KEGG ORTHOLOGY: K06839

ORTHOLOGY: K06839

Entry

K06839                      KO

Symbol

SLIT2

Name

slit 2

Pathway

map04360

Axon guidance

map04361

Axon regeneration

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K06839  SLIT2; slit 2
   04361 Axon regeneration
    K06839  SLIT2; slit 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K06839  SLIT2; slit 2
Glycosaminoglycan binding proteins [BR:ko00536]
Heparan sulfate / Heparin
  Axon guidance molecules
   K06839  SLIT2; slit 2

Genes

HSA:	9353(SLIT2)

PTR:	461137(SLIT2)

PPS:	100983369(SLIT2)

GGO:	101128679(SLIT2)

PON:	100434105(SLIT2)

NLE:	100584788(SLIT2)

MCC:	715470(SLIT2)

MCF:	101866138(SLIT2)

MTHB:

126954989

CSAB:

103246295(SLIT2)

CATY:

105579008(SLIT2)

PANU:

101000253(SLIT2)

TGE:	112624821(SLIT2)

RRO:	104673234(SLIT2)

RBB:	108526173(SLIT2)

TFN:	117085198(SLIT2)

PTEH:

111539187(SLIT2)

CJC:	100413159(SLIT2)

SBQ:	101042367(SLIT2)

CSYR:

103256503(SLIT2)

MMUR:

105856059(SLIT2)

LCAT:

123637329

OGA:	100946215(SLIT2)

MMU:	20563(Slit2)

MCAL:

110293912(Slit2)

MPAH:

110330526(Slit2)

RNO:	360272(Slit2)

MCOC:

116070780(Slit2)

MUN:	110539991(Slit2)

CGE:

100752994

MAUA:

101823006(Slit2)

PLEU:

114690889(Slit2)

MORG:

121442275(Slit2)

MFOT:

126506492

AAMP:

119815951(Slit2)

NGI:	103731004(Slit2)

HGL:	101707937(Slit2)

CPOC:

100728211(Slit2)

CCAN:

109676411(Slit2)

DORD:

105980308(Slit2)

DSP:	122104076(Slit2)

NCAR:

124994495

OCU:	100348211(SLIT2)

OPI:	101530170(SLIT2)

TUP:	102478818(SLIT2)

GVR:	103592882(SLIT2)

CFA:	595148(SLIT2)

CLUD:

112653380(SLIT2)

VVP:	112918621(SLIT2)

VLG:	121488892(SLIT2)

AML:	100471504(SLIT2)

UMR:	103658368(SLIT2)

UAH:	113266740(SLIT2)

UAR:	123775870(SLIT2)

ELK:

111148955

LLV:

125093582

MPUF:

101693599(SLIT2)

ORO:	101369792(SLIT2)

EJU:	114197475(SLIT2)

ZCA:	113925116(SLIT2)

MLX:	118010668(SLIT2)

NSU:	110571298(SLIT2)

LWW:	102731368(SLIT2)

FCA:	101084791(SLIT2)

PYU:	121037665(SLIT2)

PBG:	122467232(SLIT2)

LRUF:

124520495

PTG:	102950042(SLIT2)

PPAD:

109269607(SLIT2)

AJU:	106986833(SLIT2)

HHV:	120219738(SLIT2)

BTA:	534164(SLIT2)

BOM:	102272753(SLIT2)

BIU:	109560361(SLIT2)

BBUB:

102395026(SLIT2)

BBIS:

105003192(SLIT2)

CHX:	102191126(SLIT2)

OAS:	100125611(SLIT2)

ODA:	120861971(SLIT2)

CCAD:

122422394(SLIT2)

SSC:	100620577(SLIT2)

CFR:	102516198(SLIT2)

CBAI:

105075308(SLIT2)

CDK:	105098377(SLIT2)

VPC:	102534674(SLIT2)

BACU:

102998012(SLIT2)

LVE:	103085005(SLIT2)

OOR:	101289133(SLIT2)

DLE:	111171163(SLIT2)

PCAD:

102981311(SLIT2)

PSIU:

116754550(SLIT2)

ECB:	100068338(SLIT2)

EPZ:	103553517(SLIT2)

EAI:	106829627(SLIT2)

MYB:	102257391(SLIT2)

MYD:	102772066(SLIT2)

MMYO:

118667178(SLIT2)

MLF:	102427547(SLIT2)

MNA:	107527109(SLIT2)

PKL:	118708343(SLIT2)

HAI:	109389032(SLIT2)

DRO:	112316743(SLIT2)

SHON:

118986285(SLIT2)

AJM:	119045899(SLIT2)

PDIC:

114492837(SLIT2)

PHAS:

123815708(SLIT2)

MMF:	118637817(SLIT2)

RFQ:	117022310(SLIT2)

PALE:

102888760(SLIT2)

PGIG:

120582791(SLIT2)

PVP:	105295998(SLIT2)

RAY:	107498293(SLIT2)

MJV:	108410070(SLIT2)

TOD:	119261203(SLIT2)

SARA:

101555316(SLIT2)

LAV:	100663413(SLIT2)

TMU:

101343863

ETF:	101653981(SLIT2)

DNM:	101441945(SLIT2)

MDO:	100014153(SLIT2)

GAS:	123252016(SLIT2)

SHR:	100933171(SLIT2)

PCW:	110212609(SLIT2)

OAA:	100082591(SLIT2)

GGA:	373967(SLIT2)

PCOC:

116225970(SLIT2)

MGP:	100543362(SLIT2)

CJO:	107313976(SLIT2)

NMEL:

110398403(SLIT2)

APLA:

101800168(SLIT2)

ACYG:

106033442

AFUL:

116489107(SLIT2)

TGU:	100223770(SLIT2)

LSR:	110484047(SLIT2)

SCAN:

103824456(SLIT2)

PMOA:

120497479(SLIT2)

OTC:	121334975(SLIT2)

PRUF:

121356725(SLIT2)

GFR:	102034605(SLIT2)

FAB:	101810047(SLIT2)

PHI:	102114033(SLIT2)

PMAJ:

107203426(SLIT2)

CCAE:

111928155(SLIT2)

CCW:	104690896(SLIT2)

CBRC:

103625667(SLIT2)

ETL:	114066955(SLIT2)

ZAB:	102073291(SLIT2)

ACHL:

103806478(SLIT2)

FPG:	101913898(SLIT2)

FCH:	102047951(SLIT2)

CLV:	102086466(SLIT2)

EGZ:	104134463(SLIT2)

NNI:	104017623(SLIT2)

PLET:

104614169(SLIT2)

PCRI:

104035507(SLIT2)

ACUN:

113479048(SLIT2)

TALA:

104359782(SLIT2)

PADL:

103917016(SLIT2)

AFOR:

103898782(SLIT2)

ACHC:

115341257(SLIT2)

HLE:	104837609(SLIT2)

AGEN:

126035909

GCL:

127015464

CCRI:

104168733(SLIT2)

EHS:	104511331(SLIT2)

MUI:	104546101(SLIT2)

GSTE:

104262389(SLIT2)

LDI:

104351500

MNB:	103779530(SLIT2)

OHA:	104329247(SLIT2)

NNT:	104400072(SLIT2)

DPUB:

104309175(SLIT2)

PGUU:

104467555(SLIT2)

ACAR:

104527063

CPEA:

104391902(SLIT2)

AVIT:

104278427(SLIT2)

CVF:	104288795(SLIT2)

CUCA:

104067464(SLIT2)

TEO:	104378765(SLIT2)

BRHI:

104498884(SLIT2)

AAM:	106498705(SLIT2)

AROW:

112969569(SLIT2)

NPD:	112958520(SLIT2)

TGT:	104569364(SLIT2)

DNE:	112996478(SLIT2)

SCAM:

104143113(SLIT2)

ASN:	102370081(SLIT2)

AMJ:	102563006(SLIT2)

CPOO:

109322043(SLIT2)

GGN:	109303790(SLIT2)

PSS:	102462186(SLIT2)

CMY:	102947569(SLIT2)

CPIC:

101951540(SLIT2)

TST:	117877761(SLIT2)

CABI:

116817614(SLIT2)

MRV:	120406502(SLIT2)

ACS:	100558087(slit2)

PVT:	110072268(SLIT2)

SUND:

121931173(SLIT2)

PBI:	103052201(SLIT2)

PMUR:

107296070(SLIT2)

CTIG:

120304868(SLIT2)

PGUT:

117676496(SLIT2)

VKO:	123016924(SLIT2)

PMUA:

114604556

ZVI:	118083661(SLIT2)

GJA:	107122953(SLIT2)

STOW:

125439593(SLIT2)

XLA:	108698051 394404(slit2.S)

XTR:	100492007(slit2)

NPR:	108791311(SLIT2)

RTEM:

120924317(SLIT2)

BBUF:

120990311(SLIT2)

BGAR:

122938598(SLIT2)

DRE:	80353(slit2)

SRX:	107745853(slit2) 107757564

SANH:

107695646 107700301

SGH:	107598298 107600654(slit2)

CCAR:

109054879 109081075

CAUA:

113044130 113108429

PPRM:

120494496(slit2)

MAMB:

125272675(slit2)

IPU:	108260585(slit2)

PHYP:

113544359(slit2)

SMEO:

124381263(slit2)

AMEX:

103027846

EEE:	113586902(slit2)

TRU:	101068313(slit2)

TNG:	GSTEN00009178G001

LCO:	104923169(slit2)

NCC:

104967810

CGOB:

115008228(slit2)

ELY:	117255238(slit2)

EFO:	125886437(slit2)

PLEP:

121941922(slit2)

SLUC:

116040415(slit2)

ECRA:

117935557(slit2)

ESP:	116700511(slit2)

PFLV:

114564361(slit2)

GAT:	120825593(slit2)

PPUG:

119217790(slit2)

MSAM:

119899060(slit2)

CUD:	121508719(slit2)

ALAT:

119012767(slit2)

MZE:	101467229(slit2)

ONL:	100694794(slit2)

OAU:	116329083(slit2)

OLA:	101173607(slit2)

OML:	112157251(slit2)

XMA:	102220623(slit2)

XCO:	114144726(slit2)

XHE:	116719991(slit2)

PRET:

103466945(slit2)

PFOR:

103137906(slit2)

PLAI:

106947374(slit2)

PMEI:

106914213(slit2)

GAF:	122830173(slit2)

CVG:	107093490(slit2)

CTUL:

119788448(slit2)

GMU:	124868241(slit2)

NFU:	107382134(slit2)

KMR:	108230788(slit2)

ALIM:

106520917(slit2)

NWH:	119407513(slit2)

AOCE:

111568163(slit2)

MCEP:

125004109(slit2)

CSEM:

103383686(slit2)

POV:	109637842(slit2)

SSEN:

122770997(slit2)

HHIP:

117760180(slit2)

HSP:	118120096(slit2)

LCF:

108896582

SDU:	111231408(slit2)

SLAL:

111664028(slit2)

XGL:	120800409(slit2)

HCQ:	109519858(slit2)

BPEC:

110165294(slit2)

MALB:

109961362(slit2)

BSPL:

114843628(slit2)

SASA:

106591151

OTW:	112262345(slit2)

OMY:	110516422(slit2)

OGO:

124024905

CCLU:

121562013(slit2) 121565232

ELS:	105009147(slit2)

SFM:	108924359(slit2)

PKI:	111837340(slit2)

AANG:

118227911(slit2)

LOC:	102694474(slit2)

PSPA:

121324378 121329799

ARUT:

117409251 117421182

PSEX:

120527765(slit2)

LCM:	102367424(SLIT2)

CMK:	103175815(slit2)

RTP:	109920161(slit2)

BFO:	118406803 118414987

BBEL:

109467364 109467412 109467413 109474439 109478478

CIN:

SCLV:

APLC:

AJC:

SKO:

DME:	Dmel_CG43758(sli)

DER:

6548871

DSE:

6609339

DSI:	Dsimw501_GD25590(Dsim_GD25590)

DYA:	Dyak_GE14122

DAN:

DSR:

DPO:

DPE:

DMN:	108159366 117193781

DWI:

6639686

DGR:

6559138

DMO:	Dmoj_GI21301

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

RZE:	108360647 108378117

MDE:

SCAC:

LCQ:

LSQ:

HIS:

AGA:	AgaP_AGAP002793

ACOZ:

AARA:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ004328

CPII:

120421017

CNS:

116348173

BCOO:

119071133

AME:	408960 727408

ACER:

107995313

ALAB:

122718568

BIM:	100745615 100748420

BBIF:

117214354 117216001

BVK:	117237625 117242351

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:	105265548 105267193

DAM:

AGIF:

CINS:

LHT:

CCIN:

TCA:	660980(sli)

DPA:	109546161 125502386 125504099

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

NIQ:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

CFEL:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM419730

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

FCD:

DPX:	DAPPUDRAFT_304927

DMK:

116916920

DPZ:

124335774

PVM:	113800972 113811035

PJA:	122251403 122255042

PCHN:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:

CSCU:

PTEP:

SDM:

CEL:	CELE_F40E10.4(slt-1)

CBR:	CBG_07570(Cbr-slt-1)

BMY:	BM_BM3960(Bma-slt-1)

LOA:	LOAG_01152

HRO:	HELRODRAFT_103882

LGI:	LOTGIDRAFT_232797

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:

EGL:

TAD:	TRIADDRAFT_58750

» show all

Reference

PMID:9813312

Authors

Itoh A, Miyabayashi T, Ohno M, Sakano S

Title

Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

Journal

Brain Res Mol Brain Res 62:175-86 (1998)
DOI:10.1016/S0169-328X(98)00224-1

Sequence

[hsa:9353]

Reference

PMID:18363568

Authors

Hohenester E

Title

Structural insight into Slit-Robo signalling.

Journal

Biochem Soc Trans 36:251-6 (2008)
DOI:10.1042/BST0360251

LinkDB

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