KEGG   ORTHOLOGY: K12185Help
Entry
K12185                      KO                                     

Name
VPS37
Definition
ESCRT-I complex subunit VPS37
Pathway
ko04144  Endocytosis
Disease
H00266  Hereditary spastic paraplegia
H01439  Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12185  VPS37; ESCRT-I complex subunit VPS37
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12185  VPS37; ESCRT-I complex subunit VPS37
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K12185  VPS37; ESCRT-I complex subunit VPS37
Membrane trafficking [BR:ko04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-I complex
    K12185  VPS37; ESCRT-I complex subunit VPS37
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12185  VPS37; ESCRT-I complex subunit VPS37
  Exosomal proteins of colorectal cancer cells
   K12185  VPS37; ESCRT-I complex subunit VPS37
BRITE hierarchy
Genes
HSA: 137492(VPS37A) 155382(VPS37D) 55048(VPS37C) 79720(VPS37B)
PTR: 451231(VPS37C) 452334(VPS37B) 472409(VPS37D) 472921(VPS37A)
PPS: 100968398(VPS37A) 100977121(VPS37D) 100985739(VPS37B) 100986950(VPS37C)
GGO: 101126819(VPS37C) 101131067(VPS37B) 101143022(VPS37A) 101144478(VPS37D)
PON: 100172801(VPS37C) 100431650(VPS37A) 100439471(VPS37D) 100443919(VPS37B)
NLE: 100581136(VPS37B) 100583556(VPS37D) 100587445(VPS37C) 100604839(VPS37A)
MCC: 694898(VPS37C) 703415(VPS37B) 710187(VPS37A) 720111(VPS37D)
MCF: 102116881(VPS37B) 102141753(VPS37A) 102142247(VPS37C) 102144748(VPS37D)
CSAB: 103215387(VPS37A) 103234543(VPS37C) 103239317(VPS37B) 103246633(VPS37D)
RRO: 104666311(VPS37B) 104671071(VPS37A) 104679398(VPS37C) 104681367(VPS37D)
RBB: 108517364(VPS37D) 108526459(VPS37A) 108528785(VPS37C) 108540920(VPS37B)
CJC: 100385623(VPS37C) 100399743(VPS37D) 100409163(VPS37B) 100415040(VPS37A)
SBQ: 101031806(VPS37D) 101041364(VPS37A) 101042286(VPS37B) 101046549(VPS37C)
MMU: 107305(Vps37c) 194309(Vps37d) 330192(Vps37b) 52348(Vps37a)
MCAL: 110285485(Vps37c) 110294325(Vps37b) 110295269(Vps37d) 110299653(Vps37a)
MPAH: 110312875(Vps37b) 110312934(Vps37d) 110323317(Vps37c) 110336173(Vps37a)
RNO: 108348178(NEWGENE_1309258) 288659(Vps37b) 290775(Vps37a) 308178(Vps37c) 687208(Vps37d)
MUN: 110548104(Vps37c) 110558050(Vps37b) 110564344(Vps37d) 110565615(Vps37a)
CGE: 100751708(Vps37a) 100755847(Vps37d) 100763936(Vps37c) 100767219(Vps37b)
NGI: 103725200(Vps37c) 103739043(Vps37b) 103743277(Vps37a) 103746268(Vps37d)
HGL: 101700435(Vps37a) 101706319(Vps37d) 101715183(Vps37b) 101715774 101721739(Vps37c)
CCAN: 109683536(Vps37b) 109687681(Vps37c) 109697638(Vps37d) 109698041(Vps37a)
OCU: 100347127(VPS37A) 100347637(VPS37B) 100356920(VPS37C)
TUP: 102478136(VPS37B) 102481437(VPS37D) 102489786(VPS37C) 102497665(VPS37A)
CFA: 475611(VPS37A) 477457(VPS37B) 483803(VPS37C) 489806(VPS37D)
VVP: 112908937(VPS37A) 112911055(VPS37C) 112933831(VPS37B) 112935738(VPS37D)
AML: 100470158(VPS37B) 100470781(VPS37D) 100473034(VPS37A) 100476764(VPS37C)
UMR: 103661259(VPS37B) 103670224(VPS37D) 103678223(VPS37C) 103681374(VPS37A)
UAH: 113246972(VPS37C) 113262159(VPS37A) 113266913(VPS37B) 113267791(VPS37D)
ORO: 101370790(VPS37D) 101371134(VPS37C) 101377268(VPS37B) 101381396(VPS37A)
FCA: 101083260(VPS37A) 101083544(VPS37C) 101090470(VPS37B) 101096626(VPS37D)
PTG: 102964612(VPS37A) 102968062(VPS37B) 102968509(VPS37D) 102970358(VPS37C)
AJU: 106967602(VPS37B) 106972638(VPS37A) 106977495(VPS37D) 106977862(VPS37C)
BTA: 513985(VPS37A) 535566(VPS37B) 539811(VPS37D) 613817(VPS37C)
BOM: 102268915(VPS37B) 102273315(VPS37D) 102276203(VPS37C) 102283343(VPS37A)
BIU: 109553419(VPS37A) 109554547(VPS37C) 109570909(VPS37B) 109578848(VPS37D)
BBUB: 102391091(VPS37A) 102396773(VPS37D) 102411653(VPS37B) 102411851(VPS37C)
PHD: 102324247(VPS37C) 102329408(VPS37A) 102334312(VPS37B) 102343312
CHX: 102170753(VPS37A) 102178006(VPS37B) 102179344(VPS37D) 102190024(VPS37C)
OAS: 101113456(VPS37D) 101120049(VPS37A) 101122144(VPS37C) 101123071(VPS37B)
SSC: 100152918(VPS37B) 100511491(VPS37C) 100524550(VPS37D)
CFR: 102506567(VPS37B) 102522705(VPS37A) 102523237(VPS37D) 102523482(VPS37C)
CDK: 105089669(VPS37D) 105094938(VPS37C) 105102366(VPS37A) 105102536(VPS37B)
BACU: 103010360(VPS37A) 103012077(VPS37B) 103014953(VPS37D) 103016031(VPS37C)
LVE: 103083097(VPS37B) 103083546(VPS37D) 103089378(VPS37C) 103089791(VPS37A)
OOR: 101270424(VPS37C) 101273394(VPS37B) 101274048(VPS37A) 101281818(VPS37D)
DLE: 111173447(VPS37A) 111182040(VPS37D) 111183899(VPS37C) 111186979(VPS37B)
ECB: 100050168(VPS37A) 100058900(VPS37B) 100059152(VPS37C) 100061734(VPS37D)
EPZ: 103545676(VPS37A) 103549893(VPS37B) 103563083(VPS37D) 103564474(VPS37C)
EAI: 106828212(VPS37A) 106837128(VPS37D) 106842223(VPS37B) 106844377(VPS37C)
MYB: 102250098(VPS37A) 102253084(VPS37C) 102255631(VPS37D) 102260734(VPS37B)
MYD: 102763117(VPS37C) 102765438(VPS37A) 102771931(VPS37B) 102774720(VPS37D)
MNA: 107526559(VPS37D) 107527646(VPS37C) 107534074(VPS37A) 107541844(VPS37B)
HAI: 109384974(VPS37D) 109390049(VPS37C) 109394580(VPS37A)
RSS: 109448543(VPS37B) 109450545(VPS37A) 109459542(VPS37C) 109459968(VPS37D)
DRO: 112306647(VPS37A) 112310633(VPS37B) 112314925(VPS37D) 112317061(VPS37C)
PALE: 102877920(VPS37D) 102887345(VPS37A) 102897750(VPS37B) 102897999(VPS37C)
LAV: 100657362(VPS37A) 100660042(VPS37C) 100663932(VPS37B) 100677296(VPS37D)
MDO: 100021722(VPS37A) 100022642(VPS37B) 100027110(VPS37C) 100029510(VPS37D)
SHR: 100914138(VPS37D) 100926429(VPS37C) 100928917(VPS37A) 100931466(VPS37B)
PCW: 110196832(VPS37B) 110200695(VPS37C) 110201234(VPS37A) 110221339(VPS37D)
OAA: 100074833(VPS37A) 100075454(VPS37B) 100084407(VPS37C) 114817915(VPS37D)
GGA: 100859879(VPS37D) 416835(VPS37B) 422732(VPS37A) 423023(VPS37C)
MGP: 100539197(VPS37C) 100541625(VPS37B) 100551152(VPS37A)
CJO: 107313731(VPS37A) 107314248(VPS37C) 107321132(VPS37B) 107322418(VPS37D)
APLA: 101793242(VPS37C) 101803366(VPS37D) 101804693(VPS37B) 101805402(VPS37A)
ACYG: 106031159(VPS37B) 106035199(VPS37A) 106041085(VPS37D) 106048302(VPS37C)
TGU: 100219087(VPS37C) 100226693(VPS37B) 100231817(VPS37A)
LSR: 110471769(VPS37B) 110473342(VPS37A) 110476627(VPS37D) 110485080(VPS37C)
SCAN: 103818176(VPS37B) 103820235(VPS37D) 103822145(VPS37C) 103826199(VPS37A)
GFR: 102037447(VPS37C) 102038672(VPS37B) 102044544(VPS37A) 106631908(VPS37D)
FAB: 101811086(VPS37D) 101814284(VPS37C) 101815870(VPS37B) 101821249(VPS37A)
PHI: 102102334(VPS37C) 102103501(VPS37D) 102110006(VPS37A) 102111207(VPS37B)
PMAJ: 107203106(VPS37A) 107206063(VPS37C) 107211715(VPS37B) 107212700(VPS37D)
CCAE: 111927992(VPS37A) 111930608(VPS37C) 111936376(VPS37B) 111937651(VPS37D)
CCW: 104684124(VPS37C) 104688712(VPS37B) 104690604(VPS37A) 104691139(VPS37D)
ETL: 114054961(VPS37B) 114063345(VPS37C) 114065453(VPS37A) 114068975(VPS37D)
FPG: 101913942(VPS37B) 101916775(VPS37A) 101917459(VPS37D) 101924307(VPS37C)
FCH: 102046358(VPS37A) 102049223(VPS37B) 102059625(VPS37C) 106631213(VPS37D)
CLV: 102083433(VPS37D) 102086951(VPS37B) 102088574(VPS37C) 102093117(VPS37A)
EGZ: 104122975 104129445(VPS37A) 104130114(VPS37B)
NNI: 104008970(VPS37C) 104012482(VPS37D) 104019592(VPS37B) 104020834(VPS37A)
ACUN: 113479156(VPS37A) 113481051(VPS37C) 113485987(VPS37B)
AAM: 106490078(VPS37A) 106495055(VPS37C) 106496106(VPS37D) 106497689(VPS37B)
ASN: 102368326(VPS37A) 102369253(VPS37B) 102381987(VPS37C) 102386774(VPS37D)
AMJ: 102563245(VPS37A) 102563584(VPS37C) 102570009(VPS37B) 102573307(VPS37D)
PSS: 102448546 102449857(VPS37A) 102456415(VPS37C) 102462796(VPS37B)
CMY: 102929697(VPS37A) 102930777(VPS37B) 102937009(VPS37C) 102938355(VPS37D)
CPIC: 101934572(VPS37C) 101939095(VPS37D) 101943951(VPS37B) 101948718(VPS37A)
ACS: 100553392(vps37c) 100553779(vps37b) 100554685(vps37a) 103282155(vps37d)
PVT: 110077891(VPS37A) 110078338(VPS37C) 110083828(VPS37B) 110084520(VPS37D)
PBI: 103050741(VPS37C) 103051646(VPS37A) 103053778(VPS37D) 103067751(VPS37B)
PMUR: 107284715(VPS37D) 107285469(VPS37B) 107292667(VPS37C) 107301769(VPS37A)
GJA: 107115914(VPS37B) 107116756(VPS37A) 107120371(VPS37C) 107125026
XLA: 100036869(vps37a.S) 108707989 108708879 379838(vps37b.L) 398913(vps37b.S) 734384(vps37a.L)
XTR: 101733750(vps37d) 394642(vps37b) 548736(vps37a)
NPR: 108787544(VPS37D) 108787742(VPS37B) 108794129(VPS37A)
DRE: 101884856(si:ch211-284f22.3) 336368(vps37a) 559483(vps37b) 566797(zgc:114173) 777738(vps37c)
IPU: 108255715(vps37b) 108260372(vps37d) 108260773(vps37a) 108262788(VPS37C)
TRU: 101063967 101064065(vps37c) 101065930(vps37b) 101070004(vps37a)
LCO: 104919187 104922255(vps37a) 104931757(vps37c) 104934809(vps37b) 109142055
OLA: 101163176(vps37b) 101170151(vps37a) 101171305 105355693
XMA: 102217034(vps37b) 102235746(vps37a) 102237643 106699940
XCO: 114144773(vps37a) 114145415 114153203 114154319(vps37b)
PRET: 103467096(vps37a) 103469548(vps37b) 103470412 103476297
NFU: 107379998 107387120(vps37d) 107390849(vps37a) 107393482(vps37b) 107395823
KMR: 108241431(vps37a) 108243620 108246440(vps37b) 108250095
SDU: 111217238 111229266(vps37a) 111230452 111231474(vps37b)
HCQ: 109517262 109519894(vps37a) 109521707 109524993(vps37b)
BPEC: 110163222(vps37b) 110166183(vps37a) 110167630
MALB: 109954781(vps37b) 109959346 109970685(vps37a) 109972578
ELS: 105006199(vps37b) 105011081(vps37d) 105015228 105021025(vps37a) 105022895(vps37c)
LCM: 102352499(VPS37A) 102353508(VPS37C) 102358448(VPS37D) 102358553(VPS37B) 102365280
CMK: 103178228(vps37a) 103180675(vps37d) 103184284(vps37b)
CIN: 100179674
DME: Dmel_CG1115(Vps37B) Dmel_CG17828(Vsp37A)
DSI: Dsimw501_GD16515(Dsim_GD16515) Dsimw501_GD19768(Dsim_GD19768)
BMOR: 101740202 732929(Vps37A)
FCD: 110852280
TUT: 107362320
DPTE: 113796421
CEL: CELE_CD4.4(vps-37)
BMY: Bm1_23015
TSP: Tsp_02011
OBI: 106872047
SHX: MS3_00636
EGL: EGR_03145
HMG: 105846896
ATH: AT2G36680 AT3G53120(VPS37-1)
THJ: 104818582
CPAP: 110822646
CIT: 102618510
TCC: 18598100
EGR: 104438802
VRA: 106758001
CAM: 101513895
LJA: Lj1g3v4691630.1(Lj1g3v4691630.1)
LANG: 109336759
FVE: 101300938
PPER: 18771047
PMUM: 103339777
PAVI: 110754225
PXB: 103939163
CSV: 101204280
CMO: 103486542
MCHA: 111014363
RCU: 8283950
JCU: 105642308
MESC: 110620105
VVI: 100264180
SIND: 105174228
DOSA: Os03t0186800-01(Os03g0186800) Os03t0572300-01(Os03g0572300)
BDI: 100826074
ATS: 109746958(LOC109746958)
SBI: 110431643
DCT: 110106304
PEQ: 110023569
CRE: CHLREDRAFT_150143(VPS37)
MNG: MNEG_0229
DDI: DDB_G0269510(vps37)
SPAR: SPRG_19299
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H
  Title
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation.
  Journal
Mol Biol Cell 15:4337-46 (2004)
DOI:10.1091/mbc.E04-03-0250
  Sequence
[hsa:137492]
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