KEGG   ORTHOLOGY: K12490
Entry
K12490                      KO                                     

Name
ARAP3
Definition
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
   04024 cAMP signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Domain-containing proteins not elsewhere classified [BR:ko04990]
 Pleckstrin homology (PH) domain-containing proteins
  Other PH domain-containing proteins
   K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Genes
HSA: 64411(ARAP3)
PTR: 462149(ARAP3)
PPS: 100977768(ARAP3)
GGO: 101137714(ARAP3)
PON: 100437871(ARAP3)
NLE: 100598122(ARAP3)
MCC: 701400(ARAP3)
MCF: 102124624(ARAP3)
CSAB: 103244701(ARAP3)
RRO: 104681826(ARAP3)
RBB: 108530209(ARAP3)
CJC: 100387074(ARAP3)
SBQ: 101037093(ARAP3)
MMU: 106952(Arap3)
MCAL: 110284610(Arap3)
MPAH: 110333208(Arap3)
RNO: 361314(Arap3)
MUN: 110557094(Arap3)
CGE: 100752046(Arap3)
NGI: 103736075(Arap3)
HGL: 101709044(Arap3)
CCAN: 109681337(Arap3)
OCU: 100354264(ARAP3)
TUP: 102470245(ARAP3)
CFA: 487188(ARAP3)
VVP: 112934640(ARAP3)
AML: 100465375(ARAP3)
UMR: 103663721(ARAP3)
UAH: 113255371(ARAP3)
ORO: 101366666(ARAP3)
ELK: 111156922
FCA: 101080259(ARAP3)
PTG: 102962215(ARAP3)
PPAD: 109252207(ARAP3)
AJU: 106968226(ARAP3)
BTA: 112447442(ARAP3)
BOM: 102265022(ARAP3)
BIU: 109561086(ARAP3)
BBUB: 102411515(ARAP3)
CHX: 102184425(ARAP3)
OAS: 101105821(ARAP3)
SSC: 100511744(ARAP3)
CFR: 102511883(ARAP3)
CDK: 105090802(ARAP3)
BACU: 103013330(ARAP3)
LVE: 103082900(ARAP3)
OOR: 101280167(ARAP3)
DLE: 111183025(ARAP3)
PCAD: 102979637(ARAP3)
ECB: 100072169(ARAP3)
EPZ: 103550695(ARAP3)
EAI: 106836965(ARAP3)
MYB: 102253252(ARAP3)
MYD: 102761561(ARAP3)
MNA: 107531508(ARAP3)
HAI: 109393984(ARAP3)
DRO: 112318118(ARAP3)
PALE: 102897313(ARAP3)
RAY: 107499695(ARAP3)
MJV: 108405531(ARAP3)
LAV: 100657212(ARAP3)
TMU: 101357139
MDO: 100027875(ARAP3)
SHR: 100928929(ARAP3)
PCW: 110220838(ARAP3)
OAA: 100076932(ARAP3)
GGA: 416196(ARAP3)
MGP: 100543789(ARAP3)
CJO: 107320281(ARAP3)
NMEL: 110405328(ARAP3)
APLA: 101796955(ARAP3)
ACYG: 106034417(ARAP3)
TGU: 100220646(ARAP3)
LSR: 110480255(ARAP3)
SCAN: 103817415(ARAP3)
GFR: 102032084(ARAP3)
FAB: 101817352(ARAP3)
PHI: 102108475(ARAP3)
PMAJ: 107210565(ARAP3)
CCAE: 111935703(ARAP3)
CCW: 104696073(ARAP3)
ETL: 114066132(ARAP3)
FPG: 101917849(ARAP3)
FCH: 102055065(ARAP3)
CLV: 102092535(ARAP3)
EGZ: 104135761(ARAP3)
NNI: 104016573(ARAP3)
ACUN: 113485333(ARAP3)
PADL: 103921971(ARAP3)
AAM: 106488076(ARAP3)
ASN: 102385140(ARAP3)
AMJ: 102562874(ARAP3)
CMY: 102941861(ARAP3)
CPIC: 101946704(ARAP3)
ACS: 100561635(arap3)
PVT: 110082024(ARAP3)
PBI: 103057750(ARAP3)
PMUR: 107299164(ARAP3)
TSR: 106547848
PMUA: 114601098(ARAP3)
GJA: 107124863
XLA: 108710892 108713296
XTR: 100492779(arap3)
NPR: 108785748(ARAP3)
DRE: 558931(arap3)
SRX: 107717393 107741086
SANH: 107662027 107664716
SGH: 107563596 107598344(arap3)
CCAR: 109069922
IPU: 108269111(arap3)
PHYP: 113528795(arap3)
AMEX: 103033395
EEE: 113573380
TRU: 105418312 115248421
TNG: GSTEN00004670G001
LCO: 104936083(arap3)
MZE: 101467418(arap3)
ONL: 100711520(arap3)
OLA: 101162821(arap3)
XMA: 102237474(arap3)
XCO: 114139599(arap3)
PRET: 103471782(arap3)
CVG: 107082704(arap3)
NFU: 107381061(arap3)
KMR: 108248976(arap3)
ALIM: 106533294
AOCE: 111586047(arap3)
CSEM: 103390798(arap3)
POV: 109643191
LCF: 108891792
SDU: 111233521(arap3)
SLAL: 111665612(arap3)
HCQ: 109508299(arap3)
BPEC: 110168021
MALB: 109956747(arap3)
SASA: 106594768 106604143 106612290
OTW: 112239485
SALP: 111965591 111967067
ELS: 105007474(arap3)
SFM: 108922908(arap3)
PKI: 111836366(arap3)
LCM: 102359686(ARAP3)
CMK: 103184169(arap3)
ISC: IscW_ISCW022193
BMY: Bm1_45680
LOA: LOAG_02146
TAD: TRIADDRAFT_59978
 » show all
Reference
  Authors
Krugmann S, Williams R, Stephens L, Hawkins PT
  Title
ARAP3 is a PI3K- and rap-regulated GAP for RhoA.
  Journal
Curr Biol 14:1380-4 (2004)
DOI:10.1016/j.cub.2004.07.058
Reference
  Authors
Krugmann S, Anderson KE, Ridley SH, Risso N, McGregor A, Coadwell J, Davidson K, Eguinoa A, Ellson CD, Lipp P, Manifava M, Ktistakis N, Painter G, Thuring JW, Cooper MA, Lim ZY, Holmes AB, Dove SK, Michell RH, Grewal A, Nazarian A, Erdjument-Bromage H, Tempst P, Stephens LR, Hawkins PT
  Title
Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.
  Journal
Mol Cell 9:95-108 (2002)
DOI:10.1016/S1097-2765(02)00434-3
  Sequence
[hsa:64411]
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