KEGG ORTHOLOGY: K10348

ORTHOLOGY: K10348

Entry

K10348                      KO

Symbol

LRR1, PPIL5

Name

LRR-repeat protein 1

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10348  LRR1, PPIL5; LRR-repeat protein 1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul2 complex
    Target recognizing subunit
     K10348  LRR1, PPIL5; LRR-repeat protein 1

Genes

HSA:	122769(LRR1)

PTR:	741219(LRR1)

PPS:	100985545(LRR1)

GGO:	101128313(LRR1)

PON:	100460928(LRR1)

PPYG:

129012875(LRR1)

NLE:	100595298(LRR1)

HMH:	116456187(LRR1)

SSYN:

129487937(LRR1)

MCC:	706658(LRR1)

MCF:	102131515(LRR1)

MTHB:

126958518

MNI:	105481865(LRR1)

CSAB:

103228937(LRR1)

CATY:

105599037(LRR1)

PANU:

100998170(LRR1)

TGE:	112628479(LRR1)

MLEU:

105554524(LRR1)

RRO:	104682763(LRR1)

RBB:	108513670(LRR1)

TFN:	117069690(LRR1)

PTEH:

111549513(LRR1)

CANG:

105515276(LRR1)

CJC:	100407227(LRR1)

SBQ:	101053110(LRR1)

CIMI:

108287962(LRR1)

ANAN:

105719947(LRR1)

CSYR:

103254185(LRR1)

MMUR:

105867652(LRR1)

LCAT:

123649635(LRR1)

PCOQ:

105825895(LRR1)

OGA:	100946626(LRR1)

MMU:	69706(Lrr1)

MCAL:

110307367(Lrr1)

MPAH:

110324586(Lrr1)

RNO:	685860(Lrr1)

MCOC:

116080593(Lrr1)

ANU:	117717160(Lrr1)

MUN:	110556921(Lrr1)

CGE:	100752788(Lrr1)

MAUA:

101841888(Lrr1)

PROB:

127230643(Lrr1)

PLEU:

114684699(Lrr1)

MORG:

121452392(Lrr1)

MFOT:

126508426

AAMP:

119819385(Lrr1)

NGI:	103731529(Lrr1)

HGL:	101708337(Lrr1)

CPOC:

100719517(Lrr1)

CCAN:

109693273(Lrr1)

DORD:

105982614(Lrr1)

DSP:	122106457(Lrr1)

PLOP:

125363206(Lrr1)

NCAR:

124978272

MMMA:

107146818(Lrr1)

OCU:

100348169

OPI:	101529285(LRR1)

TUP:	102471625(LRR1)

GVR:	103586059(LRR1)

CFA:	490676(LRR1)

CLUD:

112657180(LRR1)

VVP:	112921464(LRR1)

VLG:	121492788(LRR1)

NPO:	129495846(LRR1)

AML:	100469682(LRR1)

UMR:	103665584(LRR1)

UAH:	113266193(LRR1)

UAR:	123793390(LRR1)

ELK:

111161166

LLV:

125105032

MPUF:

101670262(LRR1)

MNP:	131998815(LRR1)

MLK:	131836525(LRR1)

NVS:	122893473(LRR1)

ORO:	101381296(LRR1)

EJU:	114211111(LRR1)

ZCA:	113908676(LRR1)

MLX:	118002219(LRR1)

NSU:	110590693(LRR1)

LWW:	102746941(LRR1)

FCA:	101091630(LRR1)

PYU:	121031721(LRR1)

PCOO:

112856256(LRR1)

PBG:	122469054(LRR1)

PVIV:

125168695(LRR1)

LRUF:

124512341

PTG:	102957954(LRR1)

PPAD:

109268520(LRR1)

PUC:

125909529

AJU:

106985102

HHV:	120220265(LRR1)

BTA:	790210(LRR1)

BOM:	102281247(LRR1)

BIU:	109565005(LRR1)

BBUB:

102407570(LRR1)

BBIS:

104990274(LRR1)

CHX:	102188504(LRR1)

OAS:	101119991(LRR1)

BTAX:

128054563(LRR1)

ODA:	120853132(LRR1)

CCAD:

122443450(LRR1)

MBEZ:

129562396(LRR1)

SSC:	100518890(LRR1)

CFR:	102519283(LRR1)

CBAI:

105078444(LRR1)

CDK:	105091397(LRR1)

VPC:	102543526(LRR1)

BACU:

103017144(LRR1)

BMUS:

118888760(LRR1)

LVE:	103084358(LRR1)

OOR:	101281239(LRR1)

DLE:	111173190(LRR1)

PCAD:

102977429(LRR1)

PSIU:

116750021(LRR1)

NASI:

112415080(LRR1)

ECB:	100065715(LRR1)

EPZ:	103556136(LRR1)

EAI:	106839812(LRR1)

MYB:	102251422(LRR1)

MYD:	102755811(LRR1)

MMYO:

118674979(LRR1)

MLF:	102441812(LRR1)

MDT:	132212981(LRR1)

PKL:	118721068(LRR1)

EFUS:

103294979(LRR1)

MNA:	107537516(LRR1)

DRO:	112301675(LRR1)

SHON:

118987807(LRR1)

AJM:	119036789(LRR1)

PDIC:

114493191(LRR1)

PHAS:

123825244(LRR1)

MMF:	118634890(LRR1)

PPAM:

129078130(LRR1)

HAI:	109393311(LRR1)

RFQ:	117022877(LRR1)

PALE:

102884951(LRR1)

PGIG:

120597935(LRR1)

PVP:	105302805(LRR1)

RAY:	107518870(LRR1)

MJV:	108406357(LRR1)

TOD:	119239060(LRR1)

SARA:

101553310(LRR1)

SETR:

125999303(LRR1)

LAV:	100673366(LRR1)

TMU:

101344595

ETF:	101641996(LRR1)

DNM:	101427259(LRR1)

MDO:	100028925(LRR1)

SHR:	100924009(LRR1)

AFZ:

127549678

PCW:	110220656(LRR1)

TVP:	118829072(LRR1)

OAA:	100084469(LRR1)

GGA:	423565(LRR1)

PCOC:

116234576(LRR1)

MGP:	100539301(LRR1)

CJO:	107315498(LRR1)

TPAI:

128087216(LRR1)

LMUT:

125695093(LRR1)

NMEL:

110401578(LRR1)

APLA:

119717106

ACYG:

106046978(LRR1)

CATA:

118250367(LRR1)

AFUL:

116490396(LRR1) 116500957

TGU:	100221887(LRR1)

LSR:	110473475(LRR1)

SCAN:

103823819(LRR1)

PMOA:

120497050(LRR1)

OTC:	121339011(LRR1)

PRUF:

121348711(LRR1)

GFR:	102034328(LRR1)

FAB:	101807579(LRR1)

OMA:	130253544(LRR1)

PHI:	102099833(LRR1)

PMAJ:

107206380(LRR1)

CCAE:

111929631(LRR1)

CCW:	104695885(LRR1)

CBRC:

103618915(LRR1)

ETL:	114069219(LRR1)

ZLE:	135449247(LRR1)

ACHL:

103810238(LRR1)

SVG:	106858967(LRR1)

MMEA:

130583796(LRR1)

HRT:	120754646(LRR1)

SATI:

136362695(LRR1)

FPG:	101914087(LRR1)

FCH:	102059805(LRR1)

CCRI:

104164242(LRR1)

NNT:	104399209(LRR1)

SHAB:

115607698(LRR1)

ACUN:

113480378(LRR1)

TALA:

104358207(LRR1)

ACHC:

115337011(LRR1)

HALD:

104313299(LRR1)

HLE:	104839454(LRR1)

AGEN:

126050585

GCL:

127016851

CSTI:

104549320(LRR1)

LDI:	104348334(LRR1)

MNB:	103772281(LRR1)

DPUB:

104299367(LRR1)

AVIT:

104267197(LRR1)

BRHI:

104501307(LRR1)

EGZ:	104135004(LRR1)

NNI:	104019497(LRR1)

PCRI:

104024239(LRR1)

PCAO:

104048264(LRR1)

PADL:

103914913(LRR1)

AFOR:

103907696(LRR1)

FGA:	104081338(LRR1)

GSTE:

104263078(LRR1)

CLV:	102088738(LRR1)

MUI:	104533581(LRR1)

PGUU:

104465970(LRR1)

PLET:

104613837(LRR1)

EHS:	104514799(LRR1)

CMAC:

104473246(LRR1)

CUCA:

104057448(LRR1)

TEO:	104380753(LRR1)

BREG:

104634704(LRR1)

OHA:	104327791(LRR1)

ACAR:

104517730(LRR1)

CPEA:

104394770(LRR1)

CVF:	104294332(LRR1)

RTD:	128909154(LRR1)

AAM:	106487025(LRR1)

AROW:

112961227(LRR1)

NPD:	112957767(LRR1)

TGT:	104565982(LRR1)

DNE:	112994109(LRR1)

SCAM:

104145470(LRR1)

ASN:	102379288(LRR1)

AMJ:	102562104(LRR1)

CPOO:

109320899(LRR1)

GGN:	109299271(LRR1)

PSS:	102447416(LRR1)

CMY:	102940177(LRR1)

CCAY:

125639200(LRR1)

DCC:	119857965(LRR1)

CPIC:

101942405(LRR1)

TST:	117876097(LRR1)

CABI:

116818091(LRR1)

MRV:	120405105(LRR1)

ACS:	100553406(lrr1)

ASAO:

132760692(LRR1)

PVT:	110070672(LRR1)

SUND:

121919643(LRR1)

PBI:	103051219(LRR1)

PMUR:

107298228(LRR1)

CTIG:

120301835(LRR1)

TSR:	106545955(LRR1)

PGUT:

117675035(LRR1)

APRI:

131187951(LRR1)

PTEX:

113435157(LRR1)

NSS:	113414142(LRR1)

VKO:	123026586(LRR1)

PMUA:

114591780(LRR1)

PRAF:

128411334(LRR1)

ZVI:	118097723(LRR1)

HCG:	128332228(LRR1)

GJA:	107122507(LRR1)

STOW:

125427107(LRR1)

EMC:	129323472(LRR1)

XLA:	432125(lrr1.L)

XTR:	394892(lrr1)

NPR:	108786871(LRR1)

RTEM:

120921165(LRR1)

BBUF:

120981903(LRR1)

MUO:	115478091(LRR1)

GSH:	117364263(LRR1)

DRE:	404617(lrr1)

SRX:	107732028 107748237(lrr1)

SANH:

107660558(lrr1)

SGH:	107573111(lrr1) 107573727

CCAR:

109093245(lrr1)

CAUA:

113074533

CGIB:

127933173

PTET:

122334462(lrr1)

LROH:

127179248(lrr1)

OMC:	131523543(lrr1)

PPRM:

120477712(lrr1)

RKG:	130071851(lrr1)

MAMB:

125269200(lrr1)

CIDE:

127498509

CERY:

137006230(lrr1)

MASI:

127454844 127455266

TROS:

130559987(lrr1)

TDW:	130436600(lrr1)

MANU:

129417088(lrr1)

IPU:

108269824

IFU:	128613147(lrr1)

PHYP:

113529716(lrr1)

SMEO:

124390583(lrr1)

TFD:	113660317(lrr1)

TVC:	132852837(lrr1)

TRN:	134325574(lrr1)

AMEX:

103039453(lrr1)

CMAO:

118823976(lrr1)

EEE:	113587277(lrr1)

CHAR:

105899688(lrr1)

TRU:	101072535(lrr1)

TFS:	130539955(lrr1)

TNG:	GSTEN00032190G001

LCO:	104922129(lrr1)

NCC:	104953600(lrr1)

TBEN:

117478757(lrr1)

CGOB:

115027811(lrr1)

PGEO:

117467864(lrr1)

GACU:

117549847(lrr1)

EMAC:

134882032(lrr1)

ELY:	117266792(lrr1)

EFO:	125900373(lrr1)

PLEP:

121954121(lrr1)

SLUC:

116035750(lrr1)

ECRA:

117935924(lrr1)

ESP:	116670264(lrr1)

PFLV:

114547035(lrr1)

GAT:	120832488(lrr1)

PPUG:

119227943(lrr1)

AFB:	129103652(lrr1)

CLUM:

117751372(lrr1)

PSWI:

130191618 130201403

MSAM:

119910502(lrr1)

SCHU:

122861556(lrr1)

CUD:	121526189(lrr1)

ALAT:

119034419(lrr1)

MZE:	101472684(lrr1)

ONL:	100690758(lrr1)

OAU:	116334753(lrr1)

OLA:	101170558(lrr1)

OML:	112148813(lrr1)

CSAI:

133462034(lrr1)

XMA:	102216368(lrr1)

XCO:	114134517(lrr1)

XHE:	116709416(lrr1)

PRET:

103458869(lrr1)

PFOR:

103144240(lrr1)

PLAI:

106954179(lrr1)

PMEI:

106926880(lrr1)

GAF:	122846471(lrr1)

PPRL:

129374734(lrr1)

CVG:	107087555(lrr1)

CTUL:

119784278(lrr1)

GMU:	124884910(lrr1)

NFU:	107392275(lrr1)

KMR:	108232943(lrr1)

ALIM:

106521718(lrr1)

NWH:	119427181(lrr1)

AOCE:

111565943(lrr1)

MCEP:

125024094(lrr1)

CSEM:

103377509(lrr1)

POV:	109645482(lrr1)

SSEN:

122783033(lrr1)

HHIP:

117755839(lrr1)

HSP:	118116958(lrr1)

PPLT:

128451426(lrr1)

SMAU:

118285694(lrr1)

LCF:

108888130

SDU:	111226186(lrr1)

SLAL:

111644733(lrr1)

XGL:	120795674(lrr1)

HCQ:	109526122(lrr1)

SSCV:

125980387

SBIA:

133513743(lrr1)

PEE:	133413073(lrr1)

PTAO:

133487483(lrr1)

BPEC:

110155277(lrr1)

MALB:

109955099(lrr1)

BSPL:

114848265(lrr1)

SJO:	128375376(lrr1)

SASA:

100380543(lrr1)

STRU:

115172910(lrr1)

OTW:	112262098(lrr1)

OMY:	110498191(lrr1)

OGO:	124001816(lrr1)

ONE:	115146452(lrr1)

OKI:	109894700(lrr1)

OKE:	118362240(lrr1)

SALP:

111968947(lrr1)

SNH:	120059791(lrr1)

CCLU:

121539026(lrr1)

ELS:	105015981(lrr1)

SFM:	108941418(lrr1)

PKI:	111852434(lrr1)

AANG:

118231425(lrr1)

LOC:	102696512(lrr1)

PSPA:

121324270(lrr1) 121330150

ARUT:

117421898 117425157

PSEX:

120518637(lrr1)

LCM:	102352582(LRR1)

CMK:	103175355(lrr1)

RTP:	109932780(lrr1)

CPLA:

122553499(lrr1)

HOC:	132817954(lrr1)

LERI:

129700530(lrr1)

PMRN:

116948373(LRR1)

LRJ:	133352816(LRR1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG6098(Lrr47)

DER:

6543329

DSE:

6612021

DSI:	Dsimw501_GD23713(Dsim_GD23713)

DYA:	Dyak_GE18468

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:	111519768 124460837 124461266 124461267 124461403 124461492 124461697 26529335 26530056 6637527 6641875 6642619 6653594

DGR:

6562164

DMO:	Dmoj_GI23304

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119662004 119662020 119689973

MDE:	101896228 131801818

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ013147

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

105426676 105429181 105431178

VEM:	105561070 105561516 105569532

HST:

DQU:

CFO:

FEX:

LHU:	105668810 105679435

PGC:	109852130 109856134 109857887 109862083 109862774

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

115440087 119188635 119191614

DPL:	KGM_204584

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:

DNX:	107161877 107167494 107168050

AGS:	114128620 114128801

RMD:	113551148 113555647 113557221 113557228 113557261 113557328 113558598 113559697

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106684445(Lrr47)

NLU:

111051291

HVI:	124360729 124361528

MQU:

128993293

PHU:	Phum_PHUM044600

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_63134

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:	128689904 128689973

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

CVS:	136970585(Lrr47)

PTEP:

107438793 107450040

ABRU:

129965941

UDV:	129224250 129224268

SDM:

118186101

LPOL:

106468192

CEL:	CELE_F33G12.4(lrr-1)

CBR:	CBG_02302(Cbr-lrr-1)

CRQ:	GCK72_005934

NAI:	NECAME_14280

BMY:	BM_BM16925(Bma-lrr-1)

LOA:	LOAG_07157

HRO:	HELRODRAFT_186045

LGI:	LOTGIDRAFT_185863

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_173420

SHX:	MS3_00009879(LRRK1) MS3_00010138(LRR1)

OVI:	T265_13047

EGL:	EGR_03784 EGR_08916

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_52818

AQU:

100636187

MBR:	MONBRDRAFT_29815

SRE:	PTSG_02737

» show all

Reference

PMID:15601820

Authors

Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.

Title

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Journal

Genes Dev 18:3055-65 (2004)
DOI:10.1101/gad.1252404

Sequence

[hsa:122769]

LinkDB

DBGET integrated database retrieval system