KEGG   ORTHOLOGY: K07831Help
Entry
K07831                      KO                                     

Name
MRAS
Definition
Ras-related protein M-Ras
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04137  Mitophagy - animal
ko04140  Autophagy - animal
ko04218  Cellular senescence
ko04371  Apelin signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
   04015 Rap1 signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
   04010 MAPK signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
   04371 Apelin signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
   04072 Phospholipase D signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K07831  MRAS; Ras-related protein M-Ras
   04137 Mitophagy - animal
    K07831  MRAS; Ras-related protein M-Ras
  09143 Cell growth and death
   04218 Cellular senescence
    K07831  MRAS; Ras-related protein M-Ras
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K07831  MRAS; Ras-related protein M-Ras
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K07831  MRAS; Ras-related protein M-Ras
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K07831  MRAS; Ras-related protein M-Ras
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07831  MRAS; Ras-related protein M-Ras
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    K07831  MRAS; Ras-related protein M-Ras
BRITE hierarchy
Genes
HSA: 22808(MRAS)
PTR: 470938(MRAS)
PPS: 100973448(MRAS)
GGO: 101146138(MRAS)
PON: 100431849(MRAS)
NLE: 100581488(MRAS)
MCC: 716352(MRAS)
MCF: 101865297(MRAS)
CSAB: 103241604(MRAS)
RRO: 104662303(MRAS)
RBB: 108544611(MRAS)
CJC: 100390332(MRAS)
SBQ: 101053335(MRAS)
MMU: 17532(Mras)
MCAL: 110300983(Mras)
MPAH: 110327401(Mras)
RNO: 25482(Mras)
MUN: 110548400(Mras)
CGE: 100767950(Mras)
NGI: 103737601(Mras)
HGL: 101709042(Mras)
CCAN: 109693559(Mras)
OCU: 100358182(MRAS)
TUP: 102468234(MRAS)
CFA: 477082(MRAS)
VVP: 112935006(MRAS)
AML: 100470119(MRAS)
UMR: 103678665(MRAS)
UAH: 113253984(MRAS)
ORO: 101362579(MRAS)
FCA: 101092784(MRAS)
PTG: 102970438(MRAS)
PPAD: 109259803(MRAS)
AJU: 106976712(MRAS)
BTA: 540803(MRAS)
BOM: 102276240(MRAS)
BIU: 109559860(MRAS)
BBUB: 102391353(MRAS)
CHX: 102185873(MRAS)
OAS: 101110290(MRAS)
SSC: 100621398(MRAS)
CFR: 102518807(MRAS)
CDK: 105086302(MRAS)
BACU: 103016009(MRAS)
LVE: 103087313(MRAS)
OOR: 101281431(MRAS)
DLE: 111179228(MRAS)
PCAD: 102974392(MRAS)
ECB: 100064781(MRAS)
EPZ: 103550584(MRAS)
EAI: 106838095(MRAS)
MYB: 102261560(MRAS)
MYD: 102757500(MRAS)
MNA: 107532623(MRAS)
HAI: 109394119(MRAS)
DRO: 112309967(MRAS)
PALE: 102879891(MRAS)
RAY: 107513955(MRAS)
MJV: 108406677(MRAS)
LAV: 100661766(MRAS)
TMU: 101357647
MDO: 100017121(MRAS)
SHR: 100926472(MRAS)
PCW: 110208214(MRAS)
OAA: 103169212(MRAS)
GGA: 395149(MRAS)
MGP: 100544446(MRAS)
CJO: 107316847(MRAS)
NMEL: 110399841(MRAS)
APLA: 101802364(MRAS)
ACYG: 106034261(MRAS)
TGU: 100225544(MRAS)
LSR: 110468317(MRAS)
SCAN: 103814330(MRAS)
GFR: 102033145(MRAS)
FAB: 101818393(MRAS)
PHI: 102111139(MRAS)
PMAJ: 107207566(MRAS)
CCAE: 111932216(MRAS)
CCW: 104693996(MRAS)
ETL: 114055508(MRAS)
FPG: 101919448(MRAS)
FCH: 102047148(MRAS)
CLV: 102088763(MRAS)
EGZ: 104131516(MRAS)
NNI: 104018970(MRAS)
ACUN: 113482327(MRAS)
PADL: 103919617(MRAS)
AAM: 106499141(MRAS)
ASN: 102376534(MRAS)
AMJ: 102573274(MRAS)
PSS: 102449741(MRAS)
CMY: 102944213
CPIC: 101938587(MRAS)
ACS: 100564299(mras)
PVT: 110085358(MRAS)
PBI: 103048700(MRAS)
PMUR: 107295186(MRAS)
TSR: 106539618(MRAS)
PMUA: 114603604(MRAS)
GJA: 107122828(MRAS)
XTR: 100496446(mras)
NPR: 108797141(MRAS)
DRE: 100317924(mras) 100536317(si:ch73-116o1.2)
IPU: 100528485(rasm) 108266255(MRAS)
EEE: 113581478 113592099(mras)
TRU: 101069411(mras)
LCO: 104929243(mras)
NCC: 104957687(mras)
MZE: 101469336(mras)
ONL: 100690274(mras)
OLA: 101159234(mras)
XMA: 102230541(mras)
XCO: 114148358(mras)
PRET: 103460380(mras)
CVG: 107100172(mras)
NFU: 107390181(mras)
KMR: 108238565(mras)
ALIM: 106526991(mras)
AOCE: 111579771(mras)
CSEM: 103392459(mras)
POV: 109642367(mras)
LCF: 108887106(mras)
SDU: 111218153(mras)
SLAL: 111667451(mras)
HCQ: 109523396(mras)
BPEC: 110164049(mras)
MALB: 109968557(mras)
PKI: 111849456 111851762(mras)
LCM: 102356108 102359118(MRAS)
CMK: 103180429(mras)
RTP: 109932084(mras)
CIN: 100181151
SPU: 579665
APLC: 110973416
SKO: 100370842
AME: 410415
BIM: 100748982
BTER: 100649070
CCAL: 108633060
OBB: 114877070
SOC: 105196594
MPHA: 105835603
AEC: 105145724
ACEP: 105624153
PBAR: 105430141
VEM: 105565162
HST: 105181630
DQU: 106742364
CFO: 105257128
LHU: 105678189
PGC: 109859072
OBO: 105278374
PCF: 106786815
NVI: 100117915
CSOL: 105364580
MDL: 103576496
TCA: 660624
DPA: 109535138
NVL: 108561718
BMOR: 101741618
PMAC: 106710401
PRAP: 110997177
HAW: 110380887
TNL: 113501979
PXY: 105394695
API: 100160392
DNX: 107166538
AGS: 114120874
RMD: 113548563
BTAB: 109034061
CLEC: 106662627
ZNE: 110837997
FCD: 110846429
PVM: 113800348
PTEP: 107443955
CEL: CELE_F17C8.4(ras-2)
CBR: CBG17997(Cbr-ras-2)
BMY: Bm1_10760
PCAN: 112563621
CRG: 105325397
MYI: 110460098
OBI: 106871291
SHX: MS3_06347
EGL: EGR_02047
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F
  Title
A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.
  Journal
Mol Cell 22:217-30 (2006)
DOI:10.1016/j.molcel.2006.03.027
Reference
PMID:9400994
  Authors
Kimmelman A, Tolkacheva T, Lorenzi MV, Osada M, Chan AM
  Title
Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution.
  Journal
Oncogene 15:2675-85 (1997)
DOI:10.1038/sj.onc.1201674
  Sequence
[hsa:22808]
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