KEGG   ORTHOLOGY: K05505Help
Entry
K05505                      KO                                     

Name
CXCL1_2_3, GRO
Definition
C-X-C motif chemokine 1/2/3
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04062  Chemokine signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04657  IL-17 signaling pathway
ko04668  TNF signaling pathway
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05132  Salmonella infection
ko05134  Legionellosis
ko05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
   04657 IL-17 signaling pathway
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
   04062 Chemokine signaling pathway
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
   05132 Salmonella infection
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
   05134 Legionellosis
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Chemokines
   K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
BRITE hierarchy
Genes
HSA: 2919(CXCL1) 2920(CXCL2) 2921(CXCL3)
PTR: 461255(CXCL3) 740176(CXCL2) 740567(CXCL1)
PPS: 100974886(CXCL2) 100975544(CXCL3) 100976904(CXCL1)
GGO: 101131798(CXCL1) 101133388(CXCL3) 101133748 101134092
PON: 100438959(CXCL1) 100440799(CXCL3) 100441532(CXCL2)
NLE: 100588392(CXCL3) 100592551
MCC: 100424064 574222(CXCL1) 574223(CXCL3) 702067 703390
MCF: 102117979(CXCL3) 102123272(CXCL2) 102123657(CXCL3) 102125504(CXCL1L) 102126138(CXCL1)
CSAB: 103235789(CXCL1) 103235792 103235798(CXCL3) 103236682
RRO: 104654807 104658876(CXCL1) 104658882 104658884
CJC: 100389870(CXCL2) 100400489(CXCL2) 100401955(CXCL1)
SBQ: 101048540
MMU: 14825(Cxcl1) 20310(Cxcl2) 330122(Cxcl3)
RNO: 114105(Cxcl2) 171551(Cxcl3) 81503(Cxcl1)
CGE: 100689059(Cxcl1) 100689100(Cxcl3)
HGL: 101705558(Cxcl1)
CCAN: 109691926
OCU: 100009192(GRO-G) 100009245(GRO-A) 100328583(GRO-B) 100354804
TUP: 102467686
AML: 100463732(CXCL2)
UMR: 103665389
BTA: 281212(GRO1) 281214(CXCL2) 613667(CXCL3)
SSC: 414904(CXCL2)
CDK: 105091368
ECB: 100034121(CXCL1) 100056258(MIP-2BETA) 100233237(CXCL2)
MNA: 107534487
DRO: 112319915(CXCL1) 112320502
LAV: 100665129
SHR: 100915440
CCAE: 111929440
CLV: 110359497
PSS: 102459718
PBI: 103060149
EEE: 113589772
XCO: 114157834
PRET: 103475946
SASA: 106608883
ELS: 105014543
SFM: 108918077
LCM: 102351965
CMK: 103183735
VG: 25026530(UL146D)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Modi WS, Yoshimura T
  Title
Isolation of novel GRO genes and a phylogenetic analysis of the CXC chemokine subfamily in mammals.
  Journal
Mol Biol Evol 16:180-93 (1999)
DOI:10.1093/oxfordjournals.molbev.a026101
Reference
PMID:2970963
  Authors
Richmond A, Balentien E, Thomas HG, Flaggs G, Barton DE, Spiess J, Bordoni R, Francke U, Derynck R
  Title
Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.
  Journal
EMBO J 7:2025-33 (1988)
  Sequence
[hsa:2919]
Reference
PMID:2078213
  Authors
Iida N, Grotendorst GR
  Title
Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue.
  Journal
Mol Cell Biol 10:5596-9 (1990)
DOI:10.1128/MCB.10.10.5596
  Sequence
[hsa:2920]
Reference
PMID:2217207
  Authors
Haskill S, Peace A, Morris J, Sporn SA, Anisowicz A, Lee SW, Smith T, Martin G, Ralph P, Sager R
  Title
Identification of three related human GRO genes encoding cytokine functions.
  Journal
Proc Natl Acad Sci U S A 87:7732-6 (1990)
DOI:10.1073/pnas.87.19.7732
  Sequence
[hsa:2921]
LinkDB All DBs

DBGET integrated database retrieval system