KEGG   ORTHOLOGY: K05547
Entry
K05547                      KO                                     

Name
THRA, NR1A1
Definition
thyroid hormone receptor alpha
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04919  Thyroid hormone signaling pathway
Disease
H00250  Congenital nongoitrous hypothyroidism (CHNG)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05547  THRA, NR1A1; thyroid hormone receptor alpha
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K05547  THRA, NR1A1; thyroid hormone receptor alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K05547  THRA, NR1A1; thyroid hormone receptor alpha
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K05547  THRA, NR1A1; thyroid hormone receptor alpha
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    K05547  THRA, NR1A1; thyroid hormone receptor alpha
Nuclear receptors [BR:ko03310]
 1. Thyroid hormone like
  1A. Thyroid hormone receptor (THR)
   K05547  THRA, NR1A1; thyroid hormone receptor alpha
Genes
HSA: 7067(THRA)
PTR: 101057334(THRA)
PPS: 100971326(THRA)
GGO: 101143950(THRA)
PON: 100440414(THRA)
NLE: 105737897(THRA)
MCC: 699650(THRA)
MCF: 101865809(THRA)
CSAB: 103243521(THRA)
RRO: 104655114(THRA)
RBB: 108527798(THRA)
CJC: 100407912(THRA)
SBQ: 101039683
MMU: 21833(Thra)
MCAL: 110305117(Thra)
MPAH: 110332558(Thra)
RNO: 81812(Thra)
MUN: 110558497(Thra)
CGE: 100770653(Thra)
NGI: 103731115(Thra)
HGL: 101726699(Thra)
CCAN: 109694429(Thra)
OCU: 100303772(THRA)
TUP: 102494660(THRA)
CFA: 403601(THRA)
VVP: 112917772(THRA)
AML: 100483871(THRA)
UMR: 103661702(THRA)
UAH: 113265499(THRA)
ORO: 101384863(THRA)
ELK: 111151319
FCA: 101095056(THRA)
PTG: 102966654(THRA)
PPAD: 109247439(THRA)
AJU: 106980522(THRA)
BTA: 532621(THRA)
BOM: 102272957(THRA)
BIU: 109573677(THRA)
BBUB: 102407600(THRA)
CHX: 102186338(THRA)
OAS: 443446(THRA)
SSC: 397387(THRA)
CFR: 102515304(THRA)
CDK: 105099028(THRA)
BACU: 103006669(THRA)
LVE: 103079896(THRA)
OOR: 101288193(THRA)
DLE: 111166480(THRA)
PCAD: 102986372(THRA)
ECB: 100054511(THRA)
EPZ: 103550173(THRA)
EAI: 106826372(THRA)
MYB: 102263074(THRA)
MYD: 102753452(THRA)
MNA: 107529001(THRA)
HAI: 109380770(THRA)
DRO: 112316188(THRA)
PALE: 102881243(THRA)
RAY: 107520667(THRA)
MJV: 108385158(THRA)
LAV: 100664480(THRA)
TMU: 101360413
MDO: 100016503(THRA)
SHR: 100913683(THRA)
PCW: 110215669(THRA)
OAA: 100079871(THRA)
GGA: 396251(THRA)
CJO: 107325239(THRA)
NMEL: 110388679(THRA)
TGU: 115490653(THRA)
LSR: 110471871(THRA)
SCAN: 115484564(THRA)
GFR: 102044997(THRA)
FAB: 101815750(THRA)
PHI: 102110541(THRA)
PMAJ: 107215324(THRA)
CCAE: 111940008(THRA)
CCW: 104697793(THRA)
ETL: 114070873(THRA)
FPG: 101913188(THRA)
CLV: 102095479(THRA)
NNI: 104012331(THRA)
ASN: 102367768(THRA)
AMJ: 102562427(THRA)
PSS: 102459299(THRA)
CMY: 102948277(THRA)
CPIC: 101949057(THRA)
ACS: 100561253(thra)
PVT: 110085571(THRA)
PBI: 103064892(THRA)
PMUR: 107295777 107303020(THRA)
TSR: 106548059 106555336(THRA)
PMUA: 114583658(THRA)
GJA: 107108823(THRA)
XLA: 108702484(TRalphaB) 397942(thra.L)
XTR: 734136(thra)
NPR: 108797874
DRE: 30670(thraa) 558427(thrab)
IPU: 108273906
PHYP: 113527477
OLA: 100049275(thra) 101167294
HCQ: 109506918 109530209(thra)
SASA: 100136523(tr-alpha) 106579329 106583871 106589304(TR-alpha)
PKI: 111845119
LCM: 102345437(THRA)
CMK: 103172030
RTP: 109913410(thra)
PVM: 113826050
BMY: Bm1_14435
LAK: 106171104
 » show all
Reference
PMID:9447705
  Authors
Essner JJ, Breuer JJ, Essner RD, Fahrenkrug SC, Hackett PB Jr
  Title
The zebrafish thyroid hormone receptor alpha 1 is expressed during early embryogenesis and can function in transcriptional repression.
  Journal
Differentiation 62:107-17 (1997)
DOI:10.1046/j.1432-0436.1997.6230107.x
  Sequence
[dre:30670]
Reference
  Authors
Bassett JH, Harvey CB, Williams GR
  Title
Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions.
  Journal
Mol Cell Endocrinol 213:1-11 (2003)
DOI:10.1016/j.mce.2003.10.033
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