KEGG ORTHOLOGY: K12044

ORTHOLOGY: K12044

Entry

K12044 KO

Name

TNNI3

Definition

troponin I, cardiac muscle

Pathway

ko04024

cAMP signaling pathway

ko04260

Cardiac muscle contraction

ko04261

Adrenergic signaling in cardiomyocytes

ko05410

Hypertrophic cardiomyopathy

ko05414

Dilated cardiomyopathy

ko05415

Diabetic cardiomyopathy

Disease

H00292

Hypertrophic cardiomyopathy

H00294

Dilated cardiomyopathy

H01219

Restrictive cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K12044  TNNI3; troponin I, cardiac muscle
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12044  TNNI3; troponin I, cardiac muscle
   04261 Adrenergic signaling in cardiomyocytes
    K12044  TNNI3; troponin I, cardiac muscle
09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
   05414 Dilated cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
   05415 Diabetic cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12044  TNNI3; troponin I, cardiac muscle
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Troponins
     K12044  TNNI3; troponin I, cardiac muscle

Other DBs

GO:	0030172 0031014

Genes

HSA:	7137(TNNI3)

PTR:	735514(TNNI3)

PPS:	100987819(TNNI3)

GGO:	101137001(TNNI3)

PON:	100173211(TNNI3)

NLE:	100590739(TNNI3)

MCC:	698470(TNNI3)

MCF:	102122269(TNNI3)

CSAB:

103235292(TNNI3)

RRO:	104674758(TNNI3)

RBB:	108542529(TNNI3)

CJC:	100389415(TNNI3)

SBQ:	101046410(TNNI3)

MMU:	21954(Tnni3)

MCAL:

110298605(Tnni3)

MPAH:

110336690(Tnni3)

RNO:	29248(Tnni3)

MUN:	110561052(Tnni3)

CGE:

113837253

NGI:	103744862(Tnni3)

HGL:	101711288(Tnni3)

CCAN:

109696273(Tnni3)

TUP:	102497806(TNNI3)

CFA:	403566(TNNI3)

VVP:	112909344(TNNI3)

AML:	100471638(TNNI3)

UMR:	103680268(TNNI3)

ORO:	101384802(TNNI3)

ELK:

111140065

FCA:	493744(TNNI3)

PTG:	102964327(TNNI3)

PPAD:

109259919(TNNI3)

AJU:	106980877(TNNI3)

BTA:	511094(TNNI3)

BOM:	102271644(TNNI3)

BIU:	109572857(TNNI3)

BBUB:

102413284(TNNI3)

CHX:	100860775(TNNI3)

OAS:	101121961(TNNI3)

SSC:	100049696(TNNI3)

CFR:	102512551(TNNI3)

CDK:	105098776(TNNI3)

BACU:

103008175(TNNI3)

LVE:	103083728(TNNI3)

OOR:	101276056(TNNI3)

DLE:	111181027(TNNI3)

PCAD:

102986127(TNNI3)

ECB:	100034065(TNNI3)

EPZ:	103562864(TNNI3)

EAI:	106840925(TNNI3)

MYD:	102759613(TNNI3)

MNA:	107541326(TNNI3)

HAI:	109373796(TNNI3)

DRO:	112313852(TNNI3)

PALE:

102889585(TNNI3)

RAY:	107515439(TNNI3)

MJV:	108396327(TNNI3)

TMU:

101356235

MDO:	100032908(TNNI3)

SHR:	116422945(TNNI3)

PCW:	110220013(TNNI3)

OAA:	100077614(TNNI3)

MGP:	100303672(TNNI3)

CJO:

107307234

NMEL:

110391348(TNNI3)

LSR:

PHI:

CCAE:

NNI:

ASN:	102377294(TNNI3)

AMJ:	102575200(TNNI3)

CMY:	119564848(TNNI3)

CPIC:

101942367(TNNI3)

ACS:	100564471(tnni3)

PVT:	110078530(TNNI3)

PBI:	103063845(TNNI3)

PMUR:

107282457(TNNI3) 107298483

TSR:

106538688

PMUA:

114582228(TNNI3)

GJA:	107118434(TNNI3)

XLA:	397803(tnni3.S) 494826(tnni3.L)

XTR:	496889(tnni3)

NPR:	108794936(TNNI3)

LCM:	102364336(TNNI3)

DER:

6550283

DSI:	Dsimw501_GD24482(Dsim_GD24482)

DYA:	Dyak_GE15552(Dyak_wupA)

DPO:	Dpse_GA22383(Dpse_TpnI)

DPE:

6596852

DMN:

108153251

DWI:

6648493

DGR:	Dgri_GH11970

DMO:	Dmoj_GI14711

DAZ:

108618682

DNV:	108656035 115565621

MDE:

101895885

LCQ:

111675329

AGA:	AgaP_AGAP001053

AAG:

5574015

AALB:

109427533 115253670

CQU:	CpipJ_CPIJ014296

AME:	410815(TpnI)

BIM:

BTER:

CCAL:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

PGC:

OBO:

PCF:

NVI:

MDL:	103569650 103577941

TCA:

DPA:

ATD:

NVL:

BMOR:

692734(TpnI)

BMAN:

114252543

DPL:	KGM_209334

PMAC:

PRAP:

HAW:

PXY:

API:

BTAB:

CLEC:

PHU:	Phum_PHUM503610

ZNE:	110826525 110840873

FCD:

110846018

DPX:	DAPPUDRAFT_202596

PVM:

113813611

ISC:	IscW_ISCW023443

TUT:	107363306 107364011 107365618 107369077 107370019

DPTE:

113796859 113799619

CSCU:

111640285

PTEP:

107445469

CBR:	CBG15446(Cbr-unc-27)

BMY:

Bm1_35060

LOA:	LOAG_08015

TSP:

Tsp_09119

» show all

Reference

PMID:22876777

Authors

Rani DS, Nallari P, Priyamvada S, Narasimhan C, Singh L, Thangaraj K

Title

High prevalence of Arginine to Glutamine Substitution at 98, 141 and 162 positions in Troponin I (TNNI3) associated with hypertrophic cardiomyopathy among Indians.

Journal

BMC Med Genet 13:69 (2012)
DOI:10.1186/1471-2350-13-69

Sequence

[hsa:7137]

Reference

PMID:2226790

Authors

Vallins WJ, Brand NJ, Dabhade N, Butler-Browne G, Yacoub MH, Barton PJ

Title

Molecular cloning of human cardiac troponin I using polymerase chain reaction.

Journal

FEBS Lett 270:57-61 (1990)
DOI:10.1016/0014-5793(90)81234-f

Sequence

[hsa:7137]

LinkDB

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