KEGG   ORTHOLOGY: K15498Help
Entry
K15498                      KO                                     

Name
PPP6C
Definition
serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-6
    Catalytic subunits
     K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   Other DSBR factors
    Protein phosphatase 6
     K15498  PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
BRITE hierarchy
Other DBs
GO: 0004722
Genes
HSA: 5537(PPP6C)
PTR: 738446(PPP6C)
PPS: 100990089(PPP6C)
GGO: 101148097(PPP6C)
PON: 100454711(PPP6C)
NLE: 100599813(PPP6C)
MCC: 703658(PPP6C)
MCF: 101926754(PPP6C)
CSAB: 103239872(PPP6C)
RRO: 104664382(PPP6C)
RBB: 108531355(PPP6C)
CJC: 100388758(PPP6C)
SBQ: 101039985(PPP6C)
MMU: 67857(Ppp6c)
MCAL: 110289422(Ppp6c)
MPAH: 110317576(Ppp6c)
RNO: 171121(Ppp6c)
MUN: 110546503(Ppp6c)
CGE: 100752643(Ppp6c)
NGI: 103727013(Ppp6c) 103746870
HGL: 101714279(Ppp6c)
CCAN: 109683430(Ppp6c)
OCU: 100341981(PPP6C)
TUP: 102474158(PPP6C)
CFA: 608922(PPP6C)
VVP: 112927877(PPP6C)
AML: 100479321(PPP6C)
UMR: 103670456(PPP6C)
UAH: 113266407(PPP6C)
ORO: 101369718 101381503(PPP6C)
FCA: 101082527(PPP6C)
PTG: 102950841(PPP6C)
PPAD: 109250168(PPP6C)
AJU: 106965854(PPP6C)
BTA: 511058(PPP6C)
BOM: 102284131(PPP6C)
BIU: 109566465(PPP6C)
BBUB: 102413325(PPP6C)
CHX: 102184162(PPP6C)
OAS: 101106922(PPP6C)
SSC: 100153256(PPP6C)
CFR: 102524360(PPP6C)
CDK: 105092627(PPP6C)
BACU: 103020204(PPP6C)
LVE: 103073655(PPP6C)
OOR: 101289799(PPP6C)
DLE: 111177219(PPP6C)
PCAD: 102984506(PPP6C)
ECB: 100070914(PPP6C)
EPZ: 103552117(PPP6C)
EAI: 106830824(PPP6C)
MYB: 102251772(PPP6C)
MYD: 102765139(PPP6C)
MNA: 107535484(PPP6C)
HAI: 109379547(PPP6C)
DRO: 112306262(PPP6C)
PALE: 102894507(PPP6C)
RAY: 107506637(PPP6C)
MJV: 108405649(PPP6C)
LAV: 100665869(PPP6C)
TMU: 101361685
MDO: 100015864(PPP6C)
SHR: 100923302(PPP6C)
PCW: 110194943(PPP6C)
OAA: 100074888(PPP6C)
GGA: 772354(PPP6C)
MGP: 100549079(PPP6C)
CJO: 107321944(PPP6C)
NMEL: 110406906(PPP6C)
APLA: 101789972(PPP6C)
ACYG: 106040669(PPP6C)
TGU: 100227861(PPP6C)
LSR: 110477680(PPP6C)
SCAN: 103819099(PPP6C)
GFR: 102036026(PPP6C)
FAB: 101811732(PPP6C)
PHI: 102106640(PPP6C)
PMAJ: 107211900(PPP6C)
CCAE: 111922177(PPP6C)
CCW: 104688393(PPP6C)
ETL: 114061989(PPP6C)
FPG: 101913705(PPP6C)
FCH: 102047681(PPP6C)
CLV: 102090247(PPP6C)
EGZ: 104134042(PPP6C)
NNI: 104023328(PPP6C)
ACUN: 113486570(PPP6C)
PADL: 103925637(PPP6C)
AAM: 106495038(PPP6C)
ASN: 102381608(PPP6C)
AMJ: 102572804(PPP6C)
PSS: 102460156(PPP6C)
CMY: 102941330(PPP6C)
CPIC: 101941592(PPP6C)
ACS: 100560299(ppp6c)
PVT: 110082968(PPP6C)
PBI: 103067969(PPP6C)
PMUR: 107296772(PPP6C)
TSR: 106540103(PPP6C)
PMUA: 114589527(PPP6C)
GJA: 107119959(PPP6C)
XLA: 108700017 734439(ppp6c.L)
XTR: 549864(ppp6c)
DRE: 393980(ppp6c)
IPU: 108280420(ppp6c)
PHYP: 113531305(ppp6c)
AMEX: 103047394(ppp6c)
EEE: 113583625(ppp6c)
TRU: 101071879(ppp6c)
LCO: 104928043 104937056(ppp6c)
NCC: 104942171 104953936(ppp6c)
ONL: 100701794 100710879(ppp6c)
XMA: 102227303 102232066(ppp6c)
XCO: 114150147 114155078(ppp6c)
CVG: 107088006(ppp6c) 107093923
NFU: 107375007 107393462(ppp6c)
POV: 109639099(ppp6c)
SDU: 111221153 111222779(ppp6c)
HCQ: 109510550(ppp6c)
BPEC: 110161396(ppp6c) 110163331
MALB: 109959752(ppp6c) 109970929
ELS: 105006805(ppp6c) 105014157
PKI: 111858773(ppp6c) 111859009
LCM: 102361843(PPP6C)
CMK: 103189197(ppp6c)
RTP: 109913842(ppp6c)
CIN: 100177460
SKO: 102801803
DME: Dmel_CG12217(PpV)
DER: 6551380
DSI: Dsimw501_GD26791(Dsim_GD26791)
DPE: 6600035
DWI: 6644539
MDE: 101900920
LCQ: 111681255
AAG: 5564487
AALB: 109425135
AME: 410924
BIM: 100741164
BTER: 100643958
OBB: 114871743
SOC: 105194372
MPHA: 105837760
AEC: 105147459
ACEP: 105624572
PBAR: 105426991
VEM: 105564703
HST: 105190007
DQU: 106748533
CFO: 105250092
LHU: 105668147
PGC: 109854457
OBO: 105275047
PCF: 106793806
NVI: 100120045
CSOL: 105364179
MDL: 103571371
TCA: 655658
ATD: 109596490
NVL: 108569842
BMOR: 732977
PMAC: 106719559
PRAP: 111004266
HAW: 110374431
TNL: 113494478
PXY: 105398558
API: 100169448(Ppp6c)
AGS: 114128831
RMD: 113552023
BTAB: 109036104
CLEC: 106667813
ZNE: 110831236
FCD: 110847788
PVM: 113803807
TUT: 107362714
DPTE: 113797450
CSCU: 111622968
PTEP: 107449256
CEL: CELE_C34C12.3(pph-6)
CBR: CBG09794(Cbr-pph-6)
BMY: Bm1_03950
PCAN: 112571040
CRG: 105332168
MYI: 110459360
OBI: 106880958
EGL: EGR_05527
EPA: 110232970
ADF: 107358722
AMIL: 114957407
PDAM: 113681460
SPIS: 111322020
ATH: AT1G50370(FYPP1) AT3G19980(FYPP3)
CPAP: 110806404
CIT: 102615860
TCC: 18608428
EGR: 104421192
CAM: 101515338
LJA: Lj5g3v2263930.1(Lj5g3v2263930.1)
ADU: 107471896
AIP: 107622788
FVE: 101305656
RCN: 112197313
PPER: 18791596
PMUM: 103321116
PAVI: 110763902
PXB: 103943242
ZJU: 107421889
CSV: 101213373
CMO: 103488787
MCHA: 111010088
RCU: 8260739
JCU: 105631157
QSU: 112040853
VVI: 100852922
LSV: 111903028
CCAV: 112509700
BVG: 104902517
SOE: 110782132
OSA: 4325641
DOSA: Os01t0691700-01(Os01g0691700)
OBR: 102716263
ATS: 109764915(LOC109764915) 109771437(LOC109771437)
SBI: 8063094
ZMA: 100274310(cl12356_1) 100382798
DCT: 110113909
PEQ: 110029094
ATR: 18438403
SMO: SELMODRAFT_232099(FYPP3-1) SELMODRAFT_270060(FYPP-2)
CRE: CHLREDRAFT_144867(PPA1)
MNG: MNEG_7676
CNE: CND05500
CNB: CNBD0860
ABP: AGABI1DRAFT122533(AGABI1DRAFT_122533)
ABV: AGABI2DRAFT187853(AGABI2DRAFT_187853)
MGL: MGL_0981
MRT: MRET_3171
DDI: DDB_G0272118(ppp6C)
DFA: DFA_04730(ppp6C)
EHI: EHI_006050(83.t00018) EHI_147500(51.t00010)
PYO: PY17X_0415000(PY02284)
PCB: PCHAS_041300(PC301193.00.0)
SMIN: v1.2.026143.t1(symbB.v1.2.026143.t1)
SPAR: SPRG_01488
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Zhong J, Liao J, Liu X, Wang P, Liu J, Hou W, Zhu B, Yao L, Wang J, Li J, Stark JM, Xie Y, Xu X
  Title
Protein phosphatase PP6 is required for homology-directed repair of DNA double-strand breaks.
  Journal
Cell Cycle 10:1411-9 (2011)
DOI:10.4161/cc.10.9.15479
  Sequence
[hsa:5537]
Reference
  Authors
Douglas P, Zhong J, Ye R, Moorhead GB, Xu X, Lees-Miller SP
  Title
Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.
  Journal
Mol Cell Biol 30:1368-81 (2010)
DOI:10.1128/MCB.00741-09
  Sequence
[hsa:5537]
Reference
  Authors
Zeng K, Bastos RN, Barr FA, Gruneberg U
  Title
Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2.
  Journal
J Cell Biol 191:1315-32 (2010)
DOI:10.1083/jcb.201008106
  Sequence
[hsa:5537]
Reference
  Authors
Filali M, Li S, Kim HW, Wadzinski B, Kamoun M
  Title
Identification of a type 6 protein ser/thr phosphatase regulated by interleukin-2 stimulation.
  Journal
  Sequence
[hsa:5537]
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