KEGG   ORTHOLOGY: K14367
Entry
K14367                      KO                                     
Symbol
eryBV
Name
erythronolide mycarosyltransferase [EC:2.4.1.328]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00774  Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
Reaction
R05530  dTDP-L-mycarose:erythronolide-B 3-O-alpha-mycarosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K14367  eryBV; erythronolide mycarosyltransferase
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K14367  eryBV; erythronolide mycarosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14367  eryBV; erythronolide mycarosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.328  erythronolide mycarosyltransferase
     K14367  eryBV; erythronolide mycarosyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K14367  eryBV; erythronolide mycarosyltransferase
Other DBs
CAZy: GT1
Genes
SNR: SNOUR_10200
SGF: HEP81_07917
AER: AERYTH_15935
SEN: SACE_0719(eryBV)
AEY: CDG81_13195
AG: AAG13915(megBV)
Reference
PMID:9353926
  Authors
Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L.
  Title
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.
  Journal
Microbiology 143:3251-62 (1997)
DOI:10.1099/00221287-143-10-3251
  Sequence
[sen:SACE_0719]
Reference
PMID:9393448
  Authors
Gaisser S, Bohm GA, Cortes J, Leadlay PF
  Title
Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.
  Journal
Mol Gen Genet 256:239-51 (1997)
DOI:10.1007/s004380050566
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