KEGG   ORTHOLOGY: K06744Help
Entry
K06744                      KO                                     

Name
PDCD1, PD1, CD279
Definition
programmed cell death protein 1
Pathway
ko04514  Cell adhesion molecules (CAMs)
ko04660  T cell receptor signaling pathway
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Disease
H00080  Systemic lupus erythematosus
H01490  Multiple sclerosis
H01812  Rasmussen encephalitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K06744  PDCD1, PD1, CD279; programmed cell death protein 1
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K06744  PDCD1, PD1, CD279; programmed cell death protein 1
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K06744  PDCD1, PD1, CD279; programmed cell death protein 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06744  PDCD1, PD1, CD279; programmed cell death protein 1
CD molecules [BR:ko04090]
 Proteins
  K06744  CD279, PDCD1; programmed cell death 1
BRITE hierarchy
Genes
HSA: 5133(PDCD1)
PTR: 748796(PDCD1)
GGO: 101139883(PDCD1)
PON: 100462318(PDCD1)
NLE: 100596406(PDCD1)
MCC: 100135775(PDCD1)
MCF: 102123659(PDCD1)
CSAB: 103218252(PDCD1)
RRO: 104673072(PDCD1)
RBB: 108522055(PDCD1)
CJC: 100400173(PDCD1)
SBQ: 101044440(PDCD1)
MMU: 18566(Pdcd1)
MCAL: 110303426(Pdcd1)
MPAH: 110322459(Pdcd1)
RNO: 301626(Pdcd1)
MUN: 110545716(Pdcd1)
CGE: 100774461(Pdcd1)
NGI: 103730858(Pdcd1)
HGL: 101725530(Pdcd1)
CCAN: 109682463(Pdcd1)
OCU: 100343779(PDCD1)
TUP: 102494356(PDCD1)
CFA: 486213(PDCD1)
VVP: 112911230(PDCD1)
AML: 100476574(PDCD1)
UMR: 103662595(PDCD1)
UAH: 113249252(PDCD1)
ORO: 101369267(PDCD1)
FCA: 100135770(PDCD1)
AJU: 106984598(PDCD1)
BTA: 613842(PDCD1)
BOM: 102275914(PDCD1)
BIU: 109556613(PDCD1)
BBUB: 102397066(PDCD1)
PHD: 102323987(PDCD1)
CHX: 102168321(PDCD1)
OAS: 101121636(PDCD1)
SSC: 100533201(PDCD1)
CFR: 102518269(PDCD1)
CDK: 105096198(PDCD1)
BACU: 103015676(PDCD1)
LVE: 103073818
OOR: 101284451(PDCD1)
DLE: 111172021(PDCD1)
ECB: 100067948(PDCD1)
EPZ: 103560349(PDCD1)
EAI: 106844916(PDCD1)
MYB: 102260940(PDCD1)
MYD: 102769009(PDCD1)
MNA: 107530026(PDCD1)
HAI: 109373809(PDCD1)
RSS: 109439202(PDCD1)
DRO: 112308039(PDCD1)
PALE: 102879076(PDCD1)
TMU: 101342879
MDO: 100012303(PDCD1)
SHR: 105750068(PDCD1)
PCW: 110210180(PDCD1)
OAA: 103170656(PDCD1)
GGA: 424913(PDCD1)
MGP: 104912661(PDCD1)
CJO: 107318303(PDCD1)
APLA: 101804403(PDCD1)
ACYG: 106044776(PDCD1)
TGU: 105759517(PDCD1)
SCAN: 103815621(PDCD1)
FAB: 101816708(PDCD1)
PMAJ: 107208621(PDCD1)
CCAE: 111933442(PDCD1)
CCW: 104688123(PDCD1)
ETL: 114057593(PDCD1)
FPG: 101914756(PDCD1)
FCH: 102058740(PDCD1)
CLV: 102092925(PDCD1)
EGZ: 104123399(PDCD1)
NNI: 104015724(PDCD1)
ACUN: 113483607(PDCD1)
AAM: 106498015(PDCD1)
ASN: 102385757(PDCD1)
AMJ: 106737595(PDCD1)
PSS: 102445197
CMY: 102939118
CPIC: 101943275(PDCD1)
ACS: 103281312(pdcd1)
PVT: 110070319(PDCD1)
XTR: 101730727(pdcd1)
NPR: 108791176(PDCD1)
SGH: 107551375
CCAR: 109073911
IPU: 108268760
HCQ: 109518949
CMK: 103182617
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7851902
  Authors
Shinohara T, Taniwaki M, Ishida Y, Kawaichi M, Honjo T
  Title
Structure and chromosomal localization of the human PD-1 gene (PDCD1).
  Journal
Genomics 23:704-6 (1994)
DOI:10.1006/geno.1994.1562
  Sequence
[hsa:5133]
Reference
  Authors
Keir ME, Butte MJ, Freeman GJ, Sharpe AH
  Title
PD-1 and its ligands in tolerance and immunity.
  Journal
Annu Rev Immunol 26:677-704 (2008)
DOI:10.1146/annurev.immunol.26.021607.090331
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