KEGG   ORTHOLOGY: K10393
Entry
K10393                      KO                                     

Name
KIF2_24, MCAK
Definition
kinesin family member 2/24
Pathway
ko04361  Axon regeneration
Disease
H01881  Complex cortical dysplasia with other brain malformations
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    K10393  KIF2_24, MCAK; kinesin family member 2/24
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K10393  KIF2_24, MCAK; kinesin family member 2/24
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K10393  KIF2_24, MCAK; kinesin family member 2/24
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     K10393  KIF2_24, MCAK; kinesin family member 2/24
  Centrosome formation and ciliogenesis proteins
   Spindle formation proteins
    K10393  KIF2_24, MCAK; kinesin family member 2/24
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Kinesins
     K10393  KIF2_24, MCAK; kinesin family member 2/24
Other DBs
GO: 0003777
Genes
HSA: 11004(KIF2C) 347240(KIF24) 3796(KIF2A) 84643(KIF2B)
PTR: 100615381(KIF2A) 100615451(KIF24) 456548(KIF2C) 468409(KIF2B)
PPS: 100969140(KIF24) 100971992(KIF2C) 100977640(KIF2A) 100977690(KIF2B)
GGO: 101127233(KIF2B) 101143402(KIF2C) 101150441(KIF2A) 101150995
PON: 100174485(KIF2A) 100446908(KIF2B) 100458803(KIF24) 100461300(KIF2C)
NLE: 100587830(KIF24) 100590717(KIF2C) 100594029(KIF2A) 100594853(KIF2B)
MCC: 696561(KIF2A) 701030(KIF24) 705381(KIF2C) 705683(KIF2B)
MCF: 102116400(KIF2A) 102130803(KIF2B) 102134753(KIF2C) 102143708(KIF24)
CSAB: 103219271(KIF24) 103222124(KIF2A) 103224934(KIF2C) 103242904(KIF2B)
RRO: 104657603(KIF2B) 104669057(KIF2C) 104679552(KIF2A) 104679996(KIF24)
RBB: 108514409(KIF2A) 108522462(KIF2B) 108535670(KIF2C) 108542173(KIF24)
CJC: 100391603(KIF2C) 100400693(KIF24) 100401329(KIF2A) 100401743(KIF2B)
SBQ: 101033316(KIF2C) 101039814(KIF2B) 101041635(KIF24) 101043199(KIF2A)
MMU: 109242(Kif24) 16563(Kif2a) 73470(Kif2b) 73804(Kif2c)
MCAL: 110292789(Kif24) 110293187(Kif2c) 110305088(Kif2b) 110307959(Kif2a)
MPAH: 110322988(Kif2c) 110329193(Kif2a) 110332383(Kif2b) 110338730(Kif24)
RNO: 171529(Kif2c) 287624(Kif2b) 313170(Kif24) 364670(RGD1559908) 84391(Kif2a)
MUN: 110546524(Kif2c) 110547124(Kif24) 110563943(Kif2a) 110566200(Kif2b)
CGE: 100689309(Kif2c) 100756108(Kif2a) 100760507(Kif2b) 100770944(Kif24)
NGI: 103730323 103738410(Kif2b) 103741580(Kif24) 103743883(Kif2c) 103752512(Kif2a)
HGL: 101699053(Kif2b) 101699156(Kif24) 101700436(Kif2c) 101722153(Kif2a)
CCAN: 109679199(Kif2b) 109686498(Kif24) 109698968(Kif2c) 109700888(Kif2a)
OCU: 100338593(KIF2B) 100343439(KIF24) 100349671(KIF2C) 100354534(KIF2A) 103345648
TUP: 102472953(KIF2A) 102478446(KIF2B) 102486251(KIF24) 102498642(KIF2C)
CFA: 102156876(KIF2B) 475382(KIF2C) 478071(KIF2A) 481585(KIF24)
VVP: 112913768 112914808(KIF2C) 112918138(KIF2B) 112927544(KIF24) 112935472(KIF2A)
AML: 100466369(KIF24) 100468186(KIF2B) 100471340(KIF2A) 100474833(KIF2C)
UMR: 103660185(KIF2B) 103663645(KIF2A) 103667044(KIF24) 103670788(KIF2C)
UAH: 113254762(KIF2C) 113255297(KIF2A) 113260654(KIF24) 113265191(KIF2B)
ORO: 101362426(KIF2B) 101367296(KIF24) 101384491(KIF2A) 101386285(KIF2C)
FCA: 101087183(KIF2B) 101087504(KIF2C) 101090399(KIF24) 101099932(KIF2A)
PTG: 102960515(KIF2A) 102961176(KIF2C) 102968631(KIF24) 102970053(KIF2B)
PPAD: 109246380(KIF2A) 109247255(KIF2B) 109252026(KIF24) 109254816(KIF2C)
AJU: 106970232(KIF2C) 106975865(KIF24) 106976387(KIF2A) 106989976(KIF2B)
BTA: 513392(KIF24) 533161(KIF2C) 538921(KIF2B) 768014(KIF2A)
BOM: 102272172(KIF2B) 102272274(KIF2C) 102282759(KIF24) 102287160(KIF2A)
BIU: 109556380(KIF2C) 109563180(KIF24) 109573555(KIF2B) 109574850(KIF2A)
BBUB: 102400758(KIF2A) 102404674(KIF2B) 102410918(KIF2C) 102412063(KIF24)
CHX: 102168909(KIF24) 102179513(KIF2B) 102180081(KIF2A) 102188823(KIF2C)
OAS: 101107307(KIF2A) 101117203(KIF2C) 101117942(KIF2B) 101123527(KIF24)
SSC: 100516205(KIF2C) 100520975(KIF2B) 100522820(KIF24) 100625826(KIF2A)
CFR: 102506754(KIF2A) 102512978(KIF2C) 102516312(KIF2B) 102520758(KIF24)
CDK: 105084734(KIF2A) 105085586(KIF24) 105090887(KIF2C) 105097879(KIF2B)
BACU: 102997201(KIF2A) 103005159(KIF24) 103015569(KIF2B) 103019318(KIF2C)
LVE: 103069802(KIF2C) 103073287(KIF2A) 103079931(KIF24)
OOR: 101274121(KIF2A) 101282800(KIF2C) 101287812(KIF2B) 101288917(KIF24)
DLE: 111163095(KIF24) 111163721(KIF2B) 111175414(KIF2C) 111186306(KIF2A)
PCAD: 102978957(KIF2A) 102988939(KIF24) 102989562(KIF2C) 102994123(KIF2B)
ECB: 100050982(KIF2A) 100052754(KIF2C) 100068535(KIF24) 100070445(KIF2B)
EPZ: 103548294(KIF2C) 103552894(KIF2B) 103558155(KIF24) 103564712(KIF2A)
EAI: 106822738(KIF2C) 106826567(KIF2B) 106841392(KIF24) 106846770(KIF2A)
MYB: 102249344(KIF2B) 102254543(KIF2C) 102255640(KIF2A) 102260260(KIF24)
MYD: 102754694(KIF24) 102760536(KIF2A) 102770589(KIF2C) 102771483(KIF2B)
MNA: 107526326(KIF2A) 107526707(KIF2C) 107529820(KIF2B) 107544918(KIF24)
HAI: 109371791(KIF24) 109383360(KIF2C) 109392348(KIF2B) 109392873(KIF2A)
DRO: 112304570(KIF24) 112314572(KIF2C) 112316533(KIF2B) 112320980(KIF2A)
PALE: 102879887(KIF2A) 102885995(KIF2C) 102897153(KIF2B) 102897361(KIF24)
RAY: 107499391(KIF2C) 107502794(KIF24) 107506362(KIF2A) 107515881(KIF2B)
MJV: 108387710(KIF2A) 108389961(KIF2C) 108395377(KIF24) 108402367(KIF2B)
LAV: 100658559(KIF2A) 100659077(KIF2C) 100664101(KIF2B) 100675082(KIF24)
MDO: 100014033(KIF2C) 100015249(KIF2B) 100032333(KIF2A) 554240(KIF24)
SHR: 100917430(KIF2C) 100919567(KIF2A) 100925790(KIF2B) 100926546(KIF24)
PCW: 110194578(KIF24) 110209261(KIF2C) 110212034(KIF2B) 110222295(KIF2A)
OAA: 100074686(KIF2A) 100076663(KIF2C) 100084900(KIF24) 100682206(KIF2B)
GGA: 417390(KIF2B) 424583(KIF2C) 427156(KIF2A) 427398(KIF24)
MGP: 100538708(KIF2A) 100545375(KIF2C) 100549385(KIF2B) 104917198(KIF24)
CJO: 107305734(KIF24) 107306031(KIF2A) 107317553(KIF2C) 107322297(KIF2B)
NMEL: 110389289(KIF24) 110389387(KIF2A) 110402915(KIF2C) 110407253(KIF2B)
APLA: 101789665(KIF24) 101789767(KIF2B) 101795197(KIF2A) 101797743 101798219(KIF2C)
ACYG: 106033063(KIF2C) 106034645(KIF2B) 106035604(KIF2A) 106045170(KIF24)
TGU: 100230915(KIF24) 100231498(KIF2A) 100232764(KIF2C) 116806870
LSR: 110467645(KIF2C) 110472572(KIF2A) 110484184(KIF24)
SCAN: 103814972(KIF2C) 103820684(KIF24) 103823127(KIF2A) 103826099
GFR: 102034889(KIF2A) 102036814(KIF2C) 102037220(KIF24) 102042834
FAB: 101812537(KIF2A) 101813994(KIF24) 101819687(KIF2C)
PHI: 102107769(KIF2C) 102108359(KIF2A) 102108539(KIF24)
PMAJ: 107208458(KIF2C) 107216133(KIF2A) 107216304(KIF24)
CCAE: 111922466(KIF2C) 111941029(KIF24) 111941429(KIF2A)
CCW: 104686546(KIF24) 104686691(KIF2A) 104695541(KIF2C)
ETL: 114057200(KIF2A) 114060145(KIF24) 114061868(KIF2C) 114066348
FPG: 101912995(KIF2B) 101915514(KIF2C) 101921350(KIF2A) 101924351(KIF24)
FCH: 102049463(KIF2C) 102057293(KIF24) 102058384(KIF2B) 102058811(KIF2A)
CLV: 102090730(KIF24) 102090890(KIF2C) 102095378(KIF2A)
EGZ: 104126266(KIF2C) 104132514(KIF2A) 104133870(KIF24)
NNI: 104011909(KIF2A) 104015421(KIF2C) 104017971(KIF24) 104020651
ACUN: 113482923(KIF2C) 113486949(KIF2B) 113489661(KIF24) 113489719(KIF2A)
PADL: 103914206(KIF2A) 103918304(KIF2C) 103923256(KIF24)
AAM: 106493105(KIF2B) 106493693(KIF24) 106500311(KIF2C)
ASN: 102375830(KIF2C) 102380595(KIF24) 102382796(KIF2B) 102385355(KIF2A)
AMJ: 102558275(KIF24) 102560383(KIF2C) 106736735(KIF2A)
PSS: 102448814(KIF24) 102450601(KIF2C) 102455355(KIF2A)
CPIC: 101933540(KIF2C) 101941689(KIF2A) 101952059(KIF24)
ACS: 100551858(kif2a) 100558145(kif2c) 100564938(kif24)
PVT: 110073742(KIF2C) 110073933(KIF2A) 110080493(KIF24)
PBI: 103048894 103052108(KIF2A) 103056659(KIF24)
PMUR: 107283433(KIF2C) 107289919(KIF2A) 107298976(KIF24)
TSR: 106545237(KIF2C) 106552899(KIF24) 106555278(KIF2A)
PMUA: 114592820(KIF2B) 114599100(KIF2C) 114606252(KIF2A) 114606348(KIF24)
XLA: 108714276(kif2c.L) 108718774 379622(kif2a.L) 380006(kif2c.S) 444122(kif2a.S)
XTR: 100379688(kif2a) 101731767(kif24) 448620(kif2c)
NPR: 108797450(KIF24) 108799178(KIF2A) 108801433(KIF2C)
DRE: 100136875(kif2c) 100333835 447926(zgc:103670)
PRET: 103470246 103470415(kif2a) 103473261 103479623(kif2c)
ALIM: 106517527(kif2a) 106523788 106531227 106534851(kif2c)
CSEM: 103389980 103396046(kif2c) 103398287(kif2a) 103398383
PKI: 111836955 111839160(kif2a)
LCM: 102345107 102355962(KIF2C) 102358299(KIF2A) 102364088(KIF24)
CMK: 103177800(kif2a) 103180985(kif24) 103182748(kif2c)
CIN: 100178068
APLC: 110987213
DME: Dmel_CG12192(Klp59D) Dmel_CG1453(Klp10A) Dmel_CG3219(Klp59C)
DSE: 6615661
DSI: Dsimw501_GD11742(Dsim_GD11742) Dsimw501_GD16001(Dsim_GD16001) Dsimw501_GD25079(Dsim_GD25079)
LCQ: 111685161
AAG: 5564400
AME: 409727
BIM: 100744100
BTER: 100648161
CCAL: 108626759
OBB: 114878729
SOC: 105202395
MPHA: 105828305
AEC: 105144866
ACEP: 105620334
PBAR: 105425828
VEM: 105564489
HST: 105190638
DQU: 106749468
CFO: 105257655
LHU: 105679811
PGC: 109858043
OBO: 105275881
PCF: 106784379
NVI: 103315959
CSOL: 105366956
MDL: 103568292
TCA: 103313266 657981(kinesin-13C) 660770(kinesin-13B)
BMOR: 100144601(MCAK)
BMAN: 114250697
PMAC: 106716077
PRAP: 110993653
HAW: 110379319
TNL: 113502178
PXY: 105394101
DNX: 107163178
AGS: 114131929
RMD: 113553880
BTAB: 109034136
CLEC: 106673343
ZNE: 110836421
FCD: 110853474
PVM: 113810125
TUT: 107367663
CSCU: 111634326
CEL: CELE_K11D9.1(klp-7)
CBR: CBG18307(Cbr-klp-7)
BMY: Bm1_42920
TSP: Tsp_05539
SHX: MS3_02471
DGT: 114540509
HMG: 101234502
AQU: 100636456
ATH: AT3G16060 AT3G16630(KINESIN-13A)
LJA: Lj0g3v0211939.1(Lj0g3v0211939.1) Lj0g3v0344519.1(Lj0g3v0344519.1) Lj1g3v4129300.1(Lj1g3v4129300.1) Lj3g3v0234070.1(Lj3g3v0234070.1) Lj6g3v1449690.1(Lj6g3v1449690.1) Lj6g3v1449690.2(Lj6g3v1449690.2)
DOSA: Os01t0625200-01(Os01g0625200) Os05t0154700-01(Os05g0154700)
ATS: 109733779(LOC109733779) 109738457(LOC109738457) 109766523(LOC109766523)
ZMA: 100280257(gpm176) 100302578 100382371(cl34021_1(372)) 103635484
APRO: F751_5522
MAW: MAC_07351
ABE: ARB_05244
TVE: TRV_02284
DDI: DDB_G0267404(kif6)
DFA: DFA_01423(kif6)
PCB: PCHAS_146060(PC000147.04.0)
TAN: TA14570
TPV: TP02_0685
BBO: BBOV_II007750(18.m06642)
CPV: cgd8_3300
SMIN: v1.2.010184.t1(symbB.v1.2.010184.t1) v1.2.018573.t1(symbB.v1.2.018573.t1) v1.2.028123.t1(symbB.v1.2.028123.t1)
PTI: PHATRDRAFT_11198(Pt-KIF9) PHATRDRAFT_23314(KRP2) PHATRDRAFT_9158(pT-KIF12)
 » show all
Reference
  Authors
Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, Fan JB, Abraham RT, Jiang W
  Title
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.
  Journal
Mol Biol Cell 16:3187-99 (2005)
DOI:10.1091/mbc.E05-02-0167
  Sequence
[hsa:3796]
Reference
  Authors
Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA
  Title
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.
  Journal
Mol Biol Cell 18:2970-9 (2007)
DOI:10.1091/mbc.E07-02-0110
  Sequence
[hsa:3796 84643]
Reference
PMID:9177777
  Authors
Debernardi S, Fontanella E, De Gregorio L, Pierotti MA, Delia D
  Title
Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique.
  Journal
Genomics 42:67-73 (1997)
DOI:10.1006/geno.1997.4720
  Sequence
[hsa:3796]
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