KEGG   ORTHOLOGY: K10163
Entry
K10163                      KO                                     
Symbol
FOXP3, IPEX
Name
forkhead box P3
Pathway
map04659  Th17 cell differentiation
map05321  Inflammatory bowel disease
Disease
H00107  Other well-defined immunodeficiency syndromes
H00512  Permanent neonatal diabetes mellitus
H01971  IPEX syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K10163  FOXP3, IPEX; forkhead box P3
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    K10163  FOXP3, IPEX; forkhead box P3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K10163  FOXP3, IPEX; forkhead box P3
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    K10163  FOXP3, IPEX; forkhead box P3
Genes
HSA: 50943(FOXP3)
PTR: 740909(FOXP3)
PPS: 100990082(FOXP3)
GGO: 101130276(FOXP3)
PON: 100432872(FOXP3)
NLE: 100606735(FOXP3)
MCC: 574303(FOXP3)
MCF: 102120882(FOXP3)
CSAB: 103231966(FOXP3)
CATY: 105573104(FOXP3)
PANU: 101018460(FOXP3)
TGE: 112616491(FOXP3)
RRO: 104661817(FOXP3)
RBB: 108521365(FOXP3)
TFN: 117083982(FOXP3)
PTEH: 111535206(FOXP3)
CJC: 100408633(FOXP3)
SBQ: 101035423(FOXP3)
CSYR: 103277254(FOXP3)
MMUR: 105856420(FOXP3)
LCAT: 123628133(FOXP3)
OGA: 100963348(FOXP3)
MMU: 20371(Foxp3)
MCAL: 110286217(Foxp3)
MPAH: 110313390(Foxp3)
RNO: 317382(Foxp3)
MCOC: 116102278(Foxp3)
MUN: 110561916(Foxp3)
CGE: 100757421(Foxp3)
MAUA: 101829655(Foxp3)
PLEU: 114701283(Foxp3)
MORG: 121444336(Foxp3)
AAMP: 119805251(Foxp3)
NGI: 103741675(Foxp3)
HGL: 101722447(Foxp3)
CPOC: 100735602(Foxp3)
CCAN: 109697194(Foxp3)
DORD: 105997836(Foxp3)
DSP: 122098784(Foxp3)
NCAR: 124971755
OCU: 100348270(FOXP3)
OPI: 101520267(FOXP3)
TUP: 102482059(FOXP3)
CFA: 491876(FOXP3)
VVP: 112907239(FOXP3)
VLG: 121483416(FOXP3)
AML: 100467988(FOXP3)
UMR: 103667451(FOXP3)
UAH: 113265955(FOXP3)
UAR: 123797190(FOXP3)
ELK: 111150492
LLV: 125091733
MPUF: 101690558(FOXP3)
ORO: 101365686(FOXP3)
EJU: 114216722(FOXP3)
ZCA: 113931543(FOXP3)
MLX: 118010407(FOXP3)
FCA: 100037405(FOXP3)
PYU: 121026063(FOXP3)
PBG: 122477614(FOXP3)
PTG: 102972991(FOXP3)
PPAD: 109248099(FOXP3)
AJU: 106989015(FOXP3)
HHV: 120221005(FOXP3)
BTA: 506053(FOXP3)
BOM: 102285670(FOXP3)
BIU: 109555264(FOXP3)
BBUB: 102405704(FOXP3)
CHX: 102188755(FOXP3)
OAS: 100240742(FOXP3)
ODA: 120882131(FOXP3)
CCAD: 122434758(FOXP3)
SSC: 444998(FOXP3)
CFR: 102505184(FOXP3)
CBAI: 105079416(FOXP3)
CDK: 105106315(FOXP3)
VPC: 102541841(FOXP3)
BACU: 102998254(FOXP3)
LVE: 103083465(FOXP3)
OOR: 101280345(FOXP3)
DLE: 111169472(FOXP3)
PCAD: 102993238(FOXP3)
PSIU: 116747498(FOXP3)
ECB: 100052226(FOXP3)
EPZ: 103545451(FOXP3)
EAI: 106826960(FOXP3)
MYB: 102259977(FOXP3)
MYD: 102770845(FOXP3)
MMYO: 118654732(FOXP3)
MLF: 102434633(FOXP3)
MNA: 107541386(FOXP3)
PKL: 118731819(FOXP3)
HAI: 109374800(FOXP3)
DRO: 112322442(FOXP3)
SHON: 118998348(FOXP3)
AJM: 119059501(FOXP3)
PDIC: 114505049(FOXP3)
PHAS: 123832835(FOXP3)
MMF: 118635901(FOXP3)
RFQ: 117028933(FOXP3)
PALE: 102882840(FOXP3)
PGIG: 120587069(FOXP3)
PVP: 105309050(FOXP3)
RAY: 107515002(FOXP3)
MJV: 108404218(FOXP3)
TOD: 119246157(FOXP3)
SARA: 101549177(FOXP3)
LAV: 100667999(FOXP3)
TMU: 101361863
DNM: 101446573(FOXP3)
MDO: 100019598(FOXP3)
GAS: 123254380(FOXP3)
SHR: 100928075(FOXP3)
PCW: 110201010(FOXP3)
OAA: 100075823(FOXP3)
LSR: 110482650(FOXP3)
OTC: 121340074
PHI: 102110738(FOXP3)
ACHC: 115338228
ASN: 102376811(FOXP3)
CMY: 114022693(FOXP3)
CABI: 116838402
MRV: 120388184(FOXP3)
ACS: 103277757(foxp3)
PVT: 110078611(FOXP3)
SUND: 121922705(FOXP3)
PBI: 103050763
PGUT: 117675531(FOXP3)
VKO: 123029961
PMUA: 114587352(FOXP3)
ZVI: 118097597(FOXP3)
STOW: 125430334
XLA: 100158268(foxp3.L) 108700514(foxp3.S)
XTR: 100485747(foxp3)
NPR: 108788500(FOXP3)
RTEM: 120913035(FOXP3)
BBUF: 120977794(FOXP3)
BGAR: 122919316(FOXP3)
DRE: 101886699(foxp3b)
PPRM: 120469066(foxp3b)
MAMB: 125279769(foxp3b)
IPU: 108264896(foxp3b)
SMEO: 124399423(foxp3b)
TFD: 113655942(foxp3b)
AMEX: 103040869(foxp3)
EEE: 113579121
TRU: 101070400
LCO: 104932792
NCC: 104956470
CGOB: 115016671
ELY: 117258034(foxp3b)
PLEP: 121947415(foxp3b)
SLUC: 116050885(foxp3b)
ECRA: 117948031(foxp3b)
PFLV: 114558978
GAT: 120828973
PPUG: 119223723
MSAM: 119904976
CUD: 121517864(foxp3b)
ALAT: 119022827(foxp3b)
MZE: 101474386(foxp3)
ONL: 100707959(foxp3)
OAU: 116323397(foxp3b)
OLA: 101163234
OML: 112140034(foxp3b)
XMA: 102225546
XCO: 114142250
XHE: 116721316
PRET: 103466967
PFOR: 103154220
PLAI: 106957134
PMEI: 106928338
CVG: 107091006
CTUL: 119786884
GMU: 124879567
KMR: 108231982
ALIM: 106527394
NWH: 119417247
AOCE: 111576081
CSEM: 103384892
POV: 109630697
SSEN: 122776590(foxp3b)
HHIP: 117765143(foxp3b)
HSP: 118111056(foxp3b)
LCF: 108900475
SDU: 111219161
SLAL: 111670617
XGL: 120804014(foxp3b)
MALB: 109965199
BSPL: 114859437(foxp3b)
SASA: 100526661(foxp3)
OTW: 112222058(foxp3b)
OMY: 100653438(foxp3-2) 100653439(foxp3-1)
SALP: 111976461
SNH: 120058955 120060722(foxp3b)
ELS: 105013833
SFM: 108934796(foxp3)
PKI: 111847802(foxp3)
PSPA: 121328315
ARUT: 117404293
LCM: 102353004(FOXP3)
 » show all
Reference
  Authors
Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, Wilkinson JE, Galas D, Ziegler SF, Ramsdell F
  Title
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
  Journal
Nat Genet 27:68-73 (2001)
DOI:10.1038/83784
  Sequence
[hsa:50943]
Reference
  Authors
Mu J, Tai X, Iyer SS, Weissman JD, Singer A, Singer DS
  Title
Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function.
  Journal
J Immunol 192:2892-903 (2014)
DOI:10.4049/jimmunol.1302847
  Sequence
[mmu:20371]
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