KEGG   ORTHOLOGY: K12803
Entry
K12803                      KO                                     

Name
MEFV
Definition
pyrin
Pathway
ko04621  NOD-like receptor signaling pathway
ko05135  Yersinia infection
Disease
H00288  Familial Mediterranean fever
H01516  Adult onset Still disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12803  MEFV; pyrin
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K12803  MEFV; pyrin
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12803  MEFV; pyrin
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    K12803  MEFV; pyrin
Genes
HSA: 4210(MEFV)
PTR: 107968776(MEFV)
PPS: 100975882(MEFV)
GGO: 101135876(MEFV)
PON: 100439051(MEFV)
NLE: 100592337(MEFV)
MCC: 701927(MEFV)
MCF: 102118440(MEFV)
CSAB: 103227338(MEFV)
RRO: 104672305(MEFV)
RBB: 108538309(MEFV)
CJC: 100387055(MEFV)
SBQ: 101045359(MEFV)
MMU: 54483(Mefv)
MCAL: 110311817(Mefv)
MPAH: 110329877(Mefv)
RNO: 58923(Mefv)
MUN: 110545949(Mefv)
CGE: 100771221
NGI: 103744258(Mefv)
HGL: 101701604(Mefv)
CCAN: 109700602(Mefv)
OCU: 100345983(MEFV)
TUP: 102470804(MEFV)
CFA: 490041(MEFV)
VVP: 112909139(MEFV)
AML: 100477997(MEFV)
UMR: 103668524(MEFV)
ORO: 101386793(MEFV)
ELK: 111155992
FCA: 101096694(MEFV)
PTG: 102952100(MEFV)
PPAD: 109278214(MEFV)
AJU: 106978784(MEFV)
BTA: 529195(MEFV)
BOM: 102284489(MEFV)
BIU: 109578320(MEFV)
BBUB: 102398355(MEFV)
CHX: 102186453(MEFV)
OAS: 101121821(MEFV)
SSC: 100517333(MEFV)
CFR: 102523814(MEFV)
CDK: 105099760(MEFV)
BACU: 103000836(MEFV)
LVE: 103075549(MEFV)
OOR: 101286450(MEFV)
DLE: 111185224(MEFV)
PCAD: 102994486(MEFV)
ECB: 100069286(MEFV)
EPZ: 103551604(MEFV)
EAI: 106825976
MYB: 102241361(MEFV)
MYD: 102775012(MEFV)
MNA: 107535793(MEFV)
HAI: 109376759(MEFV)
DRO: 112298335(MEFV)
PALE: 102890576(MEFV)
RAY: 107498781(MEFV)
MJV: 108397047(MEFV)
LAV: 100673509(MEFV)
TMU: 101356110
MDO: 100017024(MEFV)
SHR: 100933206(MEFV)
PCW: 110214642(MEFV)
 » show all
Reference
  Authors
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL
  Title
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis.
  Journal
Mol Cell 11:591-604 (2003)
DOI:10.1016/S1097-2765(03)00056-X
Reference
PMID:9288758
  Title
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium.
  Journal
Cell 90:797-807 (1997)
DOI:10.1016/S0092-8674(00)80539-5
  Sequence
[hsa:4210]
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