KEGG   ORTHOLOGY: K07888
Entry
K07888                      KO                                     
Symbol
RAB5B
Name
Ras-related protein Rab-5B
Pathway
map04014  Ras signaling pathway
map04144  Endocytosis
map04145  Phagosome
map04962  Vasopressin-regulated water reabsorption
map05132  Salmonella infection
map05146  Amoebiasis
map05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07888  RAB5B; Ras-related protein Rab-5B
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K07888  RAB5B; Ras-related protein Rab-5B
   04145 Phagosome
    K07888  RAB5B; Ras-related protein Rab-5B
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K07888  RAB5B; Ras-related protein Rab-5B
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K07888  RAB5B; Ras-related protein Rab-5B
   05152 Tuberculosis
    K07888  RAB5B; Ras-related protein Rab-5B
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K07888  RAB5B; Ras-related protein Rab-5B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07888  RAB5B; Ras-related protein Rab-5B
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07888  RAB5B; Ras-related protein Rab-5B
   04031 GTP-binding proteins
    K07888  RAB5B; Ras-related protein Rab-5B
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab GTPases
    K07888  RAB5B; Ras-related protein Rab-5B
 Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Rab GTPases
    K07888  RAB5B; Ras-related protein Rab-5B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07888  RAB5B; Ras-related protein Rab-5B
  Exosomal proteins of other body fluids (saliva and urine)
   K07888  RAB5B; Ras-related protein Rab-5B
  Exosomal proteins of colorectal cancer cells
   K07888  RAB5B; Ras-related protein Rab-5B
  Exosomal proteins of melanoma cells
   K07888  RAB5B; Ras-related protein Rab-5B
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab5/17/22/31 [OT]
    K07888  RAB5B; Ras-related protein Rab-5B
Genes
HSA: 5869(RAB5B)
PTR: 746457(RAB5B)
PPS: 100983354(RAB5B)
GGO: 101136077(RAB5B)
PON: 100172422(RAB5B)
NLE: 100593361(RAB5B)
MCC: 708347(RAB5B)
MCF: 101865961(RAB5B)
CSAB: 103238494(RAB5B)
CATY: 105578386 105587349(RAB5B)
PANU: 101027064(RAB5B)
TGE: 112634219(RAB5B)
RRO: 104673699(RAB5B)
RBB: 108516054(RAB5B)
TFN: 117089963(RAB5B)
PTEH: 111541869(RAB5B)
CJC: 100408426(RAB5B)
SBQ: 101046115
CSYR: 103266415(RAB5B)
MMUR: 105864957(RAB5B)
LCAT: 123639672(RAB5B)
OGA: 100967196(RAB5B)
MMU: 19344(Rab5b)
MCAL: 110291569 110303170(Rab5b)
MPAH: 110326563(Rab5b)
RNO: 288779(Rab5b)
MCOC: 116076052(Rab5b)
MUN: 110559387(Rab5b)
CGE: 100768837(Rab5b)
MAUA: 101822596(Rab5b)
PLEU: 114681738(Rab5b)
MORG: 121459215(Rab5b)
AAMP: 119803471(Rab5b)
NGI: 103746496(Rab5b)
HGL: 101724150(Rab5b)
CPOC: 100714048(Rab5b)
CCAN: 109698573(Rab5b)
DORD: 105989794(Rab5b)
DSP: 122124350(Rab5b)
OCU: 100348306(RAB5B)
OPI: 101516760(RAB5B)
TUP: 102500692(RAB5B)
CFA: 474394(RAB5B)
VVP: 112922402(RAB5B)
VLG: 121491264(RAB5B)
AML: 100468736(RAB5B)
UMR: 103682516(RAB5B)
UAH: 113256447(RAB5B)
UAR: 123787269(RAB5B)
MPUF: 101674990(RAB5B)
ORO: 101383953(RAB5B)
EJU: 114214936(RAB5B)
ZCA: 113921499(RAB5B)
MLX: 118008733(RAB5B)
FCA: 101093783(RAB5B)
PYU: 121040953(RAB5B)
PBG: 122473737(RAB5B)
PTG: 102960245(RAB5B)
PPAD: 109270310(RAB5B)
AJU: 106986901(RAB5B)
HHV: 120219965(RAB5B)
BTA: 539150(RAB5B)
BOM: 102276679(RAB5B)
BIU: 109559382(RAB5B)
BBUB: 102397928(RAB5B)
CHX: 102174814(RAB5B)
OAS: 101112211(RAB5B)
ODA: 120857425(RAB5B)
CCAD: 122427055(RAB5B) 122431844
SSC: 100625381(RAB5B)
CFR: 102505264(RAB5B)
CBAI: 105075909(RAB5B)
CDK: 105086384(RAB5B)
VPC: 102528941(RAB5B)
BACU: 103013637(RAB5B)
LVE: 103088513(RAB5B)
OOR: 101289329(RAB5B)
DLE: 111173894(RAB5B)
PCAD: 102973277(RAB5B)
PSIU: 116760342(RAB5B)
ECB: 100059099(RAB5B)
EPZ: 103560194(RAB5B)
EAI: 106841298(RAB5B)
MYB: 102257029(RAB5B)
MYD: 102757494(RAB5B)
MMYO: 118652144(RAB5B)
MLF: 102439986(RAB5B)
MNA: 107538222(RAB5B)
PKL: 118728265(RAB5B)
HAI: 109396876(RAB5B)
DRO: 112319058(RAB5B)
SHON: 118975928(RAB5B)
AJM: 119048547(RAB5B)
PDIC: 114506938 114512721(RAB5B)
PHAS: 123812867(RAB5B)
MMF: 118623493(RAB5B)
RFQ: 117028351(RAB5B)
PALE: 102894382(RAB5B)
PGIG: 120604846(RAB5B)
PVP: 105302599(RAB5B)
RAY: 107521267(RAB5B)
MJV: 108389601(RAB5B)
TOD: 119248039(RAB5B)
SARA: 101544573(RAB5B)
LAV: 100668413(RAB5B)
TMU: 101355194
DNM: 101415602(RAB5B) 101447878
MDO: 100017251(RAB5B)
GAS: 123248752(RAB5B)
SHR: 100920142(RAB5B)
PCW: 110210909(RAB5B)
OAA: 114814513(RAB5B)
GGA: 100529061(RAB5B)
PCOC: 116239276(RAB5B)
MGP: 100541892(RAB5B)
CJO: 107325751(RAB5B)
NMEL: 110389217(RAB5B)
APLA: 113840038
AFUL: 116499926(RAB5B)
TGU: 115491460(RAB5B)
LSR: 116184544(RAB5B)
PHI: 102100332(RAB5B)
ETL: 114070801(RAB5B)
FPG: 101910524(RAB5B)
CLV: 102092937(RAB5B)
EGZ: 104135957
NNI: 104017466(RAB5B)
TALA: 116961456(RAB5B)
ACHC: 115350885(RAB5B)
CCRI: 104162557
AAM: 106482107(RAB5B)
AROW: 112961075(RAB5B)
DNE: 112995188(RAB5B)
ASN: 102387725(RAB5B)
AMJ: 102570492(RAB5B)
PSS: 102460366(RAB5B)
CMY: 102944451(RAB5B)
CPIC: 101934577(RAB5B)
CABI: 116827766(RAB5B)
MRV: 120391170(RAB5B)
ACS: 100563281(rab5b)
PVT: 110073523(RAB5B)
SUND: 121921421(RAB5B)
PBI: 103054647(RAB5B)
PMUR: 107287773(RAB5B)
TSR: 106539725(RAB5B)
PGUT: 117662886(RAB5B)
VKO: 123033088(RAB5B)
PMUA: 114587742(RAB5B)
ZVI: 118079610(RAB5B)
GJA: 107105866(RAB5B)
STOW: 125428319(RAB5B)
XLA: 108709835(rab5b.S) 379507(rab5d.S) 414468(rab5b.L)
XTR: 448258(rab5b) 594964(rab5d)
NPR: 108784960 108790530(RAB5B)
RTEM: 120929527(RAB5B) 120943834
BBUF: 120996001(RAB5B) 121008186
BGAR: 122930417(RAB5B) 122945611
DRE: 405821(rab5b)
CCAR: 109065414
PPRM: 120486535(rab5b)
MAMB: 125270258(rab5b)
IPU: 108266395(rab5b)
PHYP: 113547043
SMEO: 124383331(rab5b)
TFD: 113641064(rab5b)
AMEX: 103034209
EEE: 113567539
TRU: 101072093
LCO: 104938166
CGOB: 115026716
ELY: 117251513(rab5b)
PLEP: 121949491(rab5b)
SLUC: 116047637(rab5b)
ECRA: 117953119(rab5b)
PFLV: 114564094
GAT: 120834142(rab5b)
PPUG: 119228567(rab5b)
MSAM: 119904573(rab5b)
CUD: 121522408(rab5b)
ALAT: 119025679(rab5b)
MZE: 101475520
ONL: 100697826
OAU: 116327355(rab5b)
OML: 112137972(rab5b)
XMA: 102224939
XCO: 114147998
XHE: 116722885
PRET: 103481860
GAF: 122839516(rab5b)
CVG: 107102771
CTUL: 119792033(rab5b)
GMU: 124871923(rab5b)
NFU: 107389578
KMR: 108238858(rab5b)
ALIM: 106530758
NWH: 119418932(rab5b)
AOCE: 111563727
MCEP: 125017501(rab5b)
CSEM: 103391561
SSEN: 122762125(rab5b)
HHIP: 117754942 117755305(rab5b)
HSP: 118119590(rab5b)
LCF: 108902502
SDU: 111218236
SLAL: 111659545
XGL: 120801909(rab5b)
HCQ: 109514526
BPEC: 110170657
MALB: 109971649
BSPL: 114847336(rab5b)
SFM: 108918525(rab5b) 108922315
AANG: 118210692 118223726(rab5b)
LOC: 102696857
LCM: 102366232 102367173(RAB5B)
CMK: 103182902(rab5b) 103189563
BBEL: 109465402
SCLV: 120329439
SPU: 578627
TPRE: 106650187
CGLO: 123273178
FAS: 105268362
DAM: 107048280
CCIN: 107273290
SOY: 115877541
CSET: 123311489
AGB: 108909727
LDC: 111506485
PPYR: 116171384
OTU: 111420509
MSEX: 115445321
BANY: 112049326
PPOT: 106109968
PXU: 106127598
PRAP: 110991271
SLIU: 111352211
OFU: 114350146
HHAL: 106683676
DMK: 116928379
PJA: 122246518
PCHN: 125029993
HAME: 121859250
PTRU: 123502768
HAZT: 108679007
PPOI: 119114903
DSV: 119442997
RSAN: 119388179
RMP: 119186406
DFR: 124496718
SDM: 118184866
CEL: CELE_F26H9.6(rab-5)
CBR: CBG_19476
BMY: BM_BM13659(Bma-rab-5.1)
BGT: 106063407
GAE: 121387060
PMAX: 117317823
MMER: 123539481
OBI: 106869935
PDAM: 113679723
ALY: 9312341
CRB: 17887276
BRP: 103841387
BOE: 106309686
RSZ: 108862342
CPAP: 110816637
PVY: 116127857
GRA: 105784750
GAB: 108482446
GSJ: 114413589
VUN: 114179593
CCAJ: 109803904
APRC: 113855409
ADU: 107478681
FVE: 101304121
PPER: 18769848
PMUM: 103340925
PAVI: 110768296
PDUL: 117633639
MDM: 103449068
HBR: 110637341
MESC: 110610541
QLO: 115976952
NSY: 104215016
HAN: 110896232
ECAD: 122598484
MING: 122071516
NCOL: 116252949
PDA: 103713777
AOF: 109822713
SMO: SELMODRAFT_449889(RabF1-1) SELMODRAFT_449890(RabF1-2)
DFA: DFA_08681(rabJ)
EHX: EMIHUDRAFT_521925(Rab5L-1) EMIHUDRAFT_79468(Rab50)
 » show all
Reference
  Authors
Hirota Y, Kuronita T, Fujita H, Tanaka Y
  Title
A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments.
  Journal
Biochem Biophys Res Commun 364:40-7 (2007)
DOI:10.1016/j.bbrc.2007.09.089
  Sequence
[hsa:5869]
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