KEGG   ORTHOLOGY: K05689
Entry
K05689                      KO                                     

Symbol
CDH1, CDHE, CD324
Name
cadherin 1, type 1, E-cadherin
Pathway
map04015  Rap1 signaling pathway
map04371  Apelin signaling pathway
map04390  Hippo signaling pathway
map04514  Cell adhesion molecules
map04520  Adherens junction
map05100  Bacterial invasion of epithelial cells
map05200  Pathways in cancer
map05213  Endometrial cancer
map05216  Thyroid cancer
map05218  Melanoma
map05219  Bladder cancer
map05226  Gastric cancer
Disease
H00018  Gastric cancer
H00025  Penile cancer
H00032  Thyroid cancer
H00054  Nasopharyngeal cancer
H02474  Blepharocheilodontic syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   04390 Hippo signaling pathway
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   04371 Apelin signaling pathway
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  09162 Cancer: specific types
   05226 Gastric cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05216 Thyroid cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05218 Melanoma
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05219 Bladder cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05213 Endometrial cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   04090 CD molecules
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Other centriole associated proteins
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
Cell adhesion molecules [BR:ko04515]
 Cadherins
  Major cadherins
   K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
CD molecules [BR:ko04090]
 Proteins
  K05689  CD324, CDH1; cadherin 1, type 1, E-cadherin (epithelial)
Genes
HSA: 999(CDH1)
PTR: 468009(CDH1)
PPS: 100989112(CDH1)
GGO: 101145191(CDH1)
PON: 100174439(CDH1)
NLE: 100596627(CDH1)
MCC: 704387(CDH1)
MCF: 102143513(CDH1)
CSAB: 103233229(CDH1)
CATY: 105582144(CDH1)
PANU: 101005609(CDH1)
RRO: 104655589(CDH1)
RBB: 108514542(CDH1)
TFN: 117087958(CDH1)
PTEH: 111541390(CDH1)
CJC: 100398679(CDH1)
SBQ: 101049706(CDH1)
MMUR: 105858954(CDH1)
MMU: 12550(Cdh1)
MCAL: 110300286(Cdh1)
MPAH: 110337432(Cdh1)
RNO: 83502(Cdh1)
MCOC: 116070104(Cdh1)
MUN: 110545977(Cdh1)
CGE: 100758185(Cdh1)
PLEU: 114683440
NGI: 103734864(Cdh1)
HGL: 101719565(Cdh1)
CCAN: 109693763(Cdh1)
OCU: 100356548(CDH1)
TUP: 102499381(CDH1)
CFA: 442858(CDH1) 489647
VVP: 112924654 112929524(CDH1)
VLG: 121500345(CDH1) 121500539
AML: 100475573(CDH1) 105240970
UMR: 103673623(CDH1) 103673974
UAH: 113252413(CDH1)
ORO: 101375608(CDH1)
MPUF: 101680359 101682346(CDH1)
EJU: 114201853(CDH1)
MLX: 118023633(CDH1)
FCA: 101095391(CDH1)
PYU: 121009705(CDH1)
PBG: 122495148(CDH1)
PTG: 102949516(CDH1) 102971532
PPAD: 109270716(CDH1)
AJU: 106972406(CDH1)
HHV: 120225176(CDH1)
BTA: 282637(CDH1)
BOM: 102284702(CDH1)
BIU: 109572856
BBUB: 102400153(CDH1)
CHX: 102170451(CDH1)
OAS: 101119747(CDH1)
ODA: 120872702(CDH1)
CCAD: 122421517(CDH1)
SSC: 100048953(CDH1)
CFR: 102518832
CBAI: 105074863(CDH1)
CDK: 105088409(CDH1)
BACU: 102999370(CDH1)
LVE: 103073913(CDH1)
OOR: 101288322(CDH1)
DLE: 111179595(CDH1)
PCAD: 102988252(CDH1)
ECB: 100066844(CDH1)
EPZ: 103549722(CDH1)
EAI: 106822455(CDH1)
MYB: 102243128(CDH1)
MYD: 102763531 102771627(CDH1)
MMYO: 118674502(CDH1)
MNA: 107527895(CDH1)
HAI: 109389333(CDH1)
DRO: 112300798(CDH1)
SHON: 118983812(CDH1)
AJM: 119061846(CDH1)
MMF: 118639271(CDH1)
PALE: 102886394(CDH1)
PGIG: 120593865(CDH1)
RAY: 107520648(CDH1)
MJV: 108404941(CDH1)
TOD: 119248990(CDH1)
LAV: 100659456(CDH1)
TMU: 101350182
MDO: 100027800(CDH1)
SHR: 100920258(CDH1)
PCW: 110210266(CDH1)
OAA: 100079609(CDH1)
GGA: 415860(CDH1)
MGP: 104913062
NMEL: 110404211
APLA: 101794572
ACYG: 106046592
TGU: 100232461
LSR: 110468793
SCAN: 103816905(CDH1)
PMOA: 120496239
OTC: 121333869
GFR: 102040110(CDH1)
FAB: 101805985(CDH1)
PHI: 102111961 102112140(CDH1)
PMAJ: 107209925(CDH1)
CCAE: 111944815
CCW: 104691942
ETL: 114067998(CDH1)
CLV: 110354868(CDH1)
ACUN: 113484597
AAM: 106487432
AROW: 112975127(CDH1)
NPD: 112947506
DNE: 112994996(CDH1)
ASN: 102380182(CDH1)
AMJ: 102576711 106737158(CDH1)
CPOO: 109310379(CDH1)
GGN: 109289251(CDH1)
CABI: 116819568(CDH1)
ACS: 100558436(cdh1)
PVT: 110076337(CDH1) 110076338
PBI: 103048275(CDH1)
TSR: 106542216
PGUT: 117671054
PMUA: 114602086(CDH1) 114602091(CDH3)
XLA: 100337618(cdh1.S) 108714071(cdh1.L) 394290(cdh3.S) 594865(cdh3.L)
XTR: 100485633(cdh3) 779546(cdh1)
DRE: 114424(cdh1) 567602(cdh31)
IPU: 108259210
PHYP: 113546740
EEE: 113575713(cdh1) 113575719
NCC: 104965112
ELY: 117248092 117248591 117262549(si:dkey-30c15.12)
ECRA: 117941851 117960927(cdh31)
GAT: 120820444
CUD: 121514546
CTUL: 119771883 119792671(cdh31) 119792672 119793009(si:dkey-30c15.12)
NFU: 107397122(cdh1)
CSEM: 103387719
XGL: 120793396 120796800(cdh1)
HCQ: 109523134
MALB: 109960058(cdh1)
ELS: 105016989
PKI: 111832945
LOC: 102683213(cdh1) 102694645
CMK: 103175998
RTP: 109937057(cdh1)
 » show all
Reference
PMID:8459805
  Authors
Bussemakers MJ, van Bokhoven A, Mees SG, Kemler R, Schalken JA
  Title
Molecular cloning and characterization of the human E-cadherin cDNA.
  Journal
Mol Biol Rep 17:123-8 (1993)
DOI:10.1007/bf00996219
  Sequence
[hsa:999]
Reference
  Authors
Agiostratidou G, Muros RM, Shioi J, Marambaud P, Robakis NK
  Title
The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors.
  Journal
J Neurochem 96:1182-8 (2006)
DOI:10.1111/j.1471-4159.2005.03616.x
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