KEGG   ORTHOLOGY: K12711
Entry
K12711                      KO                                     

Name
novM, cloM, couM
Definition
L-demethylnoviosyl transferase [EC:2.4.1.302]
Pathway
ko00401  Novobiocin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00401 Novobiocin biosynthesis
    K12711  novM, cloM, couM; L-demethylnoviosyl transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.302  L-demethylnoviosyl transferase
     K12711  novM, cloM, couM; L-demethylnoviosyl transferase
Other DBs
RN: R06767 R06770 R06773
CAZy: GT1
Genes
NGV: CDO52_02205
AG: AAF67506(novM) AAG29785(couM) AAN65229(cloM)
Reference
  Authors
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L
  Title
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
  Journal
Antimicrob Agents Chemother 44:1214-22 (2000)
DOI:10.1128/AAC.44.5.1214-1222.2000
  Sequence
Reference
  Authors
Pojer F, Li SM, Heide L.
  Title
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
  Journal
Microbiology 148:3901-11 (2002)
DOI:10.1099/00221287-148-12-3901
  Sequence
Reference
  Authors
Freel Meyers CL, Oberthur M, Heide L, Kahne D, Walsh CT
  Title
Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN.
  Journal
Biochemistry 43:15022-36 (2004)
DOI:10.1021/bi048457z
LinkDB

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