KEGG   ORTHOLOGY: K17454Help
Entry
K17454                      KO                                     

Name
E2F1
Definition
transcription factor E2F1
Pathway
ko01522  Endocrine resistance
ko04110  Cell cycle
ko04137  Mitophagy - animal
ko04218  Cellular senescence
ko04934  Cushing syndrome
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05163  Human cytomegalovirus infection
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05206  MicroRNAs in cancer
ko05212  Pancreatic cancer
ko05214  Glioma
ko05215  Prostate cancer
ko05218  Melanoma
ko05219  Bladder cancer
ko05220  Chronic myeloid leukemia
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K17454  E2F1; transcription factor E2F1
  09143 Cell growth and death
   04110 Cell cycle
    K17454  E2F1; transcription factor E2F1
   04218 Cellular senescence
    K17454  E2F1; transcription factor E2F1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K17454  E2F1; transcription factor E2F1
   05206 MicroRNAs in cancer
    K17454  E2F1; transcription factor E2F1
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K17454  E2F1; transcription factor E2F1
   05225 Hepatocellular carcinoma
    K17454  E2F1; transcription factor E2F1
   05226 Gastric cancer
    K17454  E2F1; transcription factor E2F1
   05214 Glioma
    K17454  E2F1; transcription factor E2F1
   05220 Chronic myeloid leukemia
    K17454  E2F1; transcription factor E2F1
   05218 Melanoma
    K17454  E2F1; transcription factor E2F1
   05219 Bladder cancer
    K17454  E2F1; transcription factor E2F1
   05215 Prostate cancer
    K17454  E2F1; transcription factor E2F1
   05224 Breast cancer
    K17454  E2F1; transcription factor E2F1
   05222 Small cell lung cancer
    K17454  E2F1; transcription factor E2F1
   05223 Non-small cell lung cancer
    K17454  E2F1; transcription factor E2F1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K17454  E2F1; transcription factor E2F1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K17454  E2F1; transcription factor E2F1
   05161 Hepatitis B
    K17454  E2F1; transcription factor E2F1
   05160 Hepatitis C
    K17454  E2F1; transcription factor E2F1
   05163 Human cytomegalovirus infection
    K17454  E2F1; transcription factor E2F1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K17454  E2F1; transcription factor E2F1
   05169 Epstein-Barr virus infection
    K17454  E2F1; transcription factor E2F1
   05165 Human papillomavirus infection
    K17454  E2F1; transcription factor E2F1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K17454  E2F1; transcription factor E2F1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K17454  E2F1; transcription factor E2F1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix cell cycle-controlling factors, E2F
    K17454  E2F1; transcription factor E2F1
BRITE hierarchy
Genes
HSA: 1869(E2F1)
PTR: 107969994(E2F1)
PPS: 100983073(E2F1)
GGO: 101137595(E2F1)
PON: 100435851(E2F1)
NLE: 100601097(E2F1)
MCC: 714126(E2F1)
MCF: 102146018(E2F1)
CSAB: 103248605(E2F1)
RRO: 104660298(E2F1)
RBB: 108533038(E2F1)
CJC: 100414261(E2F1)
SBQ: 101029045(E2F1)
MMU: 13555(E2f1)
MCAL: 110289983(E2f1)
MPAH: 110318578(E2f1)
RNO: 399489(E2f1)
MUN: 110554547(E2f1)
CGE: 100758556(E2f1)
NGI: 103751571(E2f1)
HGL: 101717980(E2f1)
CCAN: 109690765(E2f1)
OCU: 100356957(E2F1)
TUP: 102484832(E2F1)
CFA: 485839(E2F1)
VVP: 112928157(E2F1)
UMR: 103674455(E2F1)
UAH: 113258272(E2F1)
ORO: 101366721(E2F1)
FCA: 101098454(E2F1)
PTG: 102963506(E2F1)
PPAD: 109272548(E2F1)
AJU: 106974609(E2F1)
BTA: 535369(E2F1)
BOM: 102274863(E2F1)
BIU: 109567683(E2F1)
BBUB: 102390395(E2F1)
CHX: 102173018(E2F1)
OAS: 101117526(E2F1)
SSC: 100153846(E2F1)
CFR: 102511223 102517851(E2F1)
CDK: 105092697(E2F1)
BACU: 103015828(E2F1)
LVE: 103070408(E2F1)
OOR: 101275686(E2F1)
DLE: 111184273(E2F1)
PCAD: 102993481(E2F1)
ECB: 100069192(E2F1)
EPZ: 103541516(E2F1)
EAI: 106823225(E2F1)
MYB: 102242618(E2F1)
MYD: 102759026(E2F1)
MNA: 107527747(E2F1)
HAI: 109377242(E2F1)
DRO: 112303722(E2F1)
PALE: 102895276(E2F1)
RAY: 107519491(E2F1)
MJV: 108401113(E2F1)
LAV: 100664468(E2F1)
TMU: 101357348
MDO: 100032280(E2F1)
PCW: 110216806(E2F1)
OAA: 100087014(E2F1)
GGA: 396142(E2F1)
MGP: 100544202(E2F1)
CJO: 107322866(E2F1)
NMEL: 110408351(E2F1)
APLA: 101801576(E2F1)
ACYG: 106047751(E2F1)
TGU: 115497941(E2F1)
LSR: 110475930(E2F1)
SCAN: 103818778(E2F1)
GFR: 102032688(E2F1)
FAB: 101808436(E2F1)
PHI: 102114020(E2F1)
CCAE: 111943945(E2F1)
CCW: 104687904(E2F1)
ETL: 114057267(E2F1)
FPG: 101912302(E2F1)
FCH: 102052559(E2F1)
CLV: 102096538(E2F1)
EGZ: 104124989(E2F1)
NNI: 104019977(E2F1)
PADL: 103912425(E2F1)
AAM: 106496602(E2F1)
ASN: 102379028(E2F1)
AMJ: 102576551(E2F1)
PSS: 102448890(E2F1)
CMY: 102941250(E2F1)
CPIC: 101946215(E2F1)
ACS: 100562223(e2f1)
PVT: 110090563(E2F1)
PBI: 103052541(E2F1)
PMUR: 107294015(E2F1)
TSR: 106550369(E2F1)
PMUA: 114599500(E2F1)
GJA: 107122240(E2F1)
XLA: 100036852(e2f1.L) 108702783(e2f1.S)
XTR: 100493924(e2f1)
NPR: 108786119(E2F1)
DRE: 101885420(e2f1)
CCAR: 109098512(e2f1) 109106942
IPU: 108275488(e2f1)
PHYP: 113530396(e2f1)
AMEX: 103022816(e2f1)
EEE: 113582354(e2f1)
TRU: 101061025(e2f1)
LCO: 104929162(e2f1)
NCC: 104951480(e2f1)
MZE: 101472732(e2f1)
ONL: 100697698(e2f1)
OLA: 101159192(e2f1)
XMA: 102233776(e2f1)
XCO: 114145865(e2f1)
PRET: 103466857(e2f1)
CVG: 107098766(e2f1)
NFU: 107391318(e2f1)
KMR: 108233019(e2f1)
ALIM: 106522384(e2f1)
AOCE: 111571778(e2f1)
CSEM: 103384742(e2f1)
POV: 109630589
LCF: 108882652(e2f1)
SDU: 111230697(e2f1)
SLAL: 111655259(e2f1)
HCQ: 109511673(e2f1)
BPEC: 110158087
MALB: 109967120(e2f1)
ELS: 105022766(e2f1)
SFM: 108939107(e2f1)
PKI: 111842303(e2f1)
LCM: 102358341(E2F1)
CMK: 103188611(e2f1)
RTP: 109915257(e2f1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1638634
  Authors
Helin K, Lees JA, Vidal M, Dyson N, Harlow E, Fattaey A
  Title
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F.
  Journal
Cell 70:337-50 (1992)
DOI:10.1016/0092-8674(92)90107-N
  Sequence
[hsa:1869]
Reference
  Authors
Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P
  Title
An E2F/miR-20a autoregulatory feedback loop.
  Journal
J Biol Chem 282:2135-43 (2007)
DOI:10.1074/jbc.M608939200
  Sequence
[hsa:1869]
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