CSF1)

CLV:	102096751(CSF1)

EGZ:	104127764(CSF1)

NNI:	104018429(CSF1)

PCRI:

104037670(CSF1)

EHS:	104510532(CSF1)

PCAO:

104041091(CSF1)

ACUN:

113489043(CSF1)

TALA:

104360227(CSF1)

PADL:

103925944(CSF1)

AFOR:

103908277(CSF1)

ACHC:

115335407(CSF1)

HALD:

104326015(CSF1)

HLE:	104842446(CSF1)

AGEN:

126052233

GCL:

127026222

CCRI:

104165318(CSF1)

CSTI:

104560172(CSF1)

CMAC:

104477927(CSF1)

MUI:	104536061(CSF1)

BREG:

104632167(CSF1)

FGA:	104077581(CSF1)

GSTE:

104256136(CSF1)

LDI:	104352046(CSF1)

OHA:	104328137(CSF1)

NNT:	104404923(CSF1)

SHAB:

115602271(CSF1)

DPUB:

104301078(CSF1)

ACAR:

104523441(CSF1)

CPEA:

104393427(CSF1)

AVIT:

104278085(CSF1)

CVF:	104287802(CSF1)

RTD:	128900397(CSF1)

CUCA:

104059003(CSF1)

TEO:	104374744(CSF1)

BRHI:

104492271(CSF1)

AROW:

112961471(CSF1)

NPD:	112944601(CSF1)

TGT:	104566840(CSF1)

DNE:	112990372(CSF1)

ASN:	102376334(CSF1)

AMJ:	102560814(CSF1)

CPOO:

109317538(CSF1)

GGN:	109295181(CSF1)

PSS:	102451139(CSF1)

CMY:	102929703(CSF1)

CCAY:

125625171(CSF1)

DCC:	119846278(CSF1)

CPIC:

101951664(CSF1)

TST:	117875945(CSF1)

CABI:

116833832(CSF1)

MRV:	120404953(CSF1)

ACS:	103278674(csf1)

ASAO:

132773787(CSF1)

PVT:	110087976(CSF1)

SUND:

121929264(CSF1)

PBI:	103049576(CSF1)

PMUR:

107286268(CSF1)

CTIG:

120298943(CSF1)

TSR:	106551233(CSF1)

PGUT:

117664055(CSF1)

APRI:

131194296(CSF1)

PTEX:

113440646(CSF1)

NSS:	113418820 113418946

VKO:	123029887(CSF1)

PMUA:

114599167(CSF1)

PRAF:

128415943(CSF1)

ZVI:	118088941(CSF1)

GJA:	107106414(CSF1)

STOW:

125433965(CSF1)

EMC:	129331153(CSF1)

XLA:	101243553(csf1.S)

RTEM:

120927158

MUO:	115481878(CSF1)

GSH:	117347418(CSF1)

DRE:	100004617(csf1a)

SRX:	107727738 107739300

SANH:

107656002

SGH:

107556909

CCAR:

109070122 109092295 109109927

CAUA:

113111209

CGIB:

127968450

PTET:

122354110(csf1a)

LROH:

127173125(csf1a)

OMC:	131549842(csf1a)

PPRM:

120495491(csf1a)

RKG:	130103579(csf1a)

MAMB:

125256822(csf1a)

CIDE:

127522054

MASI:

127427984

TROS:

130571733(csf1a)

TDW:	130410434(csf1a)

MANU:

129427841(csf1a)

IPU:	108280990(csf1a)

IFU:	128625342(csf1a)

PHYP:

113539503

SMEO:

124402506(csf1a)

TFD:	113641579(csf1a)

TVC:	132838317(csf1a)

AMEX:

103045744

CMAO:

118799836(csf1a)

EEE:

113589084

SASA:

106565101 106583500(csf1)

STRU:

115150302(csf1) 115208130

OTW:	112244887 112255312(csf1a)

OMY:	100136089(csf1) 110528367(csf1a)

OGO:	124002365 124019062

ONE:	115142586(csf1) 115142936

OKI:	109890267(csf1) 109893129

OKE:	118388828 118400500(csf1a)

SALP:

111963545 111970343(csf1)

SNH:

120026095

CCLU:

121575403

ELS:

105016804

SFM:	108938164(csf1)

PKI:	111841531(csf1)

AANG:

118208353 118211664(csf1a)

LOC:

PSPA:

ARUT:

Reference

PMID:3493529

Authors

Wong GG, Temple PA, Leary AC, Witek-Giannotti JS, Yang YC, Ciarletta AB, Chung M, Murtha P, Kriz R, Kaufman RJ, et al.

Title

Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.

Journal

Science 235:1504-8 (1987)
DOI:10.1126/science.3493529

Sequence

[hsa:1435]

LinkDB

DBGET integrated database retrieval system