KEGG   ORTHOLOGY: K06484Help
Entry
K06484                      KO                                     

Name
ITGA5, CD49e
Definition
integrin alpha 5
Pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04640  Hematopoietic cell lineage
ko04810  Regulation of actin cytoskeleton
ko05100  Bacterial invasion of epithelial cells
ko05131  Shigellosis
ko05133  Pertussis
ko05135  Yersinia infection
ko05165  Human papillomavirus infection
ko05168  Herpes simplex virus 1 infection
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K06484  ITGA5, CD49e; integrin alpha 5
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06484  ITGA5, CD49e; integrin alpha 5
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06484  ITGA5, CD49e; integrin alpha 5
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06484  ITGA5, CD49e; integrin alpha 5
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K06484  ITGA5, CD49e; integrin alpha 5
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06484  ITGA5, CD49e; integrin alpha 5
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K06484  ITGA5, CD49e; integrin alpha 5
   05205 Proteoglycans in cancer
    K06484  ITGA5, CD49e; integrin alpha 5
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K06484  ITGA5, CD49e; integrin alpha 5
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06484  ITGA5, CD49e; integrin alpha 5
   05414 Dilated cardiomyopathy (DCM)
    K06484  ITGA5, CD49e; integrin alpha 5
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K06484  ITGA5, CD49e; integrin alpha 5
   05135 Yersinia infection
    K06484  ITGA5, CD49e; integrin alpha 5
   05133 Pertussis
    K06484  ITGA5, CD49e; integrin alpha 5
   05100 Bacterial invasion of epithelial cells
    K06484  ITGA5, CD49e; integrin alpha 5
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K06484  ITGA5, CD49e; integrin alpha 5
   05165 Human papillomavirus infection
    K06484  ITGA5, CD49e; integrin alpha 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06484  ITGA5, CD49e; integrin alpha 5
   04515 Cell adhesion molecules
    K06484  ITGA5, CD49e; integrin alpha 5
   04090 CD molecules
    K06484  ITGA5, CD49e; integrin alpha 5
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06484  ITGA5, CD49e; integrin alpha 5
Cell adhesion molecules [BR:ko04515]
 Integrins
  Integrin alpha subunits
   K06484  ITGA5, CD49e; integrin alpha 5
CD molecules [BR:ko04090]
 Proteins
  K06484  CD49e, ITGA5; integrin, alpha 5
BRITE hierarchy
Genes
HSA: 3678(ITGA5)
PTR: 451958(ITGA5)
PPS: 100968295(ITGA5)
GGO: 101134285(ITGA5)
PON: 100453984(ITGA5)
NLE: 100606925(ITGA5)
MCC: 574315(ITGA5)
MCF: 102114969(ITGA5)
CSAB: 103238438(ITGA5)
RRO: 104670562(ITGA5)
RBB: 108514611(ITGA5)
CJC: 100386674(ITGA5)
SBQ: 101043820(ITGA5)
MMU: 16402(Itga5)
MCAL: 110310456(Itga5)
MPAH: 110334621(Itga5)
RNO: 315346(Itga5)
MUN: 110557599(Itga5)
CGE: 100768174(Itga5)
NGI: 103738966(Itga5)
HGL: 101714885(Itga5)
CCAN: 109686653(Itga5)
OCU: 100009172(ITGA5)
TUP: 102467775(ITGA5)
CFA: 486493(ITGA5)
VVP: 112911311(ITGA5)
AML: 100479433(ITGA5)
UMR: 103675680(ITGA5)
UAH: 113257516(ITGA5)
ORO: 101380023(ITGA5)
FCA: 101093870(ITGA5)
PTG: 102959936(ITGA5)
AJU: 106989320(ITGA5)
BTA: 281873(ITGA5)
BOM: 102276200(ITGA5)
BIU: 109558343(ITGA5)
BBUB: 102404538(ITGA5)
PHD: 102337753(ITGA5)
CHX: 102176587(ITGA5)
OAS: 443140(ITGA5)
SSC: 100155091(ITGA5)
CFR: 102507691(ITGA5)
CDK: 105101003(ITGA5)
BACU: 103011640(ITGA5)
LVE: 103074553(ITGA5)
OOR: 101275353(ITGA5)
DLE: 111173917(ITGA5)
ECB: 100064655(ITGA5)
EPZ: 103563237(ITGA5)
EAI: 106828260(ITGA5)
MYB: 102255900(ITGA5)
MNA: 107541067(ITGA5)
HAI: 109391860(ITGA5)
RSS: 109443711(ITGA5)
DRO: 112318448(ITGA5)
PALE: 102889111(ITGA5)
LAV: 100676951(ITGA5)
TMU: 101340808
SHR: 100923187(ITGA5)
PCW: 110194038(ITGA5)
OAA: 100090507(ITGA5)
PHI: 102111964(ITGA5)
FPG: 101923738(ITGA5)
FCH: 102047845(ITGA5)
ASN: 102382434(ITGA5)
AMJ: 102563393(ITGA5)
PSS: 102445917(ITGA5)
CMY: 102942186(ITGA5)
CPIC: 101936839(ITGA5)
ACS: 100566243(itga5)
PVT: 110071758(ITGA5)
PBI: 103062319(ITGA5)
PMUR: 107288179(ITGA5)
GJA: 107119049(ITGA5)
XLA: 394366(itga5.L) 397842(itga5.S)
XTR: 100492002(itga5)
NPR: 108797346(ITGA5)
DRE: 386787(itga5)
IPU: 108275658(itga5)
PHYP: 113530454(itga5)
AMEX: 103025198(itga5)
EEE: 113576413(itga5)
PRET: 103465419
PKI: 111851704(itga5)
LCM: 102364268
CMK: 103189944
AQU: 105312393
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2958481
  Authors
Argraves WS, Suzuki S, Arai H, Thompson K, Pierschbacher MD, Ruoslahti E
  Title
Amino acid sequence of the human fibronectin receptor.
  Journal
J Cell Biol 105:1183-90 (1987)
DOI:10.1083/jcb.105.3.1183
  Sequence
[hsa:3678]
Reference
  Authors
Weigel-Kelley KA, Yoder MC, Srivastava A
  Title
Alpha5beta1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of beta1 integrin for viral entry.
  Journal
Blood 102:3927-33 (2003)
DOI:10.1182/blood-2003-05-1522
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