KEGG   ORTHOLOGY: K07861Help
Entry
K07861                      KO                                     

Name
RAC3
Definition
Ras-related C3 botulinum toxin substrate 3
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04071  Sphingolipid signaling pathway
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04370  VEGF signaling pathway
ko04510  Focal adhesion
ko04520  Adherens junction
ko04650  Natural killer cell mediated cytotoxicity
ko04662  B cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05135  Yersinia infection
ko05163  Human cytomegalovirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05231  Choline metabolism in cancer
ko05416  Viral myocarditis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04015 Rap1 signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04010 MAPK signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04310 Wnt signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04370 VEGF signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04071 Sphingolipid signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04024 cAMP signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04520 Adherens junction
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04662 B cell receptor signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04664 Fc epsilon RI signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   04062 Chemokine signaling pathway
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09158 Development and regeneration
   04360 Axon guidance
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   05231 Choline metabolism in cancer
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09162 Cancer: specific types
   05210 Colorectal cancer
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   05212 Pancreatic cancer
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   05416 Viral myocarditis
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
   05163 Human cytomegalovirus infection
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
BRITE hierarchy
Genes
HSA: 5881(RAC3)
PTR: 747131(RAC3)
PPS: 100988790(RAC3)
PON: 112129584(RAC3)
NLE: 100602123(RAC3)
MCC: 719305(RAC3)
MCF: 102143597(RAC3)
CSAB: 103243748(RAC3)
RRO: 104654979(RAC3)
RBB: 108534092(RAC3)
CJC: 100400756(RAC3)
SBQ: 101046124(RAC3)
MMU: 170758(Rac3)
MCAL: 110305163(Rac3)
MPAH: 110331528(Rac3)
MUN: 110548820(Rac3)
CGE: 100757479(Rac3)
NGI: 103730658(Rac3)
HGL: 101723777(Rac3)
CCAN: 109702872(Rac3)
TUP: 102494727(RAC3)
VVP: 112920582(RAC3)
AML: 100468971(RAC3)
UMR: 103666008(RAC3)
UAH: 113244670(RAC3)
ORO: 101374128(RAC3)
FCA: 101080496(RAC3)
PTG: 102955504(RAC3)
PPAD: 109277132(RAC3)
AJU: 106986311(RAC3)
BTA: 619066(RAC3)
BOM: 102286986(RAC3)
BIU: 109574290(RAC3)
BBUB: 102413174(RAC3)
CHX: 102178569(RAC3)
OAS: 101112406(RAC3)
SSC: 110255928(RAC3)
CFR: 102508710(RAC3)
CDK: 105102215(RAC3)
BACU: 103019253(RAC3)
LVE: 103079514(RAC3)
OOR: 101278177(RAC3)
DLE: 111182681(RAC3)
PCAD: 102992553(RAC3)
ECB: 100054738(RAC3)
EPZ: 103551104(RAC3)
EAI: 106846070(RAC3)
MYB: 102249503(RAC3)
MYD: 102760578(RAC3)
MNA: 107539040(RAC3)
HAI: 109393041(RAC3)
DRO: 112298813(RAC3)
PALE: 102887421(RAC3)
RAY: 107520254(RAC3)
MJV: 108395251(RAC3)
TMU: 101360313
MDO: 100029873(RAC3)
SHR: 100924669(RAC3)
PCW: 110218260(RAC3)
OAA: 114808823(RAC3)
GGA: 395870(RAC3)
MGP: 100544672(RAC3)
CJO: 107322082(RAC3)
NMEL: 110407289(RAC3)
APLA: 101794915(RAC3)
ACYG: 106046763(RAC3)
TGU: 100220185(RAC3)
LSR: 110472410(RAC3)
SCAN: 103819726(RAC3)
GFR: 102043334(RAC3)
FAB: 101821880(RAC3)
PHI: 102103513(RAC3)
PMAJ: 107212321(RAC3)
CCAE: 111937502(RAC3)
CCW: 104698185(RAC3)
ETL: 114060329(RAC3)
FPG: 101915014(RAC3)
FCH: 102054322(RAC3)
CLV: 102094546(RAC3)
EGZ: 104131087(RAC3)
NNI: 104014320(RAC3)
ACUN: 113486843(RAC3)
PADL: 103917419(RAC3)
ASN: 102384004(RAC3)
AMJ: 102563759(RAC3)
PSS: 102455375(RAC3)
CMY: 102938636(RAC3)
CPIC: 101934732(RAC3)
ACS: 100568092(rac3)
PVT: 110091292(RAC3)
PBI: 103065986(RAC3)
PMUR: 107288862(RAC3)
PMUA: 114589702(RAC3)
GJA: 107118111(RAC3)
XLA: 108700975
XTR: 100101726(rac3)
NPR: 108791334(RAC3)
DRE: 437027(rac3a) 795167(rac3b)
IPU: 108259609(rac3)
PHYP: 113528174
AMEX: 103047109(rac3) 111192386
EEE: 113574264 113580284(rac3)
TRU: 101064595
NCC: 104965188
MZE: 101467064
ONL: 100712409(rac3)
OLA: 105354522
XMA: 102224880
XCO: 114150885(rac3)
PRET: 103482188
CVG: 107087645
NFU: 107395638
KMR: 108245165
AOCE: 111565174(rac3)
CSEM: 103381664
SDU: 111237036
SLAL: 111664334(rac3)
HCQ: 109529292
BPEC: 110154419
MALB: 109966668
OTW: 112224482(rac3) 112259175
SALP: 112070913 112080422(rac3)
ELS: 105005703(rac3) 105031329
SFM: 108940081(rac3)
PKI: 111848451(rac3) 111856750
LCM: 102364586(RAC3)
CMK: 103175476(rac3)
RTP: 109930936
MPHA: 105840874
ABP: AGABI1DRAFT96759(AGABI1DRAFT_96759)
ABV: AGABI2DRAFT239537(AGABI2DRAFT_239537)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9252344
  Authors
Haataja L, Groffen J, Heisterkamp N
  Title
Characterization of RAC3, a novel member of the Rho family.
  Journal
J Biol Chem 272:20384-8 (1997)
DOI:10.1074/jbc.272.33.20384
  Sequence
[hsa:5881]
Reference
  Authors
Haataja L, Kaartinen V, Groffen J, Heisterkamp N
  Title
The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading.
  Journal
J Biol Chem 277:8321-8 (2002)
DOI:10.1074/jbc.M105363200
  Sequence
[hsa:5881]
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