KEGG   ORTHOLOGY: K05717Help
Entry
K05717                      KO                                     

Name
FN1
Definition
fibronectin 1
Pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04810  Regulation of actin cytoskeleton
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05100  Bacterial invasion of epithelial cells
ko05135  Yersinia infection
ko05146  Amoebiasis
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05222  Small cell lung cancer
Disease
H01260  Glomerulopathy with fibronectin deposits
H02185  Spondylometaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K05717  FN1; fibronectin 1
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K05717  FN1; fibronectin 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05717  FN1; fibronectin 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05717  FN1; fibronectin 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05717  FN1; fibronectin 1
   05205 Proteoglycans in cancer
    K05717  FN1; fibronectin 1
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K05717  FN1; fibronectin 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K05717  FN1; fibronectin 1
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05717  FN1; fibronectin 1
   05100 Bacterial invasion of epithelial cells
    K05717  FN1; fibronectin 1
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K05717  FN1; fibronectin 1
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K05717  FN1; fibronectin 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05717  FN1; fibronectin 1
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K05717  FN1; fibronectin 1
   00536 Glycosaminoglycan binding proteins
    K05717  FN1; fibronectin 1
Membrane trafficking [BR:ko04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    K05717  FN1; fibronectin 1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   K05717  FN1; fibronectin 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   K05717  FN1; fibronectin 1
BRITE hierarchy
Genes
HSA: 2335(FN1)
PTR: 459926(FN1)
PPS: 100992555(FN1)
GGO: 101138168(FN1)
PON: 100449704(FN1)
NLE: 100601303(FN1)
MCC: 613269(FN1)
MCF: 102119232(FN1)
CSAB: 103217800(FN1)
RRO: 104669238(FN1)
RBB: 108543178(FN1)
CJC: 100405983(FN1)
SBQ: 101045340(FN1)
MMU: 14268(Fn1)
MCAL: 110283623(Fn1)
MPAH: 110321151(Fn1)
RNO: 25661(Fn1)
MUN: 110557288(Fn1)
CGE: 100751189(Fn1)
NGI: 103727691(Fn1)
HGL: 101718570(Fn1)
CCAN: 109697804(Fn1) 109702876
OCU: 100328589(FN1)
TUP: 102490245(FN1)
CFA: 403845(FN1)
VVP: 112922455(FN1)
AML: 100464134(FN1)
UMR: 103662788(FN1)
UAH: 113250491(FN1)
ORO: 101365197(FN1)
FCA: 101081746(FN1)
PTG: 102970250(FN1)
AJU: 106970125(FN1)
BTA: 280794(FN1)
BOM: 102280180(FN1)
BBUB: 102410593(FN1)
PHD: 102336627(FN1)
CHX: 102182645(FN1)
OAS: 100216462(FN1)
SSC: 397620(FN1)
CFR: 102518759(FN1)
CDK: 105086605(FN1)
BACU: 103018975(FN1)
LVE: 103084224(FN1)
OOR: 101275475(FN1)
DLE: 111171803(FN1)
ECB: 100034189(FN1)
EPZ: 103563053(FN1)
EAI: 106832715(FN1)
MYB: 102244892(FN1)
MYD: 102753951(FN1)
MNA: 107524737(FN1)
HAI: 109380590(FN1)
RSS: 109445065(FN1)
DRO: 112307828(FN1)
PALE: 102891509(FN1)
LAV: 100667853(FN1)
TMU: 101361092
MDO: 100014118(FN1)
SHR: 100927509(FN1)
PCW: 110219415(FN1)
OAA: 100078116(FN1)
GGA: 396133(FN1)
MGP: 100551213(FN1)
CJO: 107316471(FN1)
APLA: 101800175(FN1) 113840895
ACYG: 106034457(FN1)
TGU: 100231676(FN1)
LSR: 110474100(FN1)
SCAN: 103814579(FN1)
GFR: 102039500(FN1)
FAB: 101807963(FN1)
PHI: 102104961(FN1)
PMAJ: 107207628(FN1)
CCAE: 111931693(FN1)
CCW: 104694587(FN1)
ETL: 114060672(FN1)
FPG: 101911302(FN1)
FCH: 102054264(FN1)
CLV: 102090641(FN1)
EGZ: 104124152(FN1)
NNI: 104010144(FN1)
ACUN: 113482082(FN1)
AAM: 106492397(FN1)
ASN: 102381879(FN1)
AMJ: 102569824(FN1)
PSS: 102450093(FN1)
CMY: 102932170(FN1)
CPIC: 101942436 101948945(FN1)
ACS: 100563512(fn1)
PVT: 110081893(FN1)
PBI: 103048603(FN1)
PMUR: 107292554(FN1)
GJA: 107121182(FN1)
XLA: 397744(fn1.S)
XTR: 595087(fn1)
NPR: 108789839(FN1)
DRE: 100005469(fn1a)
TRU: 101061998 101071818(fn1)
OLA: 100529198(fn1) 101159085
PRET: 103460487 103462008(fn1)
NFU: 107381665(fn1) 107390187
OTW: 112225680(fn1) 112239140
SALP: 112071311
ELS: 105019714(fn1) 105030358
PKI: 111840678(fn1) 111858354
LCM: 102360478 102367537(FN1)
CMK: 103176556(fn1)
CIN: 100180297
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kay RA, Ellis IR, Jones SJ, Perrier S, Florence MM, Schor AM, Schor SL
  Title
The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3'-untranslated region-dependent nuclear sequestration of its precursor messenger RNA.
  Journal
Cancer Res 65:10742-9 (2005)
DOI:10.1158/0008-5472.CAN-05-2038
  Sequence
[hsa:2335]
Reference
  Authors
Yi M, Ruoslahti E
  Title
A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis.
  Journal
Proc Natl Acad Sci U S A 98:620-4 (2001)
DOI:10.1073/pnas.98.2.620
Reference
PMID:3031656
  Authors
Dean DC, Bowlus CL, Bourgeois S
  Title
Cloning and analysis of the promotor region of the human fibronectin gene.
  Journal
Proc Natl Acad Sci U S A 84:1876-80 (1987)
DOI:10.1073/pnas.84.7.1876
  Sequence
[hsa:2335]
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