KEGG   ORTHOLOGY: K12823Help
Entry
K12823                      KO                                     

Name
DDX5, DBP2
Definition
ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
Pathway
ko03040  Spliceosome
ko05202  Transcriptional misregulation in cancer
ko05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
   05205 Proteoglycans in cancer
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
   03009 Ribosome biogenesis
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.13  RNA helicase
     K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
Spliceosome [BR:ko03041]
 Complex A
  U1 snRNP components
   U1 related factors
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
 Complex B
  U1 snRNP components
   U1 related factors
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
Ribosome biogenesis [BR:ko03009]
 Eukaryotic Type
  Pre-60S particles
   Helicases
    K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2
BRITE hierarchy
Other DBs
COG: COG0513
GO: 0004004
Genes
HSA: 1655(DDX5)
PTR: 455267(DDX5)
PPS: 100978225(DDX5)
GGO: 101134914(DDX5)
PON: 100173977(DDX5)
NLE: 100603290(DDX5)
MCC: 677694(DDX5)
MCF: 101926602(DDX5)
CSAB: 103243195(DDX5)
RRO: 104675440(DDX5)
RBB: 108536250(DDX5)
CJC: 100396762(DDX5)
SBQ: 101044489(DDX5)
MMU: 13207(Ddx5)
MCAL: 110304573(Ddx5) 110304788
MPAH: 110332239(Ddx5)
RNO: 287765(Ddx5)
MUN: 110547035(Ddx5)
CGE: 100768812(Ddx5)
NGI: 103737020 103740926(Ddx5)
HGL: 101707835(Ddx5)
CCAN: 109695678(Ddx5)
OCU: 100351285(DDX5)
TUP: 102503342(DDX5)
CFA: 480472(DDX5)
VVP: 112920717(DDX5)
AML: 100470124(DDX5)
UMR: 103665648(DDX5)
UAH: 113265269(DDX5)
ORO: 101369034(DDX5)
FCA: 101099414(DDX5)
PTG: 102958949(DDX5)
AJU: 106975324(DDX5)
BTA: 533700(DDX5)
BOM: 102276598(DDX5)
BIU: 109573510(DDX5)
BBUB: 102388941(DDX5)
PHD: 102318131(DDX5)
CHX: 102181158(DDX5)
OAS: 101106186(DDX5)
SSC: 102158045(DDX5)
CFR: 102520084(DDX5)
CDK: 105092310(DDX5)
BACU: 103013532(DDX5)
LVE: 103080033(DDX5)
OOR: 101286900(DDX5)
DLE: 111182637(DDX5)
ECB: 100064168(DDX5)
EPZ: 103549743(DDX5)
EAI: 106835550(DDX5)
MYB: 102246453 102256138(DDX5)
MYD: 102770447(DDX5)
MNA: 107530740(DDX5)
HAI: 109380301(DDX5)
RSS: 109441688 109448030(DDX5)
DRO: 112316464(DDX5)
PALE: 102895749(DDX5)
LAV: 100668198(DDX5)
TMU: 101351668
MDO: 100029630(DDX5)
SHR: 100916651(DDX5)
PCW: 110218199(DDX5)
OAA: 100079853(DDX5)
GGA: 395629(DDX5)
MGP: 100542962(DDX5)
CJO: 107322006(DDX5)
APLA: 101804362(DDX5)
ACYG: 106034801(DDX5)
TGU: 100223125(DDX5)
LSR: 110474209(DDX5)
SCAN: 103819779(DDX5)
GFR: 102042647(DDX5)
FAB: 101806908(DDX5)
PHI: 102102952(DDX5)
PMAJ: 107212364(DDX5)
CCAE: 111937419(DDX5)
ETL: 114065997(DDX5)
FPG: 101924399(DDX5)
FCH: 102054453(DDX5)
CLV: 102084479(DDX5)
EGZ: 104123765(DDX5)
NNI: 104014368(DDX5)
ACUN: 113486716(DDX5)
AAM: 106493123(DDX5)
ASN: 102387659(DDX5)
AMJ: 102567395(DDX5)
PSS: 102457904(DDX5)
CMY: 102943978(DDX5)
CPIC: 101944072(DDX5)
ACS: 100567536(ddx5)
PVT: 110073352(DDX5)
PBI: 103052053(DDX5)
PMUR: 107284850(DDX5)
GJA: 107120926(DDX5)
XLA: 379390(ddx5.S) 399382(ddx5.L)
XTR: 394837(ddx5)
NPR: 108797646(DDX5)
DRE: 322206(ddx5)
IPU: 108257112 108273114(ddx5)
NCC: 104944580(ddx5) 104957960
NFU: 107376252 107382295(ddx5)
BPEC: 110166139(ddx5) 110172211
ELS: 105013158 105021634(ddx5)
PKI: 111843288 111848129(ddx5)
LCM: 102362755(DDX5)
CMK: 103175604(ddx5)
SPU: 578813
DME: Dmel_CG10077(CG10077) Dmel_CG10279(Rm62) Dmel_CG10777(mahe) Dmel_CG14443(CG14443)
DSI: Dsimw501_GD13105(Dsim_GD13105) Dsimw501_GD16140(Dsim_GD16140) Dsimw501_GD29077(Dsim_GD29077)
TCA: 100141769(Rm62) 103312134
CEL: CELE_F58E10.3(ddx-17)
CBR: CBG11408
CRG: 105340428
MYI: 110453909
OBI: 106880622
SHX: MS3_05366
EGL: EGR_00515
SPIS: 111324739
LJA: Lj0g3v0060759.1(Lj0g3v0060759.1) Lj2g3v1451720.1(Lj2g3v1451720.1) Lj3g3v0306870.1(Lj3g3v0306870.1) Lj4g3v1440690.1(Lj4g3v1440690.1) Lj6g3v1586670.1(Lj6g3v1586670.1) Lj6g3v1586670.2(Lj6g3v1586670.2)
DOSA: Os01t0172200-01(Os01g0172200) Os01t0197200-01(Os01g0197200) Os01t0549400-01(Os01g0549400) Os01t0911100-01(Os01g0911100) Os11t0689400-00(Os11g0689400)
ATS: 109738726(LOC109738726) 109740785(LOC109740785) 109756743(LOC109756743) 109756807(LOC109756807) 109776680(LOC109776680)
APRO: F751_6986
SCE: YNL112W(DBP2)
ERC: Ecym_5422
KMX: KLMA_60235(DBP2)
NCS: NCAS_0G02560(NCAS0G02560)
NDI: NDAI_0F02740(NDAI0F02740)
TPF: TPHA_0B02930(TPHA0B02930)
TBL: TBLA_0C05580(TBLA0C05580)
TDL: TDEL_0F01190(TDEL0F01190)
KAF: KAFR_0B04560(KAFR0B04560)
PIC: PICST_82821(DBP2)
CAL: CAALFM_CR02530WA(DBP2)
SLB: AWJ20_3134(DBP2)
NCR: NCU07839
NTE: NEUTE1DRAFT62235(NEUTE1DRAFT_62235)
MGR: MGG_16901
MAW: MAC_01654
MAJ: MAA_02487
CMT: CCM_09438
MBE: MBM_07085
ANI: AN5931.2
ANG: ANI_1_342024(An02g02530)
PBN: PADG_11254(PADG_01384)
ABE: ARB_05225
TVE: TRV_02264
PNO: SNOG_08367(SNOG_08365 SNOG_08366)
PTE: PTT_11286
SPO: SPBP8B7.16c(dbp2)
CNE: CNF01240
CNB: CNBF3470
ABP: AGABI1DRAFT100622(AGABI1DRAFT_100622)
ABV: AGABI2DRAFT65810(AGABI2DRAFT_65810)
MGL: MGL_3203
MBR: MONBRDRAFT_21564(p68DDX5)
EHI: EHI_096390(6.t00035)
PYO: PY17X_1313500(PY01901) PY17X_1444400(PY04046)
PCB: PCHAS_131290(PC000114.00.0) PCHAS_144390(PC000235.05.0)
TPV: TP04_0562
BBO: BBOV_II004470(18.m06373)
CPV: cgd2_1010
TGO: TGME49_236650(DDX17)
SMIN: v1.2.002851.t1(symbB.v1.2.002851.t1) v1.2.003131.t1(symbB.v1.2.003131.t1) v1.2.003132.t1(symbB.v1.2.003132.t1) v1.2.005147.t1(symbB.v1.2.005147.t1) v1.2.005543.t1(symbB.v1.2.005543.t1) v1.2.007755.t1(symbB.v1.2.007755.t1) v1.2.010179.t1(symbB.v1.2.010179.t1) v1.2.010925.t1(symbB.v1.2.010925.t1) v1.2.011316.t1(symbB.v1.2.011316.t1) v1.2.012888.t1(symbB.v1.2.012888.t1) v1.2.015375.t1(symbB.v1.2.015375.t1) v1.2.017056.t1(symbB.v1.2.017056.t1) v1.2.017282.t1(symbB.v1.2.017282.t1) v1.2.019349.t1(symbB.v1.2.019349.t1) v1.2.022519.t1(symbB.v1.2.022519.t1) v1.2.023878.t1(symbB.v1.2.023878.t1) v1.2.025384.t1(symbB.v1.2.025384.t1) v1.2.025946.t1(symbB.v1.2.025946.t1) v1.2.027049.t1(symbB.v1.2.027049.t1) v1.2.027049.t2(symbB.v1.2.027049.t2) v1.2.029971.t1(symbB.v1.2.029971.t1) v1.2.030998.t1(symbB.v1.2.030998.t1) v1.2.034428.t1(symbB.v1.2.034428.t1) v1.2.037562.t1(symbB.v1.2.037562.t1) v1.2.040112.t1(symbB.v1.2.040112.t1) v1.2.040112.t2(symbB.v1.2.040112.t2) v1.2.040626.t1(symbB.v1.2.040626.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Endoh H, Maruyama K, Masuhiro Y, Kobayashi Y, Goto M, Tai H, Yanagisawa J, Metzger D, Hashimoto S, Kato S
  Title
Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha.
  Journal
Mol Cell Biol 19:5363-72 (1999)
DOI:10.1128/MCB.19.8.5363
  Sequence
[hsa:1655]
Reference
  Authors
Kar A, Fushimi K, Zhou X, Ray P, Shi C, Chen X, Liu Z, Chen S, Wu JY
  Title
RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site.
  Journal
Mol Cell Biol 31:1812-21 (2011)
DOI:10.1128/MCB.01149-10
  Sequence
[hsa:1655]
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