KEGG   ORTHOLOGY: K15907
Entry
K15907                      KO                                     
Symbol
ptlI, CYP183A
Name
pentalenene oxygenase [EC:1.14.15.32]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Reaction
R09814  pentalenene,reduced ferredoxin:oxygen 13-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K15907  ptlI, CYP183A; pentalenene oxygenase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K15907  ptlI, CYP183A; pentalenene oxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K15907  ptlI, CYP183A; pentalenene oxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.32  pentalenene oxygenase
     K15907  ptlI, CYP183A; pentalenene oxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP183 family
   K15907  ptlI, CYP183A; pentalenene oxygenase
Other DBs
COG: COG2124
Genes
SMA: SAVERM_2999(ptlI)
SBH: SBI_09680(cyp48)
SDV: BN159_1442(ptlI)
SCI: B446_29700
SCW: TU94_27410
SLE: sle_13150(sle_13150)
SCLF: BB341_00225
SSIA: A7J05_09235
SALF: SMD44_00690(ptlI)
SALJ: SMD11_0076(ptlI) SMD11_6153(ptlI)
SFEU: IM697_14465
SGJ: IAG43_27160
SHK: J2N69_35800
SFP: QUY26_08865 QUY26_37035
SCT: SCAT_p0090(ptlI)
SCY: SCATT_p16540
KSK: KSE_03600
 » show all
Reference
PMID:17017767 (CYP183A1)
  Authors
Quaderer R, Omura S, Ikeda H, Cane DE
  Title
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis.
  Journal
J Am Chem Soc 128:13036-7 (2006)
DOI:10.1021/ja0639214
  Sequence
[sma:SAVERM_2999]
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