KEGG ORTHOLOGY: K12641

ORTHOLOGY: K12641

Entry

K12641 KO

Name

LMNA

Definition

lamin A/C

Pathway

ko04210

Apoptosis

ko05410

Hypertrophic cardiomyopathy

ko05412

Arrhythmogenic right ventricular cardiomyopathy

ko05414

Dilated cardiomyopathy

Disease

H00264

Charcot-Marie-Tooth disease

H00294

Dilated cardiomyopathy

H00420

Familial partial lipodystrophy

H00563

Emery-Dreifuss muscular dystrophy

H00590

Congenital muscular dystrophies (CMD/MDC)

H00601

Hutchinson-Gilford progeria syndrome

H00663

Restrictive dermopathy

H00665

Mandibuloacral dysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K12641  LMNA; lamin A/C
09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12641  LMNA; lamin A/C
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K12641  LMNA; lamin A/C
   05414 Dilated cardiomyopathy
    K12641  LMNA; lamin A/C
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12641  LMNA; lamin A/C
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type V: Nuclear lamins
     K12641  LMNA; lamin A/C

Other DBs

GO:

0005638

Genes

HSA:	4000(LMNA)

PTR:	457385(LMNA)

PPS:	100982001(LMNA)

GGO:	101139250(LMNA)

PON:	100432939(LMNA)

NLE:	100603145(LMNA)

MCC:	719414(LMNA)

MCF:	102125659(LMNA)

CSAB:

103223838(LMNA)

RRO:	104664914(LMNA)

RBB:	108515510(LMNA)

CJC:	100401580(LMNA)

SBQ:	101052183(LMNA)

MMU:	16905(Lmna)

MCAL:

110290577(Lmna)

MPAH:

110319753(Lmna)

RNO:	60374(Lmna)

MUN:	110548973(Lmna)

CGE:	100757316(Lmna)

NGI:	103750617(Lmna)

HGL:	101704567(Lmna)

CCAN:

109690469(Lmna)

OCU:	100343574(LMNA)

TUP:	102492596(LMNA)

CFA:	480124(LMNA)

VVP:	112918941(LMNA)

AML:	100469629(LMNA)

UAH:	113245246(LMNA)

ORO:	101383303(LMNA)

ELK:

111138934

FCA:	101086199(LMNA)

PTG:	102967799(LMNA)

PPAD:

109256198(LMNA)

AJU:	106981532(LMNA)

BTA:	404144(LMNA)

BOM:	102280217(LMNA)

BIU:	109553357(LMNA)

BBUB:

102391844(LMNA)

CHX:	102175347(LMNA)

OAS:	101107924(LMNA)

SSC:	100126859(LMNA)

CFR:	102520067(LMNA)

CDK:	105105658(LMNA)

BACU:

103007926(LMNA)

LVE:	103081139(LMNA)

OOR:	101283048(LMNA)

DLE:	111167038(LMNA)

PCAD:

102977546(LMNA)

ECB:	100057663(LMNA)

EPZ:	103548822(LMNA)

EAI:	106828474(LMNA)

MYB:	102262486(LMNA)

MYD:	102769953(LMNA)

MNA:	107543855(LMNA)

HAI:	109393421(LMNA)

DRO:	112317116(LMNA)

PALE:

102884955(LMNA)

RAY:	107521499(LMNA)

MJV:	108405074(LMNA)

LAV:	100662965(LMNA)

TMU:

101345325

MDO:	100017764(LMNA)

SHR:	100923083(LMNA)

PCW:	110211929(LMNA)

OAA:	100083904 100086283(LMNA)

GGA:

396224

CJO:	107324328(LMNA)

APLA:

101797969(LMNA)

ACYG:

106043362 106048973(LMNA)

TGU:	100218522(LMNA)

LSR:	110471509(LMNA)

SCAN:

103823973(LMNA)

GFR:	102031639(LMNA)

FAB:	101813508(LMNA)

PHI:	102101987(LMNA)

PMAJ:

107214592(LMNA)

CCAE:

111934075 111939453(LMNA)

CCW:

104683962

ETL:	114059050 114069941(LMNA)

FPG:	101917244 101917405(LMNA)

FCH:	102046592 102055756(LMNA)

CLV:	102091664 102098438

EGZ:	104124057(LMNA) 104130803

NNI:	104011915(LMNA) 104017250

ACUN:

113490856(LMNA)

PADL:

103913899 103922724

AAM:	106492305(LMNA) 106496418

ASN:	102370910 102375843 102384538

AMJ:	102562008(LMNA) 102562931 102576133 106737550

PSS:	102443460(LMNA) 102448632 102459838

CMY:	102941203 102948145(LMNA)

CPIC:

101932735 101935730 101944059(LMNA) 101949652

ACS:	100553155(lmna)

PVT:	110077295 110091219(LMNA)

PBI:

103057051

PMUR:

107297417(LMNA) 107301596

TSR:

106545779

PMUA:

114584865 114586391(LMNA)

GJA:	107118044(LMNA) 107123876

XLA:	108700440 108700617 373673(lmna.L)

XTR:	733973(lmna)

NPR:	108799663(LMNA)

DRE:	195815(lmna)

SRX:	107723101 107741735

SANH:

107671682 107704890

SGH:	107587813 107598000

CCAR:

109072855 109094578

IPU:	108267994(lmna)

PHYP:

113533930(lmna)

AMEX:

103035739

EEE:

113571231

TRU:	101072260 101077373 115252040

TNG:	GSTEN00003666G001 GSTEN00005141G001 GSTEN00007701G001

LCO:	104928071 104932162(lmna)

NCC:	104941814(lmna) 104964806

MZE:	101466330(lmna) 101476203

ONL:	100696816(lmna) 109200181

OLA:	101160250 101162240(lmna) 101168604

XMA:	102216404 102216697

XCO:	114142322 114155433

PRET:

103473032 103477552(lmna)

CVG:	107090817 107104047(lmna)

NFU:	107379121(lmna) 107394894

KMR:	108248891 108250646

ALIM:

106528028(lmna) 106530099

AOCE:

111569146 111578023(lmna)

CSEM:

103379225 103388831(lmna) 103393959

POV:	109643006(lmna) 109644093

LCF:	108899256 108899430(lmna)

SDU:	111220840 111222569(lmna)

SLAL:

111645579 111655682(lmna)

HCQ:	109513571 109521011(lmna)

BPEC:

110153900 110168861

MALB:

109958689 109974709(lmna)

SASA:

106569771 106580679 106605311

OTW:	112222965 112229479 112230026

SALP:

111954759 111959123 111965113 112079620

ELS:	105007923 105031464(lmna) 114835031

SFM:	108926783(lmna) 108930411

PKI:	111838402(lmna) 111853505

LCM:	102359604(LMNA)

CMK:

RTP:

SPU:

APLC:

SKO:	100378619 102807926

FCD:

CRG:

EGL:

NVE:

ADF:

SPIS:

AQU:	100639783 105313707

SRE:	PTSG_10006

SPAR:

SPRG_14046

» show all

Reference

PMID:20079404

Authors

De Vos WH, Houben F, Hoebe RA, Hennekam R, van Engelen B, Manders EM, Ramaekers FC, Broers JL, Van Oostveldt P

Title

Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.

Journal

Biochim Biophys Acta 1800:448-58 (2010)
DOI:10.1016/j.bbagen.2010.01.002

Sequence

[hsa:4000]

LinkDB

DBGET integrated database retrieval system