KEGG   ORTHOLOGY: K08208
Entry
K08208                      KO                                     

Name
SLC22A12, URAT1
Definition
MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Disease
H00948  Renal hypouricemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
   04147 Exosome
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K08208  SLC22A12, URAT1; MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Other DBs
GO: 0015143
TC: 2.A.1.19.11 2.A.1.19.14
Genes
HSA: 116085(SLC22A12)
PTR: 743768(SLC22A12)
PPS: 100992384(SLC22A12)
GGO: 101124776(SLC22A12)
PON: 100448949(SLC22A12)
NLE: 100603239(SLC22A12)
MCC: 717530(SLC22A12)
MCF: 102146441(SLC22A12)
CSAB: 103233185(SLC22A12)
RRO: 104673252(SLC22A12)
RBB: 108542822(SLC22A12)
CJC: 100403727(SLC22A12)
SBQ: 101052936(SLC22A12)
MMU: 20521(Slc22a12)
MCAL: 110285925
MPAH: 110334679
RNO: 365398(Slc22a12)
MUN: 110549333(Slc22a12)
CGE: 100756772(Slc22a12)
NGI: 103738785(Slc22a12)
CFA: 483761(SLC22A12)
VVP: 112924304(SLC22A12)
AML: 100463979(SLC22A12)
ORO: 101371050(SLC22A12)
ELK: 111150109
FCA: 101100592(SLC22A12)
PPAD: 109246676(SLC22A12)
AJU: 106981752
BTA: 526067
BOM: 102273515(SLC22A12)
BIU: 109554122(SLC22A12)
BBUB: 102392275(SLC22A12)
SSC: 100520540(SLC22A12)
ECB: 100055832(SLC22A12)
EPZ: 103565065(SLC22A12)
EAI: 106833672(SLC22A12)
MJV: 108396367(SLC22A12)
LAV: 100661855(SLC22A12)
TMU: 101348787
MDO: 100013502(SLC22A9) 100031325(SLC22A12)
SHR: 100928235
OAA: 100075618
 » show all
Reference
  Authors
Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H
  Title
Molecular identification of a renal urate anion exchanger that regulates blood urate levels.
  Journal
Nature 417:447-52 (2002)
DOI:10.1038/nature742
  Sequence
[hsa:116085]
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