Entry |
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Name |
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Definition |
DNA damage-binding protein 1
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Pathway |
ko04120 | Ubiquitin mediated proteolysis |
ko05170 | Human immunodeficiency virus 1 infection |
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Disease |
H00403 | Disorders of nucleotide excision repair |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
K10610 DDB1; DNA damage-binding protein 1
09124 Replication and repair
03420 Nucleotide excision repair
K10610 DDB1; DNA damage-binding protein 1
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
K10610 DDB1; DNA damage-binding protein 1
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
K10610 DDB1; DNA damage-binding protein 1
05161 Hepatitis B
K10610 DDB1; DNA damage-binding protein 1
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system
K10610 DDB1; DNA damage-binding protein 1
03400 DNA repair and recombination proteins
K10610 DDB1; DNA damage-binding protein 1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
Cul4 complex
Adoptor protein
K10610 DDB1; DNA damage-binding protein 1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
GGR (global genome repair) factors
Cul4-DDB2 complex
K10610 DDB1; DNA damage-binding protein 1
TCR (transcription coupled repair) factors
Cul4-CSA complex
K10610 DDB1; DNA damage-binding protein 1
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Genes |
» show all
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Reference |
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Authors |
Wang H, Zhai L, Xu J, Joo HY, Jackson S, Erdjument-Bromage H, Tempst P, Xiong Y, Zhang Y |
Title |
Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. |
Journal |
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Sequence |
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Reference |
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Authors |
Lovejoy CA, Lock K, Yenamandra A, Cortez D |
Title |
DDB1 maintains genome integrity through regulation of Cdt1. |
Journal |
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Sequence |
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Reference |
|
Authors |
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H |
Title |
CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. |
Journal |
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Sequence |
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Reference |
|
Authors |
Dualan R, Brody T, Keeney S, Nichols AF, Admon A, Linn S |
Title |
Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein. |
Journal |
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Sequence |
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LinkDB |
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