KEGG   ORTHOLOGY: K12757
Entry
K12757                      KO                                     

Name
MYL12
Definition
myosin regulatory light chain 12
Pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12757  MYL12; myosin regulatory light chain 12
   04530 Tight junction
    K12757  MYL12; myosin regulatory light chain 12
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12757  MYL12; myosin regulatory light chain 12
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K12757  MYL12; myosin regulatory light chain 12
   04670 Leukocyte transendothelial migration
    K12757  MYL12; myosin regulatory light chain 12
  09158 Development and regeneration
   04360 Axon guidance
    K12757  MYL12; myosin regulatory light chain 12
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12757  MYL12; myosin regulatory light chain 12
   05131 Shigellosis
    K12757  MYL12; myosin regulatory light chain 12
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12757  MYL12; myosin regulatory light chain 12
   04147 Exosome
    K12757  MYL12; myosin regulatory light chain 12
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12757  MYL12; myosin regulatory light chain 12
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   K12757  MYL12; myosin regulatory light chain 12
Genes
HSA: 103910(MYL12B) 10627(MYL12A)
PTR: 455313(MYL12B) 455314(MYL12A) 471369
PPS: 100972981 100977910(MYL12B) 100978696(MYL12A)
GGO: 101126168(MYL12B) 101127500 109028042 115934314
PON: 100172271(MYL12A) 100432987 100450310
NLE: 100585479(MYL12B) 100586474(MYL12A)
MCC: 694957(MYL12B) 695077(MYL12A)
MCF: 101926125 102124550(MYL12A)
CSAB: 103222701(MYL12B) 103222703(MYL12A)
RRO: 104654121(MYL12A) 104654122(MYL12B)
RBB: 108533552 108533553(MYL12B)
CJC: 100386818 100409903(MYL12B) 100410505(MYL12B)
MMU: 67268(Myl12a) 67938(Myl12b)
MPAH: 110335458(Myl12b) 110335459
RNO: 501203(Myl12a) 50685(Myl12b)
HGL: 101697884(Myl12b)
CFA: 480193(MYL12B) 607207
UAH: 113253249
PTG: 102971233(MYL12B) 102971525
AJU: 106971575 106971576(MYL12B)
BTA: 531505(MYL12A) 614055(MYL12B)
BOM: 102268971(MYL12B) 102269444
CHX: 102174891 102175348(MYL12B)
OAS: 100270714(MRCL3) 101105123
SSC: 414399(MRLC2) 733637
BACU: 103010250 103010734(MYL12B)
LVE: 103088639 103089268(MYL12B)
DLE: 111162912 111162972(MYL12B)
MYB: 102257812(MYL12B) 102258119
MYD: 102752077(MYL12B) 102752364
TMU: 101349753
MDO: 100012236 100012278(MYL12B)
PCW: 110197071 110197087(MYL12B)
OAA: 100092114
GGA: 396284(MYL12A) 770011(MYL12B)
CJO: 107310048
APLA: 101795371
ACYG: 106034947 106034948(MYL12B)
LSR: 110467854(MYL12B) 110467855
GFR: 102038378(MYL12B)
CCAE: 111923992
CCW: 104687298
ETL: 114058741(MYL12B)
FPG: 101921847(MYL12B) 101922135
CLV: 102098580(MYL12B) 102098877
AMJ: 102560494 102569016(MYL12A)
CMY: 102937279 102938771(MYL12B)
CPIC: 101935947(MYL12B) 101936202
ACS: 100565496
PVT: 110079422
PBI: 103060959
PMUR: 107294002
TSR: 106544631
PMUA: 114600714
GJA: 107118014
XLA: 108695600 380472(myl12b.L)
XTR: 448060(myl12b)
NPR: 108784895
DRE: 326719(myl12.1) 337084(myl12.2)
KMR: 108230493(myl12.1) 108232979(myl12.2)
SASA: 106578694(MLRN) 106590146(MLRN)
LCM: 102346545
CMK: 103183460
RTP: 109927812
DME: Dmel_CG3595(sqh)
DSI: Dsimw501_GD16204(Dsim_sqh)
DYA: Dyak_GE16476(Dyak_sqh) Dyak_GE26184
DVI: 6629928
AALB: 109422051
AME: 550973
BIM: 100745561
BTER: 100644439
CCAL: 108629618
OBB: 114878150
MPHA: 105833233
AEC: 105144770
ACEP: 105621380
PBAR: 105422709
HST: 105186929
DQU: 106749045
CFO: 105255616
LHU: 105672816
PGC: 109853960
OBO: 105274559
NVI: 100115576
CSOL: 105362275
MDL: 103577593
TCA: 658477
DPA: 109542237
ATD: 109604965
NVL: 108561709
PMAC: 106714529
PXY: 105388071
API: 100163913
DNX: 107164171
CLEC: 106664184
ZNE: 110835883
FCD: 110858569
CEL: CELE_C36E6.3(mlc-1) CELE_C36E6.5(mlc-2) CELE_C56G7.1(mlc-4)
CBR: CBG01858(Cbr-mlc-2.2) CBG01859(Cbr-mlc-1) CBG09860(Cbr-mlc-4)
NVE: 5507361
HMG: 100204484
AQU: 100631435
CNE: CNE03510
CNB: CNBE3520
TASA: A1Q1_04366
MRR: Moror_408
ABP: AGABI1DRAFT67432(AGABI1DRAFT_67432)
ABV: AGABI2DRAFT196727(AGABI2DRAFT_196727)
MGL: MGL_3227
MRT: MRET_2467
 » show all
Reference
  Authors
Park I, Han C, Jin S, Lee B, Choi H, Kwon JT, Kim D, Kim J, Lifirsu E, Park WJ, Park ZY, Kim do H, Cho C
  Title
Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.
  Journal
Biochem J 434:171-80 (2011)
DOI:10.1042/BJ20101473
Reference
  Authors
Suizu F, Ueda K, Iwasaki T, Murata-Hori M, Hosoya H
  Title
Activation of actin-activated MgATPase activity of myosin II by phosphorylation with MAPK-activated protein kinase-1b (RSK-2).
  Journal
J Biochem 128:435-40 (2000)
DOI:10.1093/oxfordjournals.jbchem.a022771
Reference
  Authors
Iwasaki T, Murata-Hori M, Ishitobi S, Hosoya H
  Title
Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.
  Journal
Cell Struct Funct 26:677-83 (2001)
DOI:10.1247/csf.26.677
  Sequence
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