KEGG   ORTHOLOGY: K11828
Entry
K11828                      KO                                     

Name
DLG4, PSD95
Definition
discs large protein 4
Pathway
ko04390  Hippo signaling pathway
ko04724  Glutamatergic synapse
ko05016  Huntington disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05030  Cocaine addiction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K11828  DLG4, PSD95; discs large protein 4
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K11828  DLG4, PSD95; discs large protein 4
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K11828  DLG4, PSD95; discs large protein 4
   05022 Pathways of neurodegeneration - multiple diseases
    K11828  DLG4, PSD95; discs large protein 4
  09165 Substance dependence
   05030 Cocaine addiction
    K11828  DLG4, PSD95; discs large protein 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K11828  DLG4, PSD95; discs large protein 4
Membrane trafficking [BR:ko04131]
 SNARE
  SNARE associated proteins
   Others
    K11828  DLG4, PSD95; discs large protein 4
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    K11828  DLG4, PSD95; discs large protein 4
Genes
HSA: 1742(DLG4)
PTR: 468444(DLG4)
PPS: 100985837(DLG4)
GGO: 101145671(DLG4)
PON: 100453630(DLG4)
NLE: 100585245(DLG4)
MCC: 714273(DLG4)
MCF: 101865770(DLG4)
CSAB: 103242276(DLG4)
RRO: 104673336(DLG4)
RBB: 108514296(DLG4)
CJC: 100398576(DLG4)
SBQ: 101027754(DLG4)
MMU: 13385(Dlg4)
MCAL: 110304162(Dlg4)
MPAH: 110332219(Dlg4)
RNO: 29495(Dlg4)
MUN: 110555094(Dlg4)
CGE: 100762874(Dlg4)
NGI: 103752160(Dlg4)
HGL: 101708587(Dlg4)
CCAN: 109674497(Dlg4)
OCU: 100339587(DLG4)
TUP: 102486732(DLG4)
CFA: 489462(DLG4)
VVP: 112924816(DLG4)
AML: 100479751(DLG4)
UMR: 103660461(DLG4)
UAH: 113271106(DLG4)
ORO: 101375926(DLG4)
ELK: 111161072
FCA: 101093902(DLG4)
PTG: 102968603(DLG4)
PPAD: 109245977(DLG4)
AJU: 106972413(DLG4)
BTA: 100137840(DLG4)
BOM: 102282219(DLG4)
BIU: 109573932(DLG4)
BBUB: 102406488(DLG4)
CHX: 102187803(DLG4)
OAS: 101116743(DLG4)
SSC: 100626077(DLG4)
CFR: 102504814(DLG4)
CDK: 105103049(DLG4)
BACU: 103001428(DLG4)
LVE: 103077734(DLG4)
OOR: 101275062(DLG4)
DLE: 111185662(DLG4)
PCAD: 102974250(DLG4)
ECB: 100061544(DLG4)
EPZ: 103540298(DLG4)
EAI: 106844173(DLG4)
MYB: 102257650(DLG4)
MYD: 102773344(DLG4)
MNA: 107544252(DLG4)
HAI: 109394613(DLG4)
DRO: 112308630(DLG4)
PALE: 102889275(DLG4)
RAY: 107509512(DLG4)
MJV: 108401218(DLG4)
LAV: 100656811(DLG4)
TMU: 101360753
MDO: 100016655(DLG4)
SHR: 100930883(DLG4)
PCW: 110194304(DLG4)
OAA: 100078807(DLG4)
LSR: 110481216
GFR: 102036398
NNI: 104012563
ASN: 102377313(DLG4)
AMJ: 102560362(DLG4)
PSS: 102443619(DLG4)
CPIC: 101944806(DLG4)
ACS: 103281952
PVT: 110082313(DLG4)
PBI: 103066401(DLG4)
PMUR: 107300335(DLG4)
TSR: 106552297
PMUA: 114608043(DLG4)
GJA: 107118070(DLG4)
XTR: 779559(dlg4)
DRE: 100000823(dlg4) 405796(dlg4b)
CCAR: 109079797
PHYP: 113531412
EEE: 113586849
NCC: 104941840(dlg4)
OLA: 101159214
PRET: 103475845(dlg4)
KMR: 108248807 108250468(dlg4b)
ALIM: 106526141(dlg4)
AOCE: 111563200 111587179(dlg4)
CSEM: 103389793 103395581(dlg4)
POV: 109628693(dlg4)
SDU: 111234292(dlg4) 111239738
SLAL: 111666249(dlg4)
HCQ: 109517978(dlg4) 109518216
BPEC: 110158421(dlg4)
MALB: 109952440 109959428(dlg4)
SALP: 111963712
SFM: 108920348
PKI: 111836332 111839579(dlg4)
LCM: 102364285(DLG4)
 » show all
Reference
PMID:9286702
  Authors
Stathakis DG, Hoover KB, You Z, Bryant PJ
  Title
Human postsynaptic density-95 (PSD95): location of the gene (DLG4) and possible function in nonneural as well as in neural tissues.
  Journal
Genomics 44:71-82 (1997)
DOI:10.1006/geno.1997.4848
  Sequence
[hsa:1742]
Reference
  Authors
Kennedy MB
  Title
Signal-processing machines at the postsynaptic density.
  Journal
Science 290:750-4 (2000)
DOI:10.1126/science.290.5492.750
Reference
  Authors
Prange O, Wong TP, Gerrow K, Wang YT, El-Husseini A
  Title
A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin.
  Journal
Proc Natl Acad Sci U S A 101:13915-20 (2004)
DOI:10.1073/pnas.0405939101
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