KEGG   ORTHOLOGY: K10628Help
Entry
K10628                      KO                                     

Name
RAG1
Definition
V(D)J recombination-activating protein 1 [EC:2.3.2.27]
Pathway
ko04068  FoxO signaling pathway
ko05340  Primary immunodeficiency
Disease
H00092  T-B-Severe combined immunodeficiency
H00093  Combined immunodeficiency
H01244  T+B+Severe combined immunodeficiencies (SCIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K10628  RAG1; V(D)J recombination-activating protein 1
 09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    K10628  RAG1; V(D)J recombination-activating protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10628  RAG1; V(D)J recombination-activating protein 1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10628  RAG1; V(D)J recombination-activating protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K10628  RAG1; V(D)J recombination-activating protein 1
BRITE hierarchy
Genes
HSA: 5896(RAG1)
PTR: 466489(RAG1)
PPS: 100981734(RAG1)
GGO: 101149904(RAG1)
PON: 100447109(RAG1)
NLE: 100595879(RAG1)
MCC: 697322(RAG1)
MCF: 102127914(RAG1)
CSAB: 103237538(RAG1)
RRO: 104658365(RAG1)
RBB: 108535562(RAG1)
CJC: 100395720(RAG1)
SBQ: 101033618(RAG1)
MMU: 19373(Rag1)
MCAL: 110312570(Rag1)
MPAH: 110319308(Rag1)
RNO: 84600(Rag1)
MUN: 110557494(Rag1)
CGE: 100754292(Rag1)
NGI: 103749514(Rag1)
HGL: 101724556(Rag1)
CCAN: 109693568(Rag1)
OCU: 100328950(RAG1)
TUP: 102483075(RAG1)
CFA: 483420(RAG1)
VVP: 112930593(RAG1)
AML: 100483463(RAG1)
UMR: 103659304(RAG1)
UAH: 113264892(RAG1)
ORO: 101362361(RAG1)
FCA: 101096264(RAG1)
PTG: 102960431(RAG1)
AJU: 106976928(RAG1)
BTA: 506302(RAG1)
BOM: 102286166(RAG1)
BIU: 109569432(RAG1)
BBUB: 102399255(RAG1)
PHD: 102318637(RAG1)
CHX: 102173108(RAG1)
OAS: 101107384(RAG1)
SSC: 397506(RAG1)
CFR: 102519940(RAG1)
CDK: 105106824(RAG1)
BACU: 103019951(RAG1)
LVE: 103087418(RAG1)
OOR: 101277792(RAG1)
DLE: 111179771(RAG1)
ECB: 100049810(RAG1)
EPZ: 103560235(RAG1)
EAI: 106837479(RAG1)
MYB: 102251239(RAG1)
MYD: 102765656(RAG1)
MNA: 107531933(RAG1)
HAI: 109381116(RAG1)
RSS: 109450796(RAG1)
DRO: 112303162(RAG1)
PALE: 102886891(RAG1)
LAV: 100658301(RAG1)
TMU: 101345589
MDO: 100011241(RAG1)
SHR: 100922588(RAG1)
PCW: 110192650(RAG1)
OAA: 100077097(RAG1)
GGA: 423164(RAG1)
MGP: 100542632(RAG1)
CJO: 107314674(RAG1)
APLA: 101802725(RAG1)
ACYG: 106044339(RAG1)
TGU: 100224875(RAG1)
LSR: 110484459(RAG1)
SCAN: 103826722(RAG1)
GFR: 102041505(RAG1)
FAB: 101817279(RAG1)
PHI: 102105364(RAG1)
PMAJ: 107205242(RAG1)
CCAE: 111930104(RAG1)
CCW: 104694035(RAG1)
ETL: 114056747(RAG1)
FPG: 101912181(RAG1)
FCH: 102058214(RAG1)
CLV: 102084079(RAG1)
EGZ: 104134047(RAG1)
NNI: 104009614(RAG1)
ACUN: 113481163(RAG1)
AAM: 106498195(RAG1)
ASN: 102382683(RAG1)
AMJ: 102566094(RAG1)
PSS: 102463645(RAG1)
CMY: 102938739(RAG1)
CPIC: 101945962(RAG1)
ACS: 100561999(rag1)
PVT: 110090247(RAG1)
PBI: 103053491(RAG1)
PMUR: 107293336(RAG1)
GJA: 107114927(RAG1)
XLA: 100337558(rag1.L) 100337559(rag1b)
XTR: 100145555(rag1)
NPR: 108787814(RAG1)
DRE: 30663(rag1)
SGH: 107564618 107581862(rag1)
CCAR: 109051085(rag1)
IPU: 100304618(rag1)
PHYP: 113529514(rag1)
AMEX: 103044739(rag1)
EEE: 113589160(rag1)
TRU: 101070902(rag1)
LCO: 104925262(rag1)
NCC: 104941239(rag1)
MZE: 101481579(rag1)
OLA: 101159098(rag1)
XMA: 102217349(rag1)
XCO: 114151760(rag1)
PRET: 103466123(rag1)
NFU: 107388984(rag1)
KMR: 108239995(rag1)
CSEM: 103380530(rag1)
LCF: 108875106(rag1)
SDU: 111228675(rag1)
HCQ: 109530307(rag1)
BPEC: 110165948(rag1)
MALB: 109968741(rag1)
SASA: 106561304(rag1)
OTW: 112218685(rag1)
SALP: 111962443(rag1)
ELS: 105018380(rag1)
SFM: 108942182(rag1)
PKI: 111859427(rag1)
LCM: 102354195(RAG1)
CMK: 103175094(rag1)
SPU: 588498(Rag1L)
PDAM: 113681585
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grazini U, Zanardi F, Citterio E, Casola S, Goding CR, McBlane F
  Title
The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining.
  Journal
Mol Cell 37:282-93 (2010)
DOI:10.1016/j.molcel.2009.12.035
  Sequence
[mmu:19373]
LinkDB All DBs

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