KEGG   ORTHOLOGY: K06472
Entry
K06472                      KO                                     

Name
FCGR2A, CD32
Definition
low affinity immunoglobulin gamma Fc receptor II-a
Pathway
ko04145  Phagosome
ko04380  Osteoclast differentiation
ko04611  Platelet activation
ko04666  Fc gamma R-mediated phagocytosis
ko05130  Pathogenic Escherichia coli infection
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05171  Coronavirus disease - COVID-19
ko05322  Systemic lupus erythematosus
Disease
H00080  Systemic lupus erythematosus
H01360  Allergic rhinitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04666 Fc gamma R-mediated phagocytosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05135 Yersinia infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05150 Staphylococcus aureus infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05152 Tuberculosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Fc receptors
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
CD molecules [BR:ko04090]
 Proteins
  K06472  CD32a, FCGR2A; Fc fragment of IgG, low affinity IIa, receptor for (CD32)
Other DBs
GO: 0019770
Genes
HSA: 2212(FCGR2A)
PTR: 107973075 450194(FCGR2A)
PPS: 100991644(FCGR2A)
GGO: 101130688(FCGR2A)
PON: 100455333(FCGR2A)
NLE: 101176530(FCGR2A)
MCC: 719996(FCGR2A)
MCF: 102143568(FCGR2A)
CSAB: 103223676(FCGR2A)
RRO: 104669518(FCGR2A)
RBB: 108542586(FCGR2A)
CJC: 100387574(FCGR2A)
SBQ: 101040113(FCGR2A)
MCAL: 110288995
MPAH: 110321588
RNO: 498276
MUN: 110554429(Fcgr2a)
CGE: 103161891
NGI: 103746769(Fcgr2a)
HGL: 101700630(Fcgr2a)
CCAN: 109693506(Fcgr2a)
OCU: 100338413(FCGR2A)
BOM: 102274112
BIU: 109578180
OAS: 101106730
PCAD: 112062432
EPZ: 103540857 103540858(FCGR2A)
EAI: 106831113 106831115(FCGR2A)
MYB: 102263991
PALE: 102879478
RAY: 107502475
LAV: 104846329(FCGR2A)
TMU: 101350744
SANH: 107686749
TRU: 101072820
OLA: 105356322
XMA: 111611255
KMR: 112449806
SDU: 111239865
BPEC: 110172767
SASA: 106571983
ELS: 109615278
 » show all
Reference
PMID:2824655
  Authors
Stuart SG, Trounstine ML, Vaux DJ, Koch T, Martens CL, Mellman I, Moore KW
  Title
Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).
  Journal
J Exp Med 166:1668-84 (1987)
DOI:10.1084/jem.166.6.1668
  Sequence
[hsa:2212]
Reference
  Authors
Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD
  Title
Structural recognition and functional activation of FcgammaR by innate pentraxins.
  Journal
Nature 456:989-92 (2008)
DOI:10.1038/nature07468
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