KEGG   ORTHOLOGY: K05463
Entry
K05463                      KO                                     

Name
EFNB
Definition
ephrin-B
Pathway
ko04360  Axon guidance
Disease
H00458  Syndromic craniosynostoses
H01992  Craniofrontonasal syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K05463  EFNB; ephrin-B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K05463  EFNB; ephrin-B
   04052 Cytokines and growth factors
    K05463  EFNB; ephrin-B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K05463  EFNB; ephrin-B
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K05463  EFNB; ephrin-B
Genes
HSA: 1947(EFNB1) 1948(EFNB2) 1949(EFNB3)
PTR: 473651(EFNB1) 735430(EFNB2) 750632(EFNB3)
PPS: 100971909(EFNB1) 100972361(EFNB2) 100973594(EFNB3)
GGO: 101142718(EFNB2) 101149299(EFNB1)
PON: 100437201(EFNB2) 100443625(EFNB1) 100458568(EFNB3)
NLE: 100581094(EFNB3) 100583294(EFNB2) 100606933(EFNB1)
MCC: 694149(EFNB1) 711288(EFNB2) 716257(EFNB3)
MCF: 102117432(EFNB2) 102123263(EFNB1) 102137415(EFNB3)
CSAB: 103214766(EFNB2) 103232118(EFNB1) 103242324(EFNB3)
RRO: 104654005(EFNB2) 104656743(EFNB1) 104661664(EFNB3)
RBB: 108514364(EFNB3) 108519174(EFNB1) 108522644(EFNB2)
CJC: 100397067(EFNB2) 100405967(EFNB1) 100414985(EFNB3)
SBQ: 101033574(EFNB1) 101040248(EFNB2) 101044726(EFNB3)
MMU: 13641(Efnb1) 13642(Efnb2) 13643(Efnb3)
MCAL: 110287268(Efnb1) 110299811(Efnb2) 110305906(Efnb3)
MPAH: 110313840(Efnb1) 110332152(Efnb3) 110336438(Efnb2)
RNO: 25186(Efnb1) 306636(Efnb2) 360546(Efnb3)
MUN: 110553065(Efnb2) 110555155(Efnb3) 110559164(Efnb1)
CGE: 100753573(Efnb2) 100755216(Efnb1) 100756800(Efnb3) 103158763 103162695 113831860 113837977 113838057 113838063 113838916 113838971 113839047 113839076
NGI: 103724481(Efnb2) 103743149(Efnb1) 103752114(Efnb3)
HGL: 101702951(Efnb3) 101705409(Efnb1) 101723880(Efnb2)
CCAN: 109674218(Efnb3) 109681390(Efnb2) 109684859(Efnb1)
OCU: 100338775(EFNB1) 100352864(EFNB3) 100357479(EFNB2)
TUP: 102474439(EFNB1) 102492352(EFNB2) 102502532(EFNB3)
CFA: 607410(EFNB1) 607903(EFNB3) 611745(EFNB2)
VVP: 112907604(EFNB1) 112924855(EFNB3) 112927477(EFNB2)
AML: 100469018 100474281(EFNB1) 100476801(EFNB2)
UMR: 103657551(EFNB2) 103660478(EFNB3) 103682628(EFNB1)
UAH: 113245651(EFNB1) 113251527(EFNB2) 113271153(EFNB3)
ORO: 101376345(EFNB2) 101381814(EFNB1) 101386773(EFNB3)
ELK: 111147124 111161013 111161214
FCA: 100135768(EFNB3) 100135769(EFNB2) 101082804(EFNB1)
PTG: 102961986(EFNB3) 102967935(EFNB2) 102968443(EFNB1)
PPAD: 109245922(EFNB3) 109254584(EFNB1) 109264086(EFNB2)
AJU: 106972438(EFNB3) 106976973(EFNB2) 106981655(EFNB1)
BTA: 100139818(EFNB2) 534413(EFNB1) 617714(EFNB3)
BOM: 102264592(EFNB2) 102272948(EFNB3) 102273327(EFNB1)
BIU: 109555355(EFNB1) 109566948(EFNB2) 109574502(EFNB3)
BBUB: 102400321(EFNB1) 102402384(EFNB3) 102406429(EFNB2)
CHX: 102168298(EFNB3) 102169974(EFNB2) 102183496(EFNB1)
OAS: 101103994(EFNB3) 101115469(EFNB2) 101120475(EFNB1)
SSC: 100135672(EFNB3) 100135673(EFNB2) 100624619(EFNB1)
CFR: 102503797(EFNB3) 102505246(EFNB1) 102506211(EFNB2)
CDK: 105087963(EFNB1) 105094089(EFNB2) 105103009(EFNB3)
BACU: 103002949(EFNB3) 103012042(EFNB1) 103013539(EFNB2)
LVE: 103072003(EFNB1) 103075484(EFNB2) 103090925(EFNB3)
OOR: 101272453 101282157(EFNB2) 101283099 101285159(EFNB3)
DLE: 111167808 111167809 111176400(EFNB2) 111185911(EFNB3)
PCAD: 102978749(EFNB2) 102978815(EFNB1) 102985094(EFNB3)
ECB: 100062080(EFNB3) 100064730(EFNB2) 100147489(EFNB1)
EPZ: 103543424(EFNB1) 103548605(EFNB2) 103557702(EFNB3)
EAI: 106823288(EFNB1) 106831539(EFNB2) 106844219(EFNB3)
MYB: 102245358(EFNB3) 102246218(EFNB2) 102258970(EFNB1)
MYD: 102758904(EFNB2) 102759755(EFNB3) 102774481(EFNB1)
MNA: 107530191(EFNB2) 107530211(EFNB1) 107544608(EFNB3)
HAI: 109385612(EFNB1) 109393968(EFNB2) 109394593(EFNB3)
DRO: 112300050(EFNB1) 112308843(EFNB3) 112321471(EFNB2)
PALE: 102883806(EFNB1) 102889394(EFNB2) 102890112(EFNB3)
RAY: 107497602(EFNB2) 107515688(EFNB3) 107517470(EFNB1)
MJV: 108394409(EFNB2) 108403864(EFNB1) 108404262(EFNB3)
LAV: 100669312(EFNB3) 100670243(EFNB1) 100677471(EFNB2)
TMU: 101351586 101352896 101361538
MDO: 100014241(EFNB3) 100014767(EFNB1) 100018256(EFNB2)
SHR: 100915166(EFNB3) 100927159(EFNB2) 100934560(EFNB1)
PCW: 110194272(EFNB3) 110196703(EFNB2) 110201084(EFNB1)
OAA: 100082180(EFNB2) 114808219(EFNB3) 114812803(EFNB1)
GGA: 395625(EFNB2) 395896(EFNB1)
MGP: 100538460(EFNB2) 100551372(EFNB1) 104912128
CJO: 107307960(EFNB2) 107312580(EFNB1)
NMEL: 110403139(EFNB1) 110407700(EFNB2)
APLA: 101795141(EFNB2)
ACYG: 106042948(EFNB1) 106044879(EFNB2)
TGU: 100219955(EFNB2) 100224613(EFNB1)
LSR: 110470526(EFNB2) 110474375(EFNB1) 110480309(EFNB3)
SCAN: 103812305(EFNB2) 103816426(EFNB1)
GFR: 102033514(EFNB1) 102037489(EFNB2)
FAB: 101820186(EFNB2) 101821793(EFNB1)
PHI: 102101467(EFNB1) 102110309(EFNB2) 106628764(EFNB3)
PMAJ: 107203938(EFNB1) 107209951(EFNB2)
CCAE: 111928737(EFNB1) 111944494(EFNB2)
CCW: 104686000(EFNB2) 104691281(EFNB1)
ETL: 114066965(EFNB2) 114068713(EFNB1)
FPG: 101916056(EFNB1) 101923538(EFNB2)
FCH: 102050060(EFNB2) 102057646(EFNB1)
CLV: 102084792(EFNB1) 102093625(EFNB2)
EGZ: 104126338(EFNB2) 104130403(EFNB1)
NNI: 104012836(EFNB1) 104017330(EFNB2)
ACUN: 113478481(EFNB2)
PADL: 103919183(EFNB1) 103924769(EFNB2)
AAM: 106484140(EFNB1) 106494020(EFNB2)
ASN: 102371119(EFNB1) 102377317(EFNB2) 102378505(EFNB3)
AMJ: 102559668(EFNB1) 102569085(EFNB2) 102571474(EFNB3)
PSS: 102449887(EFNB3) 102450930(EFNB2) 102461443(EFNB1) 106732345
CMY: 102931512(EFNB2) 102941901(EFNB3) 102947307(EFNB1)
CPIC: 101936654(EFNB3) 101948386 101953090(EFNB1) 101954123(EFNB2)
ACS: 100555761(efnb3) 100557682(efnb2) 100566589(efnb1)
PVT: 110074362(EFNB1) 110079351(EFNB2) 110087762(EFNB3)
PBI: 103050191 103052951(EFNB3) 103065838(EFNB1)
PMUR: 107283849 107291216 107297826
TSR: 106539447(EFNB2) 106541232 106548510(EFNB1)
PMUA: 114581553(EFNB3) 114589576(EFNB1) 114596498(EFNB2)
GJA: 107119378(EFNB2) 107119816(EFNB3) 107120582(EFNB1)
XLA: 100141484(efnb2.S) 108703540 378621(efnb3.L) 379645(efnb2.L) 394292(efnb1.L)
XTR: 100101723(efnb2) 100127666(efnb3) 100494328(efnb1)
NPR: 108785633(EFNB1) 108797865(EFNB2) 108802171(EFNB3)
DRE: 114377(efnb1) 114378(efnb3b) 114402(efnb2b) 30219(efnb2a) 564234(efnb3a)
SRX: 107705455 107707070(efnb3) 107709413 107711395 107720690 107725384 107738062 107742355 107746350 107757535
SANH: 107655917 107664264 107673116 107675360 107676033 107678015 107700912 107701778 107702056(efnb3) 107702517
SGH: 107548494 107555860 107563180 107565280 107586157 107590693 107595284(efnb3) 107596159 107597046
CCAR: 109058827 109061545 109065437 109072182 109083769 109105608 109111067 109111068
IPU: 108259076 108260051(efnb1) 108266449(efnb2) 108267882(efnb3) 108268434 108277042
PHYP: 113524152 113525499 113535160(efnb2) 113535822 113540471(efnb3) 113542750
AMEX: 103029287(efnb2) 103029645 103030347(efnb3) 103034681 103039530(efnb1) 103047315 111189583
EEE: 113574187 113579179 113580616 113581631(efnb2) 113585085 113591051
TRU: 101063508 101067624(efnb1) 101078775
TNG: GSTEN00005780G001 GSTEN00017917G001 GSTEN00029352G001 GSTEN00033075G001
LCO: 104922987 104925166(efnb1) 104925195 104940374(efnb2)
NCC: 104958963 104960227(efnb2) 104964883 104967673(efnb1)
MZE: 101464304 101466755(efnb1) 101469505(efnb2) 101478550
ONL: 100703532 100707941 100709263(efnb2) 100711032
OLA: 101160196 101172801 101173233(efnb1)
XMA: 102216434 102218296 102221882 102232342
XCO: 114138862(efnb1) 114142540 114148026 114157351
PRET: 103461794(efnb2) 103461951 103470907(efnb1) 103480564
CVG: 107082588(efnb2) 107084114(efnb3) 107089791(efnb1) 107090819
NFU: 107375977(efnb1) 107376934(efnb3) 107381149 107382754(efnb2)
KMR: 108237938(efnb1) 108242899(efnb3b) 108251174(efnb2a) 108251268
ALIM: 106510799 106513979(efnb2) 106525229 106533557
AOCE: 111568066 111571585(efnb3) 111573078 111588160
CSEM: 103378912 103390999(efnb3) 103391232(efnb1) 103392353(efnb2)
POV: 109624928 109637412(efnb2) 109639681 109644155
LCF: 108882771(efnb1) 108888043 108891848(efnb2) 108902163(efnb3)
SDU: 111226623(efnb1) 111228117(efnb2) 111231352 111238343
SLAL: 111646484(efnb1) 111647042 111663429(efnb2) 111668354
HCQ: 109515093 109519253 109519652 109524367(efnb1)
BPEC: 110158124(efnb1) 110158769 110163894 110173019
MALB: 109957586(efnb1) 109963157 109963781(efnb2) 109971927
SASA: 106563380 106567780 106577756 106581736(efnb2) 106586865 106591758 106603204 106603306 106608822 106612232
OTW: 112225262(efnb2) 112228731 112231372 112231400 112237344 112237824 112238439 112250250 112257667
SALP: 111951020 111959774(efnb2) 111964134 111980453 111980571 112075416
ELS: 105018709(efnb2) 105020117 105024434 105024600 105025027(efnb1) 105029889(efnb3)
SFM: 108929009(efnb2) 108929734 108931044 108932138 108934191 108938388
PKI: 111832768(efnb3) 111834136 111835533 111852895 111855933 111859870(efnb1)
LCM: 102345451 102350186(EFNB1) 102356232(EFNB2)
CMK: 103178623(efnb2) 103189369
RTP: 109911231 109933618
BFO: 118411210 118411608 118426872
CIN: 778593(ephrinb)
SPU: 115927222 763882
APLC: 110982372
SKO: 100329079 100369780
DME: Dmel_CG1862(Ephrin)
DER: 113563689 6555858
DSE: 6619467
DSI: Dsimw501_GD28434(Dsim_GD28434)
DYA: Dyak_GE14553
DSR: 110185409
DPO: Dpse_GA15017
DPE: 6602002
DMN: 108164455
DWI: 6651303
DGR: Dgri_GH24017
DMO: Dmoj_GI14050
DAZ: 108617898
DNV: 108657877
DHE: 111593713
LCQ: 111679765
AGA: AgaP_AGAP009426
AAG: 5564929
AALB: 109429599 115262101
CQU: CpipJ_CPIJ001112
AME: 727308
BIM: 100744521
BTER: 100644552
CCAL: 108624487
OBB: 114873542
SOC: 105196693
MPHA: 105836011
AEC: 105145374
ACEP: 105618124
PBAR: 105433881
VEM: 105566615
HST: 105190550
DQU: 106750794
CFO: 105255688
LHU: 105672660
PGC: 109860265
OBO: 105282577
PCF: 106787617
NVI: 100119767
CSOL: 105362489
MDL: 103576205
TCA: 655978 664511
DPA: 109536848
ATD: 109609657
NVL: 108560506 108563392
BMOR: 101736464
BMAN: 114241926
DPL: KGM_203864
PMAC: 106715236
PRAP: 110992669
HAW: 110369646
TNL: 113504213
PXY: 105393865
API: 100161694
DNX: 107169138
AGS: 114128162
RMD: 113559859
BTAB: 109038692
CLEC: 106670709
PHU: Phum_PHUM089410
ZNE: 110827211
FCD: 110858241
DPX: DAPPUDRAFT_308080
TUT: 107365671
DPTE: 113790941
CSCU: 111615019 111640961
PTEP: 107437062 107456521
CEL: CELE_C43F9.8(efn-2)
CBR: CBG04418(Cbr-efn-2) CBG07443(Cbr-efn-3)
BMY: Bm1_37240
LOA: LOAG_16848 LOAG_16911
NAI: NECAME_05859 NECAME_05861 NECAME_06982 NECAME_16577
TSP: Tsp_02665 Tsp_02965 Tsp_02970 Tsp_02972 Tsp_12782
LGI: LOTGIDRAFT_171062
PCAN: 112559362
CRG: 105319122
MYI: 110442241
OBI: 106874320
LAK: 106160771
NVE: 116614571 116618131 5520077
EPA: 110231756 110237655 110237673 110242003 110243699
ADF: 107327680 107328762 107329780 107330361 107333315 107344149 107344162 107351960 107355667
AMIL: 114948759 114948972 114949149 114949496 114949811 114951629 114955873 114955887 114965606 114965607 114967970
PDAM: 113682184 113684291 113684292 113684297 113684318
SPIS: 111318933 111324654 111324666 111342416 111343969
DGT: 114518384 114525734 114531031 114542462
HMG: 101241625 105846745
 » show all
Reference
PMID:8559144
  Authors
Cerretti DP, Vanden Bos T, Nelson N, Kozlosky CJ, Reddy P, Maraskovsky E, Park LS, Lyman SD, Copeland NG, Gilbert DJ, et al.
  Title
Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.
  Journal
Mol Immunol 32:1197-205 (1995)
DOI:10.1016/0161-5890(95)00108-5
  Sequence
[hsa:1948]
Reference
  Authors
Pitulescu ME, Adams RH
  Title
Eph/ephrin molecules--a hub for signaling and endocytosis.
  Journal
Genes Dev 24:2480-92 (2010)
DOI:10.1101/gad.1973910
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