KEGG   ORTHOLOGY: K05871
Entry
K05871                      KO                                     

Name
PTK2B, FAK2
Definition
focal adhesion kinase 2 [EC:2.7.10.2]
Pathway
ko04020  Calcium signaling pathway
ko04062  Chemokine signaling pathway
ko04072  Phospholipase D signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04670  Leukocyte transendothelial migration
ko04912  GnRH signaling pathway
ko05135  Yersinia infection
ko05161  Hepatitis B
ko05163  Human cytomegalovirus infection
ko05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04072 Phospholipase D signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04670 Leukocyte transendothelial migration
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04062 Chemokine signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
  09152 Endocrine system
   04912 GnRH signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   05161 Hepatitis B
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   05163 Human cytomegalovirus infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05871  PTK2B, FAK2; focal adhesion kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05871  PTK2B, FAK2; focal adhesion kinase 2
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  FAK family
   K05871  PTK2B, FAK2; focal adhesion kinase 2
Other DBs
GO: 0004715
Genes
HSA: 2185(PTK2B)
PTR: 464073(PTK2B)
PPS: 100991936(PTK2B)
GGO: 101135800(PTK2B)
PON: 100174613(PTK2B)
NLE: 100599503(PTK2B)
MCC: 712787(PTK2B)
MCF: 102130539(PTK2B)
CSAB: 103215524(PTK2B)
RRO: 104673947(PTK2B)
RBB: 108537591(PTK2B)
CJC: 100404210(PTK2B)
SBQ: 101032561(PTK2B)
MMU: 19229(Ptk2b)
MCAL: 110308944(Ptk2b)
MPAH: 110325924(Ptk2b)
RNO: 50646(Ptk2b)
MUN: 110559230(Ptk2b)
CGE: 100758086(Ptk2b)
NGI: 103730003(Ptk2b)
HGL: 101714384(Ptk2b)
CCAN: 109698054(Ptk2b)
OCU: 100342358(PTK2B)
TUP: 102481841(PTK2B)
CFA: 486102(PTK2B)
VVP: 112926788(PTK2B)
AML: 100478801(PTK2B)
UMR: 103675966(PTK2B)
UAH: 113269957(PTK2B)
ORO: 101373391(PTK2B)
ELK: 111153692
FCA: 101091691(PTK2B)
PTG: 102955963(PTK2B)
PPAD: 109262338(PTK2B)
AJU: 106973108(PTK2B)
BTA: 541008(PTK2B)
BOM: 102266592(PTK2B)
BIU: 109563157(PTK2B)
BBUB: 102411722(PTK2B)
CHX: 102184810(PTK2B)
OAS: 101106906(PTK2B)
SSC: 100157507(PTK2B)
CFR: 102520664(PTK2B)
CDK: 105102240(PTK2B)
BACU: 103016023(PTK2B)
LVE: 103083166(PTK2B)
OOR: 101281402(PTK2B)
DLE: 111185408(PTK2B)
PCAD: 102995810(PTK2B)
ECB: 100054547(PTK2B)
EPZ: 103550428(PTK2B)
EAI: 106832511(PTK2B)
MYB: 102256791(PTK2B)
MYD: 102756394(PTK2B)
MNA: 107538557(PTK2B)
HAI: 109379535(PTK2B)
DRO: 112312413(PTK2B)
PALE: 102886432(PTK2B)
RAY: 107515459(PTK2B)
MJV: 108394326(PTK2B)
LAV: 100667505(PTK2B)
TMU: 101354947
MDO: 100025175(PTK2B)
SHR: 100923387(PTK2B)
PCW: 110206529(PTK2B)
OAA: 100085161(PTK2B)
GGA: 421998(PTK2B)
MGP: 100549921(PTK2B)
CJO: 107312386(PTK2B)
NMEL: 110395785(PTK2B)
APLA: 101792285(PTK2B)
ACYG: 106049520(PTK2B)
LSR: 110477410(PTK2B)
FAB: 101806020(PTK2B)
PHI: 102099730(PTK2B)
PMAJ: 107199198
CCAE: 111927477(PTK2B)
FPG: 101919541(PTK2B)
FCH: 102058792(PTK2B)
CLV: 102085172(PTK2B)
EGZ: 104132028(PTK2B)
NNI: 104014715(PTK2B)
ACUN: 113478314(PTK2B)
AAM: 106486362(PTK2B)
ASN: 102383255(PTK2B)
AMJ: 102569140(PTK2B)
PSS: 102461932(PTK2B)
CMY: 102944545(PTK2B)
CPIC: 101946809(PTK2B)
ACS: 100563957(ptk2b)
PVT: 110089495(PTK2B)
PBI: 103053129(PTK2B)
PMUR: 107293495(PTK2B)
TSR: 106543337
PMUA: 114594952(PTK2B)
GJA: 107111937(PTK2B)
XLA: 108717254(ptk2b.L) 108718305(ptk2b.S)
XTR: 496459(ptk2b)
NPR: 108801309
DRE: 245950(ptk2bb) 557258(ptk2ba)
SRX: 107707077 107733482(ptk2b)
SANH: 107653750 107692419 107697310 107701495
SGH: 107552084(ptk2b) 107563684 107589060 107594075
CCAR: 109103027 109106793(ptk2b) 109113399
IPU: 108258133 108270138
PHYP: 113538681(ptk2b) 113545212
AMEX: 103031863 103036889(ptk2b)
EEE: 113572664(ptk2b) 113573003
TRU: 101066596(ptk2b) 101067972
TNG: GSTEN00027121G001 GSTEN00030312G001
LCO: 104922431(ptk2b) 104929121
NCC: 104964448(ptk2b)
MZE: 101466145 101469888(ptk2b)
ONL: 100691138(ptk2b) 100702843
OLA: 101166779 101168007(ptk2b)
XMA: 102220254(ptk2b) 102237728
XCO: 114137677 114158618(ptk2b)
PRET: 103457606 103475221
CVG: 107083800(ptk2b) 107092212
NFU: 107380902 107397038(ptk2b)
KMR: 108242464(ptk2bb) 108244129
ALIM: 106525285(ptk2b) 106529652
AOCE: 111585687 111587153(ptk2b)
CSEM: 103389360 103398680
POV: 109636011 109640090
LCF: 108892923 108895601
SDU: 111237992 111239921
SLAL: 111652662 111665302
HCQ: 109520887 109524920(ptk2b)
BPEC: 110166006 110175523(ptk2b)
MALB: 109960575 109970009
SASA: 106571025(ptk2b) 106603693 106608317
OTW: 112262237
ELS: 105007684 105028736
SFM: 108924101 108934847
PKI: 111841315 111857950
LCM: 102364762(PTK2B)
OVI: T265_13813
EPA: 110254117
 » show all
Reference
PMID:7544443
  Authors
Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J
  Title
Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions.
  Journal
Nature 376:737-45 (1995)
DOI:10.1038/376737a0
  Sequence
[hsa:2185]
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