KEGG   ORTHOLOGY: K12316Help
Entry
K12316                      KO                                     

Name
GAA
Definition
lysosomal alpha-glucosidase [EC:3.2.1.20]
Pathway
ko00052  Galactose metabolism
ko00500  Starch and sucrose metabolism
ko01100  Metabolic pathways
ko04142  Lysosome
Disease
H00069  Glycogen storage disease
H01762  Muscle glycogen storage disease
H01940  Glycogen storage disease type II
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    K12316  GAA; lysosomal alpha-glucosidase
   00500 Starch and sucrose metabolism
    K12316  GAA; lysosomal alpha-glucosidase
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K12316  GAA; lysosomal alpha-glucosidase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K12316  GAA; lysosomal alpha-glucosidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.20  alpha-glucosidase
     K12316  GAA; lysosomal alpha-glucosidase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12316  GAA; lysosomal alpha-glucosidase
BRITE hierarchy
Other DBs
RN: R00028 R00801 R00802
GO: 0004558
CAZy: GH31
Genes
HSA: 2548(GAA)
PTR: 454940(GAA)
PPS: 100970564(GAA)
GGO: 101141259(GAA)
PON: 100173365(GAA)
NLE: 100584142(GAA)
MCC: 712054(GAA)
MCF: 102141245(GAA)
CSAB: 103243690(GAA)
RRO: 104675242(GAA)
RBB: 108534154(GAA)
CJC: 100411176(GAA)
SBQ: 101042074(GAA)
MMU: 14387(Gaa)
RNO: 367562(Gaa)
CGE: 100755105(Gaa)
NGI: 103728510 103730596(Gaa)
HGL: 101718861(Gaa)
CCAN: 109684706(Gaa)
OCU: 103347590(GAA)
TUP: 102474055(GAA)
CFA: 483352(GAA)
AML: 100477070(GAA)
UMR: 103665978(GAA)
ORO: 101386503(GAA)
FCA: 101086359(GAA)
PTG: 102956310(GAA)
AJU: 106981879(GAA)
BTA: 280798(GAA)
BOM: 102273281(GAA)
BIU: 109574062(GAA)
PHD: 102318954(GAA)
CHX: 102175798(GAA)
OAS: 101121692(GAA)
SSC: 100526132(GAA)
CFR: 102510030(GAA)
CDK: 105106261(GAA)
BACU: 103019416(GAA)
LVE: 103090683(GAA)
OOR: 101288921(GAA)
ECB: 100056675(GAA)
EPZ: 103547327(GAA)
EAI: 106845535(GAA)
MYB: 102264084(GAA)
MYD: 102751832(GAA)
HAI: 109383724(GAA)
RSS: 109449420(GAA)
PALE: 102885829(GAA)
LAV: 100659459(GAA)
TMU: 101344373
MDO: 100028995 100030818(GAA)
SHR: 100914209(GAA) 100933026
OAA: 100079324(GAA) 100083052
GGA: 416462(GAAGSD) 422082(GAA)
MGP: 100547897 100548976(GAA)
CJO: 107320667(GAAI) 107321973(GAA)
APLA: 101802331(GAA)
ACYG: 106033539 106046740(GAA)
TGU: 100226089 100227842(GAA)
GFR: 102037015(GAA) 102044562
FAB: 101807850(GAA) 101820296
PHI: 102101960 102102156(GAA)
PMAJ: 107211160 107212383(GAA)
CCW: 104684825 104698238(GAA)
FPG: 101918651(GAA) 101924021
FCH: 102046260 102051071(GAA)
CLV: 102090362(GAA) 102090839
EGZ: 104128958 104130629(GAA)
ASN: 102379461 102381953(GAA)
AMJ: 102572123 102577078(GAA)
PSS: 102459990(GAA)
CMY: 102939927(GAA)
CPIC: 101932947 101945048(GAA)
ACS: 100553663 100561813(gaa)
PVT: 110084704 110090137(GAA)
PBI: 103061161 103065099(GAA)
GJA: 107118778 107119854(GAA)
XLA: 108703274
XTR: 100495955(gaa)
DRE: 100002366(gaa) 100332784(si:ch73-12o23.1)
IPU: 108258846 108260916(gaa)
AMEX: 103033787 103044115(gaa)
LCO: 104918857(gaa) 104926848
NCC: 104949822 104964793(gaa)
MZE: 101467306(gaa) 101478649
OLA: 101161640(gaa) 101169174
XMA: 102223585 102231710(gaa)
PRET: 103469228(gaa) 103481270
NFU: 107376530(gaa) 107389057
KMR: 108231909 108239235(gaa)
CSEM: 103383270 103393066(gaa)
SDU: 111216602 111227137(gaa)
HCQ: 109511032 109522721(gaa)
BPEC: 110157747 110166448(gaa)
MALB: 109952354 109969497(gaa)
OTW: 112259065(gaa)
ELS: 105013030(gaa) 105029840
SFM: 108926133 108936742(gaa)
LCM: 102355272(GAA) 102366792
CMK: 103175511(gaa) 103186597
CIN: 100187282
AME: 409365
BIM: 100745310
BTER: 100650486
SOC: 105196322
AEC: 105145111
ACEP: 105623984
PBAR: 105429028
HST: 105181904
DQU: 106748183
CFO: 105248635
LHU: 105674439
PGC: 109856932
PCF: 106792256
NVI: 100124137
MDL: 103577431
PMAC: 106718904
PRAP: 110995043
PXY: 105385777
CLEC: 106663068
CRG: 105328336
MYI: 110466933
SHX: MS3_00004
EGL: EGR_08499
EPA: 110237636
ADF: 107356546
AQU: 100634817
DDI: DDB_G0269790(gaa)
DFA: DFA_08363 DFA_12194(gaa)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH
  Title
Glycosylation-independent lysosomal targeting of acid alpha-glucosidase enhances muscle glycogen clearance in pompe mice.
  Journal
J Biol Chem 288:1428-38 (2013)
DOI:10.1074/jbc.M112.438663
Reference
  Authors
Esmer C, Becerra-Becerra R, Pena-Zepeda C, Bravo-Oro A
  Title
A novel homozygous mutation at the GAA gene in Mexicans with early-onset Pompe disease.
  Journal
Acta Myol 32:95-9 (2013)
  Sequence
[hsa:2548]
LinkDB All DBs

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