KEGG ORTHOLOGY: K12478

ORTHOLOGY: K12478

Entry

K12478                      KO

Symbol

EEA1

Name

early endosome antigen 1

Pathway

map04144

Endocytosis

map04145

Phagosome

map05152

Tuberculosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12478  EEA1; early endosome antigen 1
   04145 Phagosome
    K12478  EEA1; early endosome antigen 1
09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K12478  EEA1; early endosome antigen 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12478  EEA1; early endosome antigen 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K12478  EEA1; early endosome antigen 1
Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    K12478  EEA1; early endosome antigen 1

Genes

HSA:	8411(EEA1)

PTR:	467212(EEA1)

PPS:	100995101(EEA1)

GGO:	101139639(EEA1)

PON:	100437064(EEA1)

NLE:	100600546(EEA1)

MCC:	710381(EEA1)

MCF:	101926553(EEA1)

MTHB:

126930279

CSAB:

103238861(EEA1)

CATY:

105573395(EEA1)

PANU:

101022009(EEA1)

TGE:	112634858(EEA1)

RRO:	104678626(EEA1)

RBB:	108527188(EEA1)

TFN:	117089628(EEA1)

PTEH:

111550643(EEA1)

CANG:

105505796(EEA1)

CJC:	100402865(EEA1)

SBQ:	101049276(EEA1)

CSYR:

103249644(EEA1)

MMUR:

105877060(EEA1)

LCAT:

123639450(EEA1)

PCOQ:

105826084(EEA1)

OGA:	100944463(EEA1)

MMU:	216238(Eea1)

MCAL:

110303118(Eea1)

MPAH:

110326505(Eea1)

RNO:	314764(Eea1)

MCOC:

116076541(Eea1)

MUN:	110541395(Eea1)

CGE:

100758601

MAUA:

101837128(Eea1)

PLEU:

114701205(Eea1)

MORG:

121457873(Eea1)

MFOT:

126497447

AAMP:

119803324(Eea1)

NGI:	103726343(Eea1)

HGL:	101720751(Eea1)

CPOC:

100727802(Eea1)

CCAN:

109698460

DORD:

105989316(Eea1)

DSP:	122119113(Eea1)

NCAR:

124983015

OCU:

100345580

OPI:	101534949(EEA1)

TUP:	102476908(EEA1)

GVR:	103590599(EEA1)

CFA:	475424(EEA1)

CLUD:

112654887(EEA1)

VVP:	112914906(EEA1)

VLG:	121481098(EEA1)

AML:	100478615(EEA1)

UMR:	103660095(EEA1)

UAH:	113256168(EEA1)

UAR:	123780486(EEA1)

ELK:

111142206

LLV:

125106542

MPUF:

101680656(EEA1)

ORO:	101375167(EEA1)

EJU:	114211037(EEA1)

ZCA:	113921890(EEA1)

MLX:	117998895(EEA1)

NSU:	110577880(EEA1)

LWW:

102726284

FCA:	101088764(EEA1)

PYU:	121040628(EEA1)

PBG:	122472482(EEA1)

LRUF:

124501323

PTG:	102953114(EEA1)

PPAD:

109265321(EEA1)

AJU:	106973396(EEA1)

HHV:	120234655(EEA1)

BTA:	516259(EEA1)

BOM:

102269790

BIU:	109558337(EEA1)

BBUB:

102413456(EEA1)

BBIS:

104988402(EEA1)

CHX:	102175190(EEA1)

OAS:	101114003(EEA1)

ODA:	120858384(EEA1)

CCAD:

122427077(EEA1)

SSC:	100153403(EEA1)

CFR:	102518430(EEA1)

CBAI:

105064499(EEA1)

CDK:

105092206

VPC:	102542745(EEA1)

BACU:

103008668(EEA1)

LVE:	103068954(EEA1)

OOR:	101290453(EEA1)

DLE:	111163573(EEA1)

PCAD:

102983124(EEA1)

PSIU:

116760361(EEA1)

ECB:	100064347(EEA1)

EPZ:	103562560(EEA1)

EAI:	106831184(EEA1)

MYB:	102244755(EEA1)

MYD:	102754974(EEA1)

MMYO:

118649858(EEA1)

MLF:	102423727(EEA1)

MNA:	107538909(EEA1)

PKL:	118728546(EEA1)

HAI:	109371977(EEA1)

DRO:	112314096(EEA1)

SHON:

118999929(EEA1)

AJM:	119034756(EEA1)

PDIC:

114512675(EEA1)

PHAS:

123813482(EEA1)

MMF:	118624186(EEA1)

RFQ:	117029159(EEA1)

PALE:

102887879(EEA1)

PGIG:

120607284(EEA1)

PVP:	105293270(EEA1)

RAY:	107512267(EEA1)

MJV:	108403757(EEA1)

TOD:	119247436(EEA1)

SARA:

101555514(EEA1)

LAV:	100659213(EEA1)

TMU:

101352813

ETF:	101664307(EEA1)

DNM:	101443361(EEA1)

MDO:	100015221(EEA1)

GAS:	123250130(EEA1)

SHR:	100924053(EEA1)

PCW:	110221728(EEA1)

OAA:	100079644(EEA1)

GGA:	417896(EEA1)

PCOC:

116233507(EEA1)

MGP:	100545401(EEA1)

CJO:	107311522(EEA1)

NMEL:

110404596(EEA1)

APLA:

101805179(EEA1)

ACYG:

106036927(EEA1)

AFUL:

116502230(EEA1)

TGU:	100226301(EEA1)

LSR:	110469359(EEA1)

SCAN:

103813649(EEA1)

PMOA:

120499793(EEA1)

OTC:	121338593(EEA1)

PRUF:

121357173(EEA1)

GFR:	102036472(EEA1)

FAB:	101815452(EEA1)

PHI:	102113425(EEA1)

PMAJ:

107204598(EEA1)

CCAE:

111933595(EEA1)

CCW:	104696453(EEA1)

CBRC:

103618299(EEA1)

ETL:	114064636(EEA1)

ZAB:	102063637(EEA1)

ACHL:

103805609(EEA1)

FPG:	101915176(EEA1)

FCH:	102046731(EEA1)

CLV:	102098968(EEA1)

EGZ:	104132366(EEA1)

NNI:	104011697(EEA1)

PLET:

104619117(EEA1)

PCRI:

104031506(EEA1)

PCAO:

104046639

ACUN:

113489225(EEA1)

TALA:

104362529(EEA1)

PADL:

103914676(EEA1)

AFOR:

103903311(EEA1)

ACHC:

115336140(EEA1)

HALD:

104319039(EEA1)

HLE:	104828345(EEA1)

AGEN:

126034373

GCL:

127024342

CCRI:

104160147(EEA1)

CSTI:

104560815(EEA1)

EHS:	104507205(EEA1)

CMAC:

104479011(EEA1)

MUI:	104538360(EEA1)

FGA:	104079217(EEA1)

GSTE:

104250340(EEA1)

LDI:

104354584

MNB:

103776580

OHA:	104334506(EEA1)

NNT:	104411289(EEA1)

DPUB:

104305190(EEA1)

PGUU:

104463278(EEA1)

ACAR:

104530384(EEA1)

CPEA:

104398020(EEA1)

AVIT:

104267885

CVF:	104284330(EEA1)

CUCA:

104058436(EEA1)

TEO:

104382531

BRHI:

104491773(EEA1)

AAM:	106488181(EEA1)

AROW:

112962381(EEA1)

NPD:	112944157(EEA1)

TGT:	104565858(EEA1)

DNE:	112997189(EEA1)

SCAM:

104143875(EEA1)

ASN:	102369307(EEA1)

AMJ:	102558371(EEA1)

CPOO:

109315962(EEA1)

GGN:	109296382(EEA1)

PSS:	102454242(EEA1)

CMY:	102946277(EEA1)

CPIC:

101933024(EEA1)

TST:	117878464(EEA1)

CABI:

116816112(EEA1)

MRV:	120375837(EEA1)

ACS:	100552393(eea1)

PVT:	110091748(EEA1)

SUND:

121930856(EEA1)

PBI:	103067477(EEA1)

PMUR:

107284583(EEA1)

CTIG:

120314733(EEA1)

TSR:	106541144(EEA1)

PGUT:

117655618(EEA1)

VKO:	123036310(EEA1)

PMUA:

114605857(EEA1)

ZVI:	118090741(EEA1)

GJA:	107118648(EEA1)

STOW:

125434188(EEA1)

XLA:	108711055(eea1.L) 414564(eea1.S)

XTR:	100216061(eea1)

NPR:	108790059(EEA1)

RTEM:

120932043(EEA1)

BBUF:

120979824(EEA1)

BGAR:

122928043(EEA1)

DRE:	492695(eea1)

SRX:	107740258 107749303

SANH:

107672259 107686240

SGH:	107553935 107583815

CCAR:

109051783

CAUA:

113061522 113118282

PPRM:

120462022(eea1)

MAMB:

125254853(eea1)

IPU:	108264369 124626805

PHYP:

113534434(eea1)

SMEO:

124396122(eea1)

TFD:	113652447(eea1)

AMEX:

103021845(eea1)

EEE:	113590570(eea1)

TRU:	101064544(eea1)

TNG:	GSTEN00022803G001

LCO:	104924369(eea1)

NCC:	104954411(eea1)

CGOB:

115009466(eea1)

ELY:	117262200(eea1)

EFO:	125887134(eea1)

PLEP:

121949983(eea1)

SLUC:

116062346(eea1)

ECRA:

117949272(eea1)

ESP:	116693525(eea1)

PFLV:

114560471(eea1)

GAT:

120809852

PPUG:

119195581(eea1)

MSAM:

119894452(eea1)

CUD:	121515144(eea1)

ALAT:

119023897(eea1)

MZE:	101467934(eea1)

ONL:	100689996(eea1)

OAU:	116335577(eea1)

OLA:	101175647(eea1)

OML:	112152206(eea1)

XMA:	102234691(eea1)

XCO:	114153153(eea1)

XHE:	116733708(eea1)

PRET:

103466097(eea1)

PFOR:

103133682(eea1)

PLAI:

106950917(eea1)

PMEI:

106916048(eea1)

GAF:	122835540(eea1)

CVG:	107104245(eea1)

CTUL:

119792993(eea1)

GMU:	124857170(eea1)

NFU:	107388955(eea1)

KMR:	108239968(eea1)

ALIM:

106515606(eea1)

NWH:	119416250(eea1)

AOCE:

111568346(eea1)

MCEP:

125014425(eea1)

CSEM:

103380151(eea1)

POV:	109624407(eea1)

SSEN:

122775574(eea1)

HHIP:

117763345(eea1)

HSP:	118110110(eea1)

LCF:

108875383

SDU:	111228664(eea1)

SLAL:

111655352(eea1)

XGL:	120792950(eea1)

HCQ:	109530335(eea1)

BPEC:

110165609(eea1)

MALB:

109970769(eea1)

BSPL:

114857940(eea1)

SASA:

106561425 106573307

STRU:

115152171 115197367

OTW:	112218997 112232086(eea1)

OMY:	110497706 110522699(eea1)

OGO:	124002522(eea1) 124035099

ONE:	115109551 115134112

SALP:

111952322 111962490

SNH:	120054059(eea1) 120065920

CCLU:

121532249 121577000

ELS:	105022143(eea1)

SFM:	108933905 114909204(eea1)

PKI:	111842391(eea1)

AANG:

118231886(eea1)

LOC:	102682916(eea1)

PSPA:

121318395 121319703

ARUT:

117415488 117419784

PSEX:

120534182(eea1)

LCM:	102357014(EEA1)

CMK:	103188866(eea1)

RTP:	109913816(eea1)

BFO:

118407271

BBEL:

109469988

CIN:	751565(zf(fyve/c2h2)-2)

SPU:

APLC:

SKO:

CSEC:

FCD:

DMK:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

RSAN:

DFR:

CSCU:

CEL:	CELE_T10G3.5(eea-1)

CBR:	CBG_06689(Cbr-eea-1)

LOA:	LOAG_01311

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:	106179935 106181428 106181440

SMM:	Smp_171970

NVE:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

AQU:

SRE:	PTSG_00886 PTSG_03085

» show all

Reference

PMID:20534488

Authors

Mishra A, Eathiraj S, Corvera S, Lambright DG

Title

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).

Journal

Proc Natl Acad Sci U S A 107:10866-71 (2010)
DOI:10.1073/pnas.1000843107

Sequence

[hsa:8411] [mmu:216238]

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