KEGG   ORTHOLOGY: K07964Help
Entry
K07964                      KO                                     

Name
HPSE
Definition
heparanase [EC:3.2.1.166]
Pathway
ko00531  Glycosaminoglycan degradation
ko01100  Metabolic pathways
ko05205  Proteoglycans in cancer
Module
M00078  Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K07964  HPSE; heparanase
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K07964  HPSE; heparanase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K07964  HPSE; heparanase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.166  heparanase
     K07964  HPSE; heparanase
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Enzymes
   K07964  HPSE; heparanase
BRITE hierarchy
Other DBs
RN: R07811
GO: 0030305
CAZy: GH79
Genes
HSA: 10855(HPSE)
PTR: 461206(HPSE)
PPS: 100996218(HPSE)
GGO: 101150800(HPSE)
PON: 100448281(HPSE)
NLE: 100596185(HPSE)
MCC: 707583(HPSE)
MCF: 102123028(HPSE)
CSAB: 103235901(HPSE)
RRO: 104658833(HPSE)
RBB: 108531149(HPSE)
CJC: 100402671(HPSE)
SBQ: 101043067(HPSE)
MMU: 15442(Hpse)
MCAL: 110294241(Hpse)
MPAH: 110330557(Hpse)
RNO: 64537(Hpse)
MUN: 110553884(Hpse)
CGE: 100755610(Hpse)
NGI: 103744984(Hpse)
HGL: 101721140(Hpse)
CCAN: 109683307(Hpse)
OCU: 100101601(HPSE)
TUP: 102501533(HPSE)
CFA: 608707(HPSE)
VVP: 112919568(HPSE)
AML: 100470911(HPSE)
UMR: 103665420(HPSE)
UAH: 113263199(HPSE)
ORO: 101371822(HPSE)
FCA: 101090101(HPSE)
PTG: 102965445(HPSE)
PPAD: 109276572(HPSE)
AJU: 106987077(HPSE)
BTA: 281230(HPSE)
BOM: 102265641(HPSE)
BIU: 109560640(HPSE)
BBUB: 102395500(HPSE)
CHX: 102188207(HPSE)
OAS: 101118612(HPSE)
SSC: 100271932(HPSE)
CFR: 102517816(HPSE)
CDK: 105092018(HPSE)
BACU: 102999760(HPSE)
LVE: 103084178(HPSE)
OOR: 101283118(HPSE)
DLE: 111187577(HPSE)
PCAD: 102985869(HPSE)
ECB: 100061267(HPSE)
EPZ: 103549090(HPSE)
EAI: 106846420(HPSE)
MYB: 102245458(HPSE)
MYD: 102774009(HPSE)
MNA: 107537105(HPSE)
HAI: 109387924(HPSE)
DRO: 112317780(HPSE)
PALE: 102888805(HPSE)
RAY: 107516475(HPSE)
MJV: 108394108(HPSE)
LAV: 100676520(HPSE)
TMU: 101360212
MDO: 100026183(HPSE)
SHR: 100923804(HPSE)
PCW: 110209762(HPSE)
GGA: 373981(HPSE)
MGP: 100545679(HPSE)
CJO: 107313425(HPSE)
NMEL: 110399069(HPSE)
APLA: 101797825(HPSE)
ACYG: 106041934(HPSE)
TGU: 100218163(HPSE)
LSR: 110468522(HPSE)
SCAN: 103826088(HPSE)
GFR: 102040930(HPSE)
FAB: 101809526(HPSE)
PHI: 102109966(HPSE)
PMAJ: 107203573(HPSE)
CCAE: 111928869(HPSE)
CCW: 104697252(HPSE)
ETL: 114057759(HPSE)
FPG: 101912317(HPSE)
FCH: 102057366(HPSE)
CLV: 102085346(HPSE)
EGZ: 104127343(HPSE)
NNI: 104014988(HPSE)
ACUN: 113479584(HPSE)
PADL: 103919913(HPSE)
AAM: 106494822(HPSE)
ASN: 102369021
AMJ: 102571669(HPSE)
PSS: 102450514(HPSE)
CMY: 102946031(HPSE)
CPIC: 101942907(HPSE)
ACS: 100565376(hpse)
PVT: 110083349(HPSE)
PBI: 103050955(HPSE)
PMUR: 107303159(HPSE)
PMUA: 114604526(HPSE)
GJA: 107116059(HPSE)
XLA: 108719705(hpse.L)
XTR: 100145320(hpse)
NPR: 108804446(HPSE)
DRE: 563020(hpse)
SRX: 107722827(hpse)
SGH: 107589237(hpse) 107591750
IPU: 108278991(hpse)
PHYP: 113543026(hpse)
AMEX: 103027675(hpse)
EEE: 113570752(hpse)
TRU: 101076415(hpse)
LCO: 104939605(hpse)
NCC: 104957343
MZE: 101471023(hpse)
ONL: 100704102(hpse)
OLA: 101156941(hpse)
XMA: 102231016(hpse)
XCO: 114150028(hpse)
PRET: 103473150(hpse)
CVG: 107100851(hpse)
NFU: 107390264(hpse)
KMR: 108242518(hpse)
ALIM: 106524410(hpse)
CSEM: 103390393(hpse)
LCF: 108892286(hpse)
SDU: 111238027(hpse)
HCQ: 109517543(hpse) 109519583
BPEC: 110161656(hpse)
SASA: 106563622(hpse) 106568158
OTW: 112219520(hpse) 112257516
ELS: 105014724(hpse)
SFM: 108935179(hpse)
PKI: 111842231(hpse)
LCM: 102346905(HPSE)
CMK: 103187960(hpse)
RTP: 109935286(hpse)
CIN: 100178996
SPU: 586838
AME: 725623
BIM: 100745198
BTER: 105666557
CCAL: 108630640
OBB: 114877484
SOC: 105193112
MPHA: 105836142
AEC: 105154939
ACEP: 105626290
PBAR: 105430094
VEM: 105559915
HST: 105180876
DQU: 106751247
CFO: 105248467
LHU: 105671110
PGC: 109853681
OBO: 105281678
PCF: 106786988
NVI: 100113700
CSOL: 105368274
MDL: 103580115
TCA: 659639
ATD: 109608715
NVL: 108564172
BMOR: 100141461(Hepa)
PMAC: 106717291
PRAP: 110998158
HAW: 110374496
PXY: 105384116
API: 100572917
DNX: 107165408
AGS: 114122244
CLEC: 106664391
ZNE: 110830469
FCD: 110856956
PVM: 113827196
CSCU: 111641472
CRG: 105335864
MYI: 110448663
LAK: 106153669
HMG: 100212115
AQU: 100632989
LJA: Lj0g3v0146829.1(Lj0g3v0146829.1) Lj0g3v0146829.2(Lj0g3v0146829.2) Lj2g3v0609680.1(Lj2g3v0609680.1) Lj4g3v1683270.1(Lj4g3v1683270.1) Lj4g3v1683270.2(Lj4g3v1683270.2) Lj4g3v1946680.1(Lj4g3v1946680.1) Lj4g3v1946680.2(Lj4g3v1946680.2) Lj4g3v2298190.1(Lj4g3v2298190.1) Lj6g3v1093320.1(Lj6g3v1093320.1)
DOSA: Os02t0802200-01(Os02g0802200) Os03t0211700-01(Os03g0211700) Os06t0179000-01(Os06g0179000) Os07t0598400-01(Os07g0598400) Os12t0578400-01(Os12g0578400)
ATS: 109736222(LOC109736222) 109750281(LOC109750281) 109770916(LOC109770916) 109777268(LOC109777268) 109780669(LOC109780669)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kussie PH, Hulmes JD, Ludwig DL, Patel S, Navarro EC, Seddon AP, Giorgio NA, Bohlen P
  Title
Cloning and functional expression of a human heparanase gene.
  Journal
Biochem Biophys Res Commun 261:183-7 (1999)
DOI:10.1006/bbrc.1999.0962
  Sequence
[hsa:10855]
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