KEGG   ORTHOLOGY: K07376Help
Entry
K07376                      KO                                     

Name
PRKG1
Definition
cGMP-dependent protein kinase 1 [EC:2.7.11.12]
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04540  Gap junction
ko04611  Platelet activation
ko04713  Circadian entrainment
ko04714  Thermogenesis
ko04730  Long-term depression
ko04740  Olfactory transduction
ko04923  Regulation of lipolysis in adipocytes
ko04970  Salivary secretion
Disease
H00801  Familial thoracic aortic aneurysm and dissection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09154 Digestive system
   04970 Salivary secretion
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09156 Nervous system
   04730 Long-term depression
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09157 Sensory system
   04740 Olfactory transduction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K07376  PRKG1; cGMP-dependent protein kinase 1
   04714 Thermogenesis
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07376  PRKG1; cGMP-dependent protein kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.12  cGMP-dependent protein kinase
     K07376  PRKG1; cGMP-dependent protein kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKG family
   K07376  PRKG1; cGMP-dependent protein kinase 1
BRITE hierarchy
Other DBs
GO: 0004692
Genes
HSA: 5592(PRKG1)
PTR: 744467(PRKG1)
PPS: 100975252(PRKG1)
GGO: 101148943(PRKG1)
PON: 100437791(PRKG1)
NLE: 100597697(PRKG1)
MCC: 703356(PRKG1)
MCF: 102122483(PRKG1)
CSAB: 103216192(PRKG1)
RRO: 104676729(PRKG1)
CJC: 100388016(PRKG1)
SBQ: 101043597(PRKG1)
MMU: 19091(Prkg1)
MCAL: 110285294(Prkg1)
MPAH: 110313055(Prkg1)
RNO: 54286(Prkg1)
CGE: 100768615(Prkg1)
NGI: 103732508(Prkg1)
HGL: 101708361(Prkg1)
CCAN: 109680559 109700389(Prkg1)
OCU: 100008694(PRKG1)
CFA: 609616(PRKG1)
VVP: 112931969(PRKG1)
AML: 100481505
UMR: 103661993(PRKG1)
UAH: 113258870(PRKG1)
FCA: 101097420(PRKG1)
PTG: 102969150(PRKG1)
PPAD: 109255410(PRKG1)
AJU: 106969513(PRKG1)
BTA: 282004(PRKG1)
BOM: 102279305(PRKG1)
BIU: 109579117(PRKG1)
BBUB: 102407722(PRKG1)
CHX: 102182753(PRKG1)
OAS: 443010(PRKG1)
SSC: 733640(PRKG1)
CFR: 102509252(PRKG1)
CDK: 105085256(PRKG1)
BACU: 103012801(PRKG1)
LVE: 103071917(PRKG1)
OOR: 101279276(PRKG1)
DLE: 111172539(PRKG1)
PCAD: 102991499(PRKG1)
ECB: 100071872(PRKG1)
EPZ: 103556704 103563033(PRKG1)
EAI: 106847454(PRKG1)
MYB: 102255009(PRKG1)
MNA: 107543282(PRKG1)
HAI: 109387521(PRKG1)
DRO: 112307314(PRKG1)
PALE: 102884723(PRKG1)
RAY: 107515478(PRKG1)
MJV: 108384319 108396675(PRKG1)
LAV: 100662471(PRKG1)
MDO: 100023016(PRKG1)
SHR: 100928746(PRKG1)
PCW: 110199927(PRKG1)
OAA: 100073431(PRKG1)
GGA: 423682(PRKG1)
MGP: 100540173(PRKG1)
CJO: 107315639(PRKG1)
NMEL: 110390491(PRKG1)
APLA: 101802614(PRKG1)
ACYG: 106030263(PRKG1)
TGU: 100229896(PRKG1)
LSR: 110474019(PRKG1)
SCAN: 103823826(PRKG1)
GFR: 102041315(PRKG1)
FAB: 101816835(PRKG1)
PHI: 102105641(PRKG1)
PMAJ: 107207071(PRKG1)
CCW: 104695105(PRKG1)
ETL: 114065114(PRKG1)
FPG: 101914750(PRKG1)
FCH: 102051167(PRKG1)
CLV: 102098659(PRKG1)
EGZ: 104125151(PRKG1)
NNI: 104013515(PRKG1)
ACUN: 113481922(PRKG1)
PADL: 103924272(PRKG1) 103924282
AAM: 106486427(PRKG1)
ASN: 102385836(PRKG1)
AMJ: 102573015(PRKG1)
PSS: 102462425(PRKG1) 102463494
CMY: 102942713(PRKG1)
CPIC: 101953224(PRKG1)
ACS: 100563289
PBI: 103062615(PRKG1)
PMUR: 107291096 107294548(PRKG1)
TSR: 106545399 106546019(PRKG1)
PMUA: 114597269(PRKG1)
GJA: 107113865(PRKG1)
XLA: 108696071 108697357(prkg1.S)
XTR: 100494278(prkg1)
NPR: 108797031(PRKG1)
DRE: 394005(prkg1a)
IPU: 108263833(PRKG1) 108265376 108274270(prkg1)
PKI: 111838490 111853690(prkg1)
CMK: 103180883(prkg1) 103190998
CIN: 100184124
SPU: 585077
DME: Dmel_CG10033(for) Dmel_CG3324(Pkg21D) Dmel_CG4839(CG4839)
DSI: Dsimw501_GD22740(Dsim_GD22740) Dsimw501_GD22942(Dsim_GD22942) Dsimw501_GD23660(Dsim_GD23660)
AME: 406092(For) 551714
NVI: 100114234 100117965(NV50043) 100119839(for)
CSOL: 105361340
BMOR: 101735910 692605(PKG-I)
CEL: CELE_F55A8.2(egl-4)
CBR: CBG08401(Cbr-egl-4)
BMY: Bm1_37920
TSP: Tsp_02535
HMG: 100199173 100201371(prkg1)
AQU: 100636239
PPP: 112291101
CRE: CHLREDRAFT_181974(CGK2)
MNG: MNEG_5029
PYO: PY17X_1009800(PY02304)
PCB: PCHAS_100910(PC000298.03.0)
TAN: TA04955
TPV: TP03_0511
BBO: BBOV_I004690(19.m02237)
CPV: cgd8_750
TGO: TGME49_311360(PKG)
SMIN: v1.2.000817.t1(symbB.v1.2.000817.t1) v1.2.000877.t1(symbB.v1.2.000877.t1) v1.2.003252.t1(symbB.v1.2.003252.t1) v1.2.004287.t1(symbB.v1.2.004287.t1) v1.2.006098.t1(symbB.v1.2.006098.t1) v1.2.008273.t1(symbB.v1.2.008273.t1) v1.2.008273.t2(symbB.v1.2.008273.t2) v1.2.009118.t1(symbB.v1.2.009118.t1) v1.2.009164.t1(symbB.v1.2.009164.t1) v1.2.010262.t1(symbB.v1.2.010262.t1) v1.2.010262.t2(symbB.v1.2.010262.t2) v1.2.011180.t1(symbB.v1.2.011180.t1) v1.2.012476.t1(symbB.v1.2.012476.t1) v1.2.012476.t2(symbB.v1.2.012476.t2) v1.2.015884.t1(symbB.v1.2.015884.t1) v1.2.016972.t2(symbB.v1.2.016972.t2) v1.2.017815.t1(symbB.v1.2.017815.t1) v1.2.018584.t1(symbB.v1.2.018584.t1) v1.2.022723.t1(symbB.v1.2.022723.t1) v1.2.023087.t1(symbB.v1.2.023087.t1) v1.2.023463.t1(symbB.v1.2.023463.t1) v1.2.023465.t1(symbB.v1.2.023465.t1) v1.2.023864.t1(symbB.v1.2.023864.t1) v1.2.027542.t1(symbB.v1.2.027542.t1) v1.2.031517.t1(symbB.v1.2.031517.t1) v1.2.031929.t1(symbB.v1.2.031929.t1) v1.2.033790.t1(symbB.v1.2.033790.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sausbier M, Schubert R, Voigt V, Hirneiss C, Pfeifer A, Korth M, Kleppisch T, Ruth P, Hofmann F
  Title
Mechanisms of NO/cGMP-dependent vasorelaxation.
  Journal
Circ Res 87:825-30 (2000)
DOI:10.1161/01.RES.87.9.825
  Sequence
[mmu:19091]
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