KEGG ORTHOLOGY: K05473

ORTHOLOGY: K05473

Entry

K05473                      KO

Symbol

TNFSF11, RANKL, CD254

Name

tumor necrosis factor ligand superfamily member 11

Pathway

map04060

Cytokine-cytokine receptor interaction

map04064

NF-kappa B signaling pathway

map04380

Osteoclast differentiation

map04917

Prolactin signaling pathway

map04928

Parathyroid hormone synthesis, secretion and action

map05207

Chemical carcinogenesis - receptor activation

map05224

Breast cancer

map05323

Rheumatoid arthritis

Disease

H00436

Osteopetrosis

H01470

Giant cell tumor of bone

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04928 Parathyroid hormone synthesis, secretion and action
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09162 Cancer: specific types
   05224 Breast cancer
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04090 CD molecules
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Tumor necrosis fators
   K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
CD molecules [BR:ko04090]
Proteins
  K05473  CD254, TNFSF11; tumor necrosis factor (ligand) superfamily, member 11

Other DBs

GO:

0005164

Genes

HSA:	8600(TNFSF11)

PTR:	467353(TNFSF11)

PPS:	100994539(TNFSF11)

GGO:	101131644(TNFSF11)

PON:	100439883(TNFSF11)

NLE:	100599838(TNFSF11)

HMH:	116467215(TNFSF11)

MCC:	699955(TNFSF11)

MCF:	102137946(TNFSF11)

MTHB:

126940380

MNI:	105491723(TNFSF11)

CSAB:

103214344(TNFSF11)

CATY:

105587810(TNFSF11)

PANU:

101026064(TNFSF11)

TGE:	112610939(TNFSF11)

MLEU:

105535517(TNFSF11)

RRO:	104671084(TNFSF11)

RBB:	108514105(TNFSF11)

TFN:	117096667(TNFSF11)

PTEH:

111540414(TNFSF11)

CANG:

105510559(TNFSF11)

CJC:	100401379(TNFSF11)

SBQ:	101051208(TNFSF11)

CIMI:

108309685(TNFSF11)

CSYR:

103264833(TNFSF11)

MMUR:

105869318(TNFSF11)

LCAT:

123648860(TNFSF11)

PCOQ:

105813945(TNFSF11)

OGA:	100964778(TNFSF11)

MMU:	21943(Tnfsf11)

MCAL:

110309649(Tnfsf11)

MPAH:

110325778(Tnfsf11)

RNO:	117516(Tnfsf11)

MCOC:

116084439(Tnfsf11)

ANU:	117705932(Tnfsf11)

MUN:	110562414(Tnfsf11)

CGE:	100768715(Tnfsf11)

MAUA:

101827402(Tnfsf11)

PROB:

127230483(Tnfsf11)

PLEU:

114699851(Tnfsf11)

MORG:

121464236(Tnfsf11)

AAMP:

119800481(Tnfsf11)

NGI:	103751291(Tnfsf11)

HGL:	101696350(Tnfsf11)

CPOC:

100713226(Tnfsf11)

CCAN:

109700348(Tnfsf11)

DORD:

105998104(Tnfsf11)

DSP:	122112694(Tnfsf11)

PLOP:

125347869(Tnfsf11)

NCAR:

124985349

MMMA:

107140871(Tnfsf11)

OCU:

100341009

OPI:	101526376 101532341(TNFSF11)

TUP:	102487682(TNFSF11)

GVR:	103608964(TNFSF11)

CFA:	609418(TNFSF11)

CLUD:

112678837(TNFSF11)

VVP:	112928102(TNFSF11)

VLG:	121477078(TNFSF11)

NPO:	129516607(TNFSF11)

AML:	100483079(TNFSF11)

UMR:	103677566(TNFSF11)

UAH:	113251369(TNFSF11)

UAR:	123801101(TNFSF11)

ELK:

111147123

LLV:

125094634

MPUF:

101672512 101682798(TNFSF11)

MNP:	132002474(TNFSF11)

MLK:	131813956(TNFSF11)

NVS:	122907860(TNFSF11)

ORO:	101376926(TNFSF11)

EJU:	114211677(TNFSF11)

ZCA:	113920567(TNFSF11)

MLX:	118009176(TNFSF11)

NSU:	110587728(TNFSF11)

LWW:

102744110

FCA:	724036(TNFSF11)

PYU:	121013014(TNFSF11)

PCOO:

112860814(TNFSF11)

PBG:	122483032(TNFSF11)

PVIV:

125146779(TNFSF11)

LRUF:

124512581

PTG:	102954463(TNFSF11)

PPAD:

109265885(TNFSF11)

PUC:

125933815

AJU:

106971982

HHV:	120248657(TNFSF11)

BTA:	513836(TNFSF11)

BOM:	102267691(TNFSF11)

BIU:	109566677(TNFSF11)

BBUB:

102393260(TNFSF11)

BBIS:

104999126(TNFSF11)

CHX:	102176335(TNFSF11)

OAS:	100037694(TNFSF11)

BTAX:

128057835(TNFSF11)

ODA:	120883183(TNFSF11)

CCAD:

122447465(TNFSF11)

MBEZ:

129556590(TNFSF11)

SSC:	100037976(TNFSF11)

CFR:	102507742(TNFSF11)

CBAI:

105083435(TNFSF11)

CDK:	105089768(TNFSF11)

VPC:	102533548(TNFSF11)

BACU:

103002678(TNFSF11)

BMUS:

118884331(TNFSF11)

LVE:	103074658(TNFSF11)

OOR:	101284929(TNFSF11)

DLE:	111175123(TNFSF11)

PCAD:

102978976(TNFSF11)

PSIU:

116743210(TNFSF11)

NASI:

112406633(TNFSF11)

ECB:	100060254(TNFSF11)

EPZ:	103560371(TNFSF11)

EAI:	106847554(TNFSF11)

MYB:	102260756(TNFSF11)

MYD:	102751742(TNFSF11)

MMYO:

118651542(TNFSF11)

MLF:	102427077(TNFSF11)

PKL:	118730609(TNFSF11)

EFUS:

103289655(TNFSF11)

MNA:	107531354(TNFSF11)

DRO:	112311127(TNFSF11)

SHON:

118997034(TNFSF11)

AJM:	119042868(TNFSF11)

PDIC:

114508772(TNFSF11)

PHAS:

123818869(TNFSF11)

MMF:	118622793(TNFSF11)

PPAM:

129081082(TNFSF11)

HAI:	109386844(TNFSF11)

RFQ:	117021430(TNFSF11)

PALE:

102896284(TNFSF11)

PGIG:

120614450(TNFSF11)

PVP:	105298465(TNFSF11)

RAY:	107517455(TNFSF11)

MJV:	108407315(TNFSF11)

TOD:	119259662(TNFSF11)

SARA:

101547843(TNFSF11)

SETR:

126016258(TNFSF11)

LAV:	100663523(TNFSF11)

TMU:

101342165

ETF:	101659751(TNFSF11)

DNM:	101429635(TNFSF11)

MDO:	100011641(TNFSF11)

GAS:	123240037(TNFSF11)

SHR:	105750026(TNFSF11)

AFZ:

127553269

PCW:	110201421(TNFSF11)

OAA:	100076541(TNFSF11)

GGA:	428067(TNFSF11)

PCOC:

116244153(TNFSF11)

MGP:	104917524(TNFSF11)

CJO:	107308113(TNFSF11)

TPAI:

128092110(TNFSF11)

LMUT:

125685116(TNFSF11)

NMEL:

110387248(TNFSF11)

APLA:

101803149(TNFSF11)

ACYG:

106035087(TNFSF11)

CATA:

118251346(TNFSF11)

AFUL:

116501867(TNFSF11)

TGU:	100227247(TNFSF11)

LSR:	110470890(TNFSF11)

SCAN:

103812581(TNFSF11)

PMOA:

120505810(TNFSF11)

OTC:	121337314(TNFSF11)

PRUF:

121353320(TNFSF11)

GFR:	102038556(TNFSF11)

FAB:	101822088(TNFSF11)

OMA:	130255404(TNFSF11)

PHI:	102111124(TNFSF11)

PMAJ:

107212828(TNFSF11)

CCAE:

111935210(TNFSF11)

CCW:	104693175(TNFSF11)

CBRC:

103615178(TNFSF11)

ETL:	114059881(TNFSF11)

ZAB:	102064010(TNFSF11)

ACHL:

103798173(TNFSF11)

SVG:	106862463(TNFSF11)

MMEA:

130573697(TNFSF11)

HRT:	120749051(TNFSF11)

FPG:	101919009(TNFSF11)

FCH:	102050665(TNFSF11)

CLV:	102098042(TNFSF11)

EGZ:	104132030(TNFSF11)

NNI:	104010922(TNFSF11)

PCRI:

104036929(TNFSF11)

PLET:

104615248(TNFSF11)

EHS:	104516909(TNFSF11)

PCAO:

104050873(TNFSF11)

ACUN:

113480179(TNFSF11)

TALA:

104358598(TNFSF11)

PADL:

103915905(TNFSF11)

AFOR:

103895905(TNFSF11)

ACHC:

115350784(TNFSF11)

HALD:

104319076(TNFSF11)

HLE:	104837359(TNFSF11)

AGEN:

126045137

GCL:

127026989

CCRI:

104165582(TNFSF11)

CSTI:

104562176(TNFSF11)

CMAC:

104480985(TNFSF11)

MUI:	104537437(TNFSF11)

BREG:

104636927(TNFSF11)

FGA:	104079157(TNFSF11)

GSTE:

104257775(TNFSF11)

LDI:	104340678(TNFSF11)

MNB:	103776876(TNFSF11)

OHA:	104336935(TNFSF11)

NNT:	104411387(TNFSF11)

SHAB:

115603892(TNFSF11)

DPUB:

104306580(TNFSF11)

PGUU:

104470509(TNFSF11)

ACAR:

104526293(TNFSF11)

CPEA:

104391534(TNFSF11)

CVF:	104293445(TNFSF11)

RTD:	128911728(TNFSF11)

CUCA:

104056514(TNFSF11)

TEO:	104370798(TNFSF11)

BRHI:

104489276(TNFSF11)

AAM:	106489200(TNFSF11)

AROW:

112962605(TNFSF11)

NPD:	112943361(TNFSF11)

TGT:	104572592(TNFSF11)

DNE:	112982655(TNFSF11)

SCAM:

104142482(TNFSF11)

ASN:	102387902(TNFSF11)

AMJ:	102559854(TNFSF11)

CPOO:

109305514(TNFSF11)

GGN:	109302252(TNFSF11)

PSS:	102444457(TNFSF11)

CMY:	102947527(TNFSF11)

CCAY:

125637087(TNFSF11)

DCC:	119841216(TNFSF11)

CPIC:

101936501(TNFSF11)

TST:	117871596(TNFSF11)

CABI:

116817999(TNFSF11)

MRV:	120396036(TNFSF11)

ACS:	100566737(tnfsf11)

ASAO:

132771343(TNFSF11)

PVT:	110084678(TNFSF11)

SUND:

121926338(TNFSF11)

PMUR:

107283208(TNFSF11)

CTIG:

120318729(TNFSF11)

PGUT:

117667006(TNFSF11)

APRI:

131199213(TNFSF11)

PTEX:

113439469(TNFSF11)

NSS:

113429675

VKO:	123032407(TNFSF11)

PMUA:

114600094(TNFSF11)

PRAF:

128417981(TNFSF11)

ZVI:	118079346(TNFSF11)

HCG:	128351121(TNFSF11)

GJA:	107123862(TNFSF11)

STOW:

125430486(TNFSF11)

EMC:	129325960(TNFSF11)

XLA:	496322(tnfsf11.L) 733333(tnfsf11.S)

XTR:	100038074(tnfsf11)

NPR:	108790250(TNFSF11)

RTEM:

120929646(TNFSF11)

BGAR:

122932374(TNFSF11)

MUO:	115468661(TNFSF11)

GSH:	117361986(TNFSF11)

SRX:	107713713 107749039(tnfsf11)

SANH:

107661329(tnfsf11) 107688674

SGH:

CCAR:

CAUA:

AMEX:

EEE:

MZE:	101482899(tnfsf11)

ONL:

100690570

OAU:	116310490(tnfsf11)

XMA:	102231551(tnfsf11)

XCO:	114148628(tnfsf11)

PRET:

103481812(tnfsf11)

CVG:

107101899

SASA:

106575455 106582173 106582220 106586517(tnfsf11) 106592211

OTW:	112225511 112235911 112236954 112239917(tnfsf11)

OMY:	100136320 110501712(tnfsf11) 110520367 110527377

SALP:

111978065(tnfsf11) 112074051 112075152 112080705

ELS:	105016373 105019817

SFM:	108920497(tnfsf11) 108928984

PSPA:

121321280 121327682

LCM:	102363811(TNFSF11)

SPU:

115922601

HRF:

124125943

CRG:	105326163 105344501

MMER:

123526486

» show all

Reference

PMID:9367155

Authors

Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L

Title

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Journal

Nature 390:175-9 (1997)
DOI:10.1038/36593

Sequence

[hsa:8600]

LinkDB

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