KEGG   ORTHOLOGY: K08645
Entry
K08645                      KO                                     
Symbol
lef
Name
anthrax lethal toxin endopeptidase [EC:3.4.24.83]
Pathway
map04621  NOD-like receptor signaling pathway
Module
M00859  Bacillus anthracis pathogenicity signature, anthrax toxin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K08645  lef; anthrax lethal toxin endopeptidase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08645  lef; anthrax lethal toxin endopeptidase
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K08645  lef; anthrax lethal toxin endopeptidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.83  anthrax lethal factor endopeptidase
     K08645  lef; anthrax lethal toxin endopeptidase
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M34: anthrax lethal factor family
   K08645  lef; anthrax lethal toxin endopeptidase
Bacterial toxins [BR:ko02042]
 Type III toxins: Intracellular toxins
  Metalloprotease
   Anthrax lethal toxin
    K08645  lef; anthrax lethal toxin endopeptidase
Genes
BAR: GBAA_pXO1_0172(lef)
BAH: BAMEG_A0165(lef)
BAI: BAA_A0173(lef)
BAX: H9401_5641
BANT: A16_60375
BANR: A16R_61395
BANS: BAPAT_pXO10166
BANH: HYU01_28805
BANV: DJ46_5660(lef)
BCX: BCA_A0154(lef)
BAL: BACI_pCIXO101600(lef)
BRW: GOP56_07280
 » show all
Reference
PMID:2509294
  Authors
Bragg TS, Robertson DL
  Title
Nucleotide sequence and analysis of the lethal factor gene (lef) from Bacillus anthracis.
  Journal
Gene 81:45-54 (1989)
DOI:10.1016/0378-1119(89)90335-1
  Sequence
[bar:GBAA_pXO1_0172]
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