KEGG   ORTHOLOGY: K11224
Entry
K11224                      KO                                     
Symbol
STAT5B
Name
signal transducer and activator of transcription 5B
Pathway
map04012  ErbB signaling pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05207  Chemical carcinogenesis - receptor activation
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05223  Non-small cell lung cancer
Disease
H00931  Growth hormone insensitivity with immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04630 JAK-STAT signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04659 Th17 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04062 Chemokine signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04935 Growth hormone synthesis, secretion and action
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05207 Chemical carcinogenesis - receptor activation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05203 Viral carcinogenesis
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05220 Chronic myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05223 Non-small cell lung cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05161 Hepatitis B
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05162 Measles
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11224  STAT5B; signal transducer and activator of transcription 5B
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11224  STAT5B; signal transducer and activator of transcription 5B
Genes
HSA: 6777(STAT5B)
PTR: 454679(STAT5B)
PPS: 100989105
GGO: 101128930
PON: 100462537(STAT5B)
NLE: 100602489
MCC: 709760(STAT5B)
MCF: 102127060
CSAB: 103243413(STAT5B)
CATY: 105579668(STAT5B)
PANU: 101000002(STAT5B)
TGE: 112610116(STAT5B)
RRO: 104680321
RBB: 108518352
TFN: 117066965
PTEH: 111537374(STAT5B)
CJC: 100388552(STAT5B)
SBQ: 101043203(STAT5B)
CSYR: 103276756
MMUR: 105859420(STAT5B)
LCAT: 123620957(STAT5B)
OGA: 100955743
MMU: 20851(Stat5b)
MCAL: 110306026(Stat5b)
MPAH: 110331105(Stat5b)
RNO: 25126(Stat5b)
MCOC: 116078734(Stat5b)
MUN: 110550889
CGE: 100750571
MAUA: 101835654(Stat5b)
PLEU: 114682785
MORG: 121442319(Stat5b)
AAMP: 119811038
NGI: 103735893(Stat5b)
HGL: 101722721(Stat5b)
CPOC: 100716532(Stat5b)
CCAN: 109692057
DORD: 106002556(Stat5b)
DSP: 122100261
NCAR: 124979870
OCU: 100348267(STAT5B)
OPI: 101518842
TUP: 102492323(STAT5B)
CFA: 490969(STAT5B)
VVP: 112910740(STAT5B)
VLG: 121472926(STAT5B)
AML: 100479246
UMR: 103672570(STAT5B)
UAH: 113265424
UAR: 123781849(STAT5B)
ELK: 111151253
LLV: 125087045
MPUF: 101692423(STAT5B)
ORO: 101372217(STAT5B)
EJU: 114201399(STAT5B)
ZCA: 113939349(STAT5B)
MLX: 118024913(STAT5B)
FCA: 101090663(STAT5B)
PYU: 121045021(STAT5B)
PBG: 122485599(STAT5B)
PTG: 102972489(STAT5B)
PPAD: 109258541
AJU: 106972565
HHV: 120248396(STAT5B)
BTA: 282376(STAT5B)
BOM: 102283211(STAT5B)
BIU: 109573773(STAT5B)
BBUB: 102400858
CHX: 102176415(STAT5B)
OAS: 101122961
ODA: 120867075
CCAD: 122441627
SSC: 397340(STAT5B)
CFR: 102511001(STAT5B)
CBAI: 105080118(STAT5B)
CDK: 105090456
VPC: 102538126
LVE: 103082258(STAT5B)
OOR: 101280265(STAT5B)
DLE: 111166483
PCAD: 102994339(STAT5B)
PSIU: 116745059(STAT5B)
ECB: 100052954
EPZ: 103550391
EAI: 106826362(STAT5B)
MYB: 102241062(STAT5B)
MMYO: 118671504
MLF: 102424720
MNA: 107528845
PKL: 118726604
DRO: 112298560(STAT5B)
SHON: 118977990
AJM: 119037510
PDIC: 114502991(STAT5B)
PHAS: 123816875(STAT5B)
MMF: 118634401(STAT5B)
RFQ: 117014073(STAT5B)
PALE: 102884882
PGIG: 120611100
PVP: 105306336
RAY: 107513822(STAT5B)
MJV: 108388330
TOD: 119232882(STAT5B)
SARA: 101552185(STAT5B)
LAV: 100669299(STAT5B)
TMU: 101354148
DNM: 101419007(STAT5B)
MDO: 100011470(STAT5B)
GAS: 123245349
SHR: 100920307(STAT5B)
PCW: 110198412
OAA: 100092915(STAT5B)
GGA: 395556(STAT5B)
PCOC: 116233608
MGP: 100546986
CJO: 107325190
NMEL: 110388528(STAT5B)
APLA: 101790203
ACYG: 106047991
AFUL: 116498619
TGU: 100222731
LSR: 110471843
SCAN: 103821589
PMOA: 120496657
OTC: 121347621
PRUF: 121351183
GFR: 102036670(STAT5B)
FAB: 101808879(STAT5B)
PHI: 102101483(STAT5B)
PMAJ: 107215121
CCAE: 111939998
CCW: 104697815
ETL: 114063604
ZAB: 102066095
FPG: 101918263(STAT5B)
FCH: 102053699
CLV: 102098622
EGZ: 104135093
NNI: 104009926
TALA: 116960729
ACHC: 115344699
AROW: 112968721
NPD: 112951852
ASN: 102380420
AMJ: 102575674(STAT5B)
CPOO: 109320364
GGN: 109289127
CPIC: 101932204
TST: 117870579
CABI: 116820372
ACS: 100566752(stat5b)
PVT: 110074911
SUND: 121933099
PBI: 103049078
TSR: 106541154
PGUT: 117664595
VKO: 123030656
PMUA: 114583662
ZVI: 118094191
GJA: 107111494
STOW: 125444644
XLA: 399176(stat5b.L) 414637(stat5b.S)
XTR: 100495240(stat5b)
NPR: 108788932
RTEM: 120918206
BBUF: 121005428
BGAR: 122941072
DRE: 369197(stat5a) 445474(stat5b)
PPRM: 120488720(stat5b) 120489715(stat5a)
MAMB: 125255293(stat5b) 125279545(stat5a)
IPU: 108273804(stat5b) 108279147(stat5a)
SMEO: 124388956(stat5b) 124396761(stat5a)
TFD: 113652201(stat5a) 113662164(stat5b)
TRU: 101071345
ELY: 117247445 117268498(stat5a)
PLEP: 121956090(stat5a) 121958483
SLUC: 116059636(stat5a) 116067487
ECRA: 117936750 117958410(stat5a)
GAT: 120819248 120828238(stat5a)
PPUG: 119212799 119220165(stat5a)
MSAM: 119892306(stat5a) 119916364
CUD: 121528063 121529468(stat5a)
ALAT: 119009634 119013365(stat5a)
OAU: 116312472(stat5a) 116320031
OML: 112146942(stat5a) 112162336
GAF: 122821445(stat5a) 122823242
CTUL: 119778879(stat5a) 119796116
KMR: 108243804(stat5a) 108245177
NWH: 119421910(stat5a) 119424214
MCEP: 124997980(stat5a) 125022426
SSEN: 122759289 122785610(stat5a)
HHIP: 117752427 117766855(stat5a)
HSP: 118100442 118122878(stat5a)
XGL: 120785048(stat5a) 120794630
BSPL: 114845404 114860995(stat5a)
PKI: 111856018
AANG: 118220791(stat5a)
LOC: 102697320(stat5b)
ARUT: 117433413 117435028(stat5a)
LCM: 102348150(STAT5B) 102350580(STAT6)
CMK: 103189177(stat5a)
CIN: 778770(stat-b) 778907
SPU: 576433
SKO: 100313741
DME: Dmel_CG4257(Stat92E)
DER: 6553695
DSE: 6619260
DSI: Dsimw501_GD20060(Dsim_GD20060)
DSR: 110188679
DPE: 6588035
DMN: 108155914
DGR: 6569826
DAZ: 108615391
DNV: 108653502
DVI: 6629898
MDE: 101895093
SCAC: 106096271
LCQ: 111679071
LSQ: 119609107
HIS: 119652245
AGA: AgaP_AGAP000099(STAT2) AgaP_AGAP010423(STAT_ANOGA)
AAG: 5572256
AALB: 109422192
AME: 413742
ACER: 108001157
ALAB: 122712845
BIM: 100743540
BBIF: 117209933
BVK: 117230840
BVAN: 117166453
BTER: 100647789
BPYO: 122576024
CCAL: 108630675
OBB: 114873069
MGEN: 117219619
NMEA: 116431444
CGIG: 122394871
SOC: 105193817
MPHA: 105832515
AEC: 105148183
ACEP: 105624336
PBAR: 105433521
VEM: 105563878
HST: 105184844
DQU: 106749703
CFO: 105254529
FEX: 115240525
LHU: 105672556
PGC: 109854643
OBO: 105281780
PCF: 106789625
PFUC: 122513482
VPS: 122636943
NVI: 100121885
CSOL: 105361759
TPRE: 106651566
MDL: 103580774
CGLO: 123263507
FAS: 105266810
DAM: 107040670
AGIF: 122848525
CCIN: 107275017
TCA: 657965(Stat)
DPA: 109540291
SOY: 115875164
ATD: 109594135
CSET: 123312582
AGB: 108914584
LDC: 111509439
NVL: 108559383
APLN: 108732879
PPYR: 116170388
OTU: 111415033
BMOR: 100302627(Stat)
BMAN: 114244414
MSEX: 115451759
BANY: 112051221
PPOT: 106107473
PXU: 106126003
PRAP: 110992522
ZCE: 119838494
HAW: 110381656
TNL: 113509063
SLIU: 111359030
OFU: 114354585
API: 100161101
BTAB: 109041216
DCI: 103509325
HHAL: 106683428
NLU: 111049728
FOC: 113201738
ZNE: 110830516
CSEC: 111869855
PVM: 113830023
PJA: 122265890
PCHN: 125040688
PCLA: 123758708
PTRU: 123508992
PPOI: 119111901
DSV: 119456101
RSAN: 119393749
RMP: 119171954
CSCU: 111623415
SDM: 118189820
CEL: CELE_Y51H4A.17(sta-1)
CBR: CBG_13675(Cbr-sta-1)
BMY: BM_BM6729(Bma-sta-1)
TSP: Tsp_04456
GAE: 121370464
HRF: 124139325
OSN: 115220884
ADF: 107338381
AMIL: 114964117
SPIS: 111328363
XEN: 124437962
HMG: 100206878
AQU: 100641588
 » show all
Reference
PMID:8732682
  Authors
Silva CM, Lu H, Day RN
  Title
Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
  Journal
Mol Endocrinol 10:508-18 (1996)
DOI:10.1210/mend.10.5.8732682
  Sequence
[hsa:6777]
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