KEGG   ORTHOLOGY: K11448Help
Entry
K11448                      KO                                     

Name
KDM6B, JMJD3
Definition
lysine-specific demethylase 6B [EC:1.14.11.68]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11448  KDM6B, JMJD3; lysine-specific demethylase 6B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     K11448  KDM6B, JMJD3; lysine-specific demethylase 6B
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    K11448  KDM6B, JMJD3; lysine-specific demethylase 6B
BRITE hierarchy
Other DBs
GO: 0071558
Genes
HSA: 23135(KDM6B)
PTR: 468438(KDM6B)
PPS: 100971965(KDM6B)
GGO: 101146851(KDM6B)
PON: 100440779(KDM6B)
NLE: 100581756(KDM6B)
MCC: 716348(KDM6B)
MCF: 102138681(KDM6B)
CSAB: 103242325(KDM6B)
RRO: 104661704(KDM6B)
RBB: 108514285(KDM6B)
CJC: 100414637(KDM6B)
SBQ: 101031578(KDM6B)
MMU: 216850(Kdm6b)
MCAL: 110304445(Kdm6b)
MPAH: 110331384(Kdm6b)
RNO: 363630(Kdm6b)
MUN: 110555144(Kdm6b)
CGE: 100756212(Kdm6b)
NGI: 103752113(Kdm6b)
HGL: 101703654(Kdm6b)
CCAN: 109693893(Kdm6b)
OCU: 100343083(KDM6B)
TUP: 102482383(KDM6B)
CFA: 489481(KDM6B)
VVP: 112924857(KDM6B)
AML: 100477084(KDM6B)
UMR: 103660480(KDM6B)
UAH: 113271139(KDM6B)
ORO: 101385984(KDM6B)
FCA: 101100010(KDM6B)
PPAD: 109246086(KDM6B)
AJU: 106972505(KDM6B)
BTA: 100140276(KDM6B)
BOM: 102273800(KDM6B)
BIU: 109573750(KDM6B)
BBUB: 102395023(KDM6B)
CHX: 102168575(KDM6B)
OAS: 101119656(KDM6B)
SSC: 100512495(KDM6B)
CFR: 102523561(KDM6B)
CDK: 105103070(KDM6B)
BACU: 103016921(KDM6B)
LVE: 103083949(KDM6B)
OOR: 101284645(KDM6B)
DLE: 111185695(KDM6B)
PCAD: 102976704(KDM6B)
ECB: 100073033(KDM6B)
EAI: 106844144(KDM6B)
MYB: 102242922(KDM6B)
MYD: 102775429(KDM6B)
MNA: 107544494(KDM6B)
HAI: 109395116(KDM6B)
DRO: 112308749(KDM6B)
PALE: 102891492(KDM6B)
RAY: 107515683(KDM6B)
MJV: 108383384(KDM6B)
LAV: 100669880(KDM6B)
TMU: 101351058
SHR: 100914132(KDM6B)
PCW: 110194281(KDM6B)
OAA: 103167751(KDM6B)
ACYG: 106049694
LSR: 110481217(KDM6B)
FAB: 101811628(KDM6B)
PHI: 102100209(KDM6B)
FPG: 101916863(KDM6B)
ASN: 102378019(KDM6B)
AMJ: 102565918(KDM6B)
PSS: 102452800(KDM6B)
CMY: 102947171(KDM6B)
CPIC: 101935571(KDM6B)
ACS: 100561474(kdm6b)
PVT: 110087745(KDM6B)
PBI: 103065886(KDM6B)
PMUR: 107299463(KDM6B)
TSR: 106548216 106552123(KDM6B)
PMUA: 114582422(KDM6B)
GJA: 107119809(KDM6B)
XLA: 108703539(kdm6b.S) 108711772(kdm6b.L)
XTR: 779446(kdm6b)
NPR: 108794738(KDM6B)
DRE: 556678(kdm6ba) 563644(kdm6bb)
IPU: 108267706(kdm6b) 108277160
PHYP: 113524185 113540439(kdm6b)
AMEX: 103028490 103028970(kdm6b)
EEE: 113580619 113585093(kdm6b)
LCO: 104920017 104925205(kdm6b)
NCC: 104942379 104964153(kdm6b)
MZE: 101465943(kdm6b) 101474873
ONL: 100699848 100712234(kdm6b)
XCO: 114153368 114157363(kdm6b)
PRET: 103475867 103480559(kdm6b)
CVG: 107082570 107099034(kdm6b)
NFU: 107376882(kdm6b) 107386615
AOCE: 111571569(kdm6b) 111571985
CSEM: 103391115(kdm6b) 103394748
SDU: 111222373 111231320(kdm6b)
MALB: 109960405 109971923(kdm6b)
ELS: 105024598 105028179(kdm6b)
SFM: 108929716(kdm6b) 108934098
PKI: 111832775(kdm6b) 111852944
LCM: 102354908(KDM6B)
RTP: 109924747(kdm6b)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K
  Title
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.
  Journal
Nature 449:731-4 (2007)
DOI:10.1038/nature06145
  Sequence
[hsa:23135]
Reference
  Authors
De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G
  Title
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing.
  Journal
Cell 130:1083-94 (2007)
DOI:10.1016/j.cell.2007.08.019
  Sequence
[hsa:23135] [mmu:216850]
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