KEGG   ORTHOLOGY: K08550Help
Entry
K08550                      KO                                     

Name
ESR1, NR3A1
Definition
estrogen receptor alpha
Pathway
ko01522  Endocrine resistance
ko04915  Estrogen signaling pathway
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04961  Endocrine and other factor-regulated calcium reabsorption
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05224  Breast cancer
Disease
H00031  Breast cancer
H02061  Estrogen resistance syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K08550  ESR1, NR3A1; estrogen receptor alpha
   04917 Prolactin signaling pathway
    K08550  ESR1, NR3A1; estrogen receptor alpha
   04919 Thyroid hormone signaling pathway
    K08550  ESR1, NR3A1; estrogen receptor alpha
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08550  ESR1, NR3A1; estrogen receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08550  ESR1, NR3A1; estrogen receptor alpha
   05205 Proteoglycans in cancer
    K08550  ESR1, NR3A1; estrogen receptor alpha
  09162 Cancer: specific types
   05224 Breast cancer
    K08550  ESR1, NR3A1; estrogen receptor alpha
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08550  ESR1, NR3A1; estrogen receptor alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08550  ESR1, NR3A1; estrogen receptor alpha
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08550  ESR1, NR3A1; estrogen receptor alpha
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen-like
    K08550  ESR1, NR3A1; estrogen receptor alpha
Nuclear receptors [BR:ko03310]
 3. Estrogen like
  3A. Estrogen receptor
   K08550  ESR1, NR3A1; estrogen receptor alpha
BRITE hierarchy
Other DBs
GO: 0030284
Genes
HSA: 2099(ESR1)
PTR: 463079(ESR1)
PPS: 100980011(ESR1)
GGO: 101138953(ESR1)
PON: 100441912(ESR1)
NLE: 100580202(ESR1)
MCC: 613025(ESR1)
MCF: 102115223(ESR1)
CSAB: 103240732(ESR1)
RRO: 104657857 104678360
RBB: 108539131(ESR1)
CJC: 100385918(ESR1)
MMU: 13982(Esr1)
MCAL: 110303039(Esr1)
MPAH: 110337903(Esr1)
RNO: 24890(Esr1)
CGE: 100768474(Esr1)
NGI: 103745757(Esr1)
HGL: 101715977(Esr1)
CCAN: 109682188(Esr1)
OCU: 100351261(ESR1)
TUP: 102497715(ESR1)
CFA: 403640(ESR1)
VVP: 112919529(ESR1)
AML: 100484518(ESR1)
UMR: 103666963(ESR1)
UAH: 113259567(ESR1)
ORO: 101376152(ESR1)
FCA: 552888(ESR1)
PTG: 102969728(ESR1)
PPAD: 109256413(ESR1)
AJU: 106976266(ESR1)
BTA: 407238(ESR1)
BOM: 102266924(ESR1)
BIU: 109563584(ESR1)
BBUB: 102408657(ESR1)
CHX: 102189484(ESR1)
OAS: 443228(ESR1)
SSC: 397435(ESR1)
CFR: 102519728(ESR1)
CDK: 105100955(ESR1)
BACU: 103009601(ESR1)
LVE: 103069191(ESR1)
OOR: 101279259(ESR1)
DLE: 111167007(ESR1)
PCAD: 102978428(ESR1)
ECB: 791249(ESR1)
EPZ: 103547564(ESR1)
EAI: 106822682(ESR1)
MYB: 102261068(ESR1)
MYD: 102765890(ESR1)
MNA: 107535956(ESR1)
HAI: 109380859(ESR1)
DRO: 112297404(ESR1)
PALE: 102877910(ESR1)
RAY: 107513028(ESR1)
MJV: 108405771(ESR1)
LAV: 100677316(ESR1)
TMU: 101351018
MDO: 100027187(ESR1)
SHR: 100935401(ESR1)
PCW: 110208556(ESR1)
GGA: 396099(ESR1)
MGP: 100542782(ESR1)
CJO: 107311566(ESR1)
NMEL: 110390765(ESR1)
APLA: 101802318(ESR1)
ACYG: 106034288(ESR1)
TGU: 751998(ESR1)
LSR: 110476028(ESR1)
SCAN: 103820578(ESR1)
GFR: 102032661(ESR1)
FAB: 101819288(ESR1)
PHI: 102108976(ESR1)
PMAJ: 107201411(ESR1)
CCAE: 111926710(ESR1)
CCW: 104690175(ESR1)
ETL: 114069851(ESR1)
FPG: 101918191(ESR1)
FCH: 102046059(ESR1)
CLV: 102095459(ESR1)
EGZ: 104131114(ESR1) 104133553
NNI: 104013764(ESR1)
ACUN: 113478628(ESR1)
PADL: 103917043(ESR1)
AAM: 106496902(ESR1)
ASN: 102376369(ESR1)
AMJ: 102564196(ESR1)
PSS: 102456765(ESR1)
CMY: 102934699(ESR1)
CPIC: 101933533(ESR1)
ACS: 100337547(esr1)
PVT: 110085184(ESR1)
PMUR: 107292771(ESR1)
TSR: 106549259 106552445(ESR1)
PMUA: 114594259(ESR1)
GJA: 107123010(ESR1)
XLA: 398733(esr1.S) 398734(esr1.L)
XTR: 394461(esr1)
NPR: 108790124(ESR1)
DRE: 259252(esr1)
SRX: 107737325
SANH: 107659219
IPU: 100304474(esr1)
PHYP: 113532161(esr1)
AMEX: 103043741
EEE: 113570417
TRU: 101077800(esr1)
LCO: 104931018(esr1)
NCC: 104962265 104965323(esr1)
MZE: 101479381
ONL: 100534514(ER)
OLA: 101162413(esr1)
XMA: 102235986(esr1)
XCO: 114158784(esr1)
PRET: 103457510(esr1)
CVG: 107081657 107101861(esr1)
NFU: 107377558
KMR: 108240123(esr1)
ALIM: 106519793(esr1)
AOCE: 111571044
CSEM: 103380669
POV: 109636049(esr1)
LCF: 108880883
SDU: 111236823(esr1)
SLAL: 111655594(esr1)
HCQ: 109531021(esr1)
BPEC: 110175149(esr1)
MALB: 109952736
SASA: 100136461(esr1) 100846971
SALP: 111954041 111972669(esr1)
ELS: 105017493(esr1)
SFM: 108921694(esr1)
PKI: 111858013
CMK: 103179230(esr1)
RTP: 109913159(esr1) 109934132
SKO: 102800833
PCAN: 112569923
CRG: 105326453
OBI: 106879341
LAK: 106169611
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nilsson S, Gustafsson JA
  Title
Estrogen receptors: therapies targeted to receptor subtypes.
  Journal
Clin Pharmacol Ther 89:44-55 (2011)
DOI:10.1038/clpt.2010.226
Reference
PMID:3754034
  Authors
Green S, Walter P, Kumar V, Krust A, Bornert JM, Argos P, Chambon P
  Title
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A.
  Journal
Nature 320:134-9 (1986)
DOI:10.1038/320134a0
  Sequence
[hsa:2099]
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