KEGG   ORTHOLOGY: K17943
Entry
K17943                      KO                                     
Symbol
PUM
Name
pumilio RNA-binding family
Pathway
map05017  Spinocerebellar ataxia
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K17943  PUM; pumilio RNA-binding family
Other DBs
COG: COG5099
GO: 0003730
Genes
HSA: 23369(PUM2) 9698(PUM1)
PTR: 459053(PUM2) 469256(PUM1)
PPS: 100985961(PUM2) 100996178(PUM1)
GGO: 101127804(PUM2) 101138133(PUM1)
PON: 100174674(PUM1) 100444313(PUM2)
NLE: 100581990(PUM1) 100605272(PUM2)
MCC: 701782(PUM2) 704848(PUM1)
MCF: 101925885(PUM1) 102125634(PUM2)
CSAB: 103220720(PUM2) 103225232(PUM1)
CATY: 105578573(PUM2) 105594850(PUM1)
PANU: 101020962(PUM1) 101026134(PUM2)
TGE: 112604552(PUM2) 112608941(PUM1)
RRO: 104654311(PUM2) 104654406(PUM1)
RBB: 108518574(PUM1) 108543045(PUM2)
TFN: 117062676(PUM2) 117092981(PUM1)
PTEH: 111547585(PUM1) 111554493(PUM2)
CJC: 100390681(PUM2) 100415491(PUM1)
SBQ: 101030979(PUM2) 101053153(PUM1)
CSYR: 103262508(PUM2) 103268679(PUM1)
MMUR: 105867354(PUM1) 105884036(PUM2) 105884446
OGA: 100950672(PUM1) 100951133(PUM2)
MMU: 80912(Pum1) 80913(Pum2)
MCAL: 110293213(Pum1) 110306728(Pum2)
MPAH: 110323936(Pum1) 110324324(Pum2)
RNO: 298874(Pum2) 362609(Pum1)
MCOC: 116080597(Pum2) 116096733(Pum1)
MUN: 110548266(Pum1) 110558070(Pum2)
CGE: 100765502(Pum1) 100775042(Pum2)
PLEU: 114691991(Pum2) 114705656(Pum1)
NGI: 103726593(Pum2) 103732564(Pum1)
HGL: 101698365(Pum1) 101724249(Pum2)
CPOC: 100717479(Pum2) 100735839(Pum1)
CCAN: 109681744(Pum1) 109681750(Pum2)
DORD: 105983602(Pum2) 105999361(Pum1)
DSP: 122108821(Pum2) 122121474(Pum1)
OCU: 100348757(PUM1) 100358505(PUM2)
OPI: 101524939(PUM2) 101528168(PUM1)
TUP: 102478492(PUM1) 102495453(PUM2)
CFA: 478158(PUM1) 607618(PUM2)
VVP: 112931814(PUM1) 112932143(PUM2)
VLG: 121490492(PUM2) 121496502(PUM1)
AML: 100469309(PUM2) 100482613(PUM1)
UMR: 103666466(PUM1) 103671700(PUM2)
UAH: 113268391(PUM1) 113270269(PUM2)
UAR: 123782326(PUM1) 123802623(PUM2)
MPUF: 101681394(PUM2) 101691815(PUM1)
ORO: 101374611(PUM1) 101375290(PUM2)
EJU: 114206001(PUM2) 114217196(PUM1)
ZCA: 113935738(PUM1) 113938307(PUM2)
MLX: 118007627(PUM2) 118019777(PUM1)
FCA: 101093375(PUM1) 101099630(PUM2)
PYU: 121024940(PUM1) 121044167(PUM2)
PBG: 122480204(PUM1) 122497419(PUM2)
PTG: 102959243(PUM1) 102961488(PUM2)
PPAD: 109255258(PUM1) 109267980(PUM2)
AJU: 106976433(PUM2) 106981663(PUM1)
HHV: 120222388(PUM2) 120230640(PUM1)
BTA: 535450(PUM1) 540170(PUM2)
BOM: 102275981(PUM2) 102278749(PUM1)
BIU: 109566352(PUM2) 109572615(PUM1)
BBUB: 102400312(PUM1) 102401038(PUM2)
CHX: 102172215(PUM1) 102174942(PUM2)
OAS: 101103795(PUM2) 101120896(PUM1)
ODA: 120851907(PUM2) 120854179(PUM1)
CCAD: 122426784(PUM1) 122442029(PUM2)
SSC: 100517038(PUM1) 100523902(PUM2)
CFR: 102518175(PUM2) 102521453(PUM1)
CBAI: 105062951(PUM2) 105066790(PUM1)
CDK: 105085818(PUM1) 105095721(PUM2)
VPC: 102530662(PUM2) 102543827(PUM1)
BACU: 103010627(PUM1) 103010972(PUM2)
LVE: 103070337(PUM1) 103072151(PUM2)
OOR: 101279372(PUM1) 101282237(PUM2)
DLE: 111175036(PUM2) 111175485(PUM1)
PCAD: 102985712(PUM1) 102986156(PUM2)
PSIU: 116747374(PUM1) 116763941(PUM2)
ECB: 100056370(PUM2) 100070514(PUM1)
EPZ: 103545069 103562209(PUM2) 103566174(PUM1)
EAI: 106829075(PUM1) 106835579(PUM2)
MYB: 102241768(PUM1) 102250343(PUM2)
MYD: 102763902(PUM2) 102771316(PUM1)
MMYO: 118669242(PUM2) 118676313(PUM1)
MLF: 102422886(PUM2) 102436619(PUM1)
MNA: 107540422(PUM1) 107546380(PUM2)
PKL: 118717071(PUM2) 118723862(PUM1)
HAI: 109388124(PUM2) 109391999(PUM1)
DRO: 112297738(PUM2) 112299293(PUM1)
SHON: 118979428(PUM2) 118994572(PUM1)
AJM: 119052269(PUM1) 119053998(PUM2)
PDIC: 114497185(PUM1) 114499792(PUM2)
PHAS: 123822446(PUM2) 123831606(PUM1)
MMF: 118626537(PUM1) 118630778(PUM2)
RFQ: 117026753(PUM1) 117032683(PUM2)
PALE: 102881371(PUM2) 102881608(PUM1)
PGIG: 120599602(PUM1) 120621918(PUM2)
PVP: 105289782(PUM2) 105290552(PUM1)
RAY: 107503533(PUM1) 107510834(PUM2)
MJV: 108385062(PUM1) 108389758 108401219(PUM2)
TOD: 119235376(PUM1) 119259519(PUM2)
SARA: 101548815(PUM1) 101555113(PUM2)
LAV: 100662019(PUM1) 100671660(PUM2)
DNM: 101437932(PUM2) 101438906(PUM1)
MDO: 100015324(PUM2) 100027072(PUM1)
GAS: 123236640(PUM2) 123240413(PUM1)
SHR: 100918981(PUM1) 100919997(PUM2)
PCW: 110194847(PUM2) 110206198(PUM1)
OAA: 100085432(PUM2) 100086863(PUM1)
GGA: 419554(PUM1) 421961(PUM2)
PCOC: 116230144(PUM1) 116240555(PUM2)
MGP: 100539940 100541749(PUM2)
CJO: 107312251(PUM2) 107323966(PUM1)
NMEL: 110387265(PUM1) 110397167(PUM2)
APLA: 101792623(PUM1) 101804988
ACYG: 106044668(PUM2) 106045136(PUM1)
AFUL: 116488220(PUM2) 116498006(PUM1)
TGU: 100222720(PUM2) 100222835(PUM1)
LSR: 110467920(PUM2) 110469534(PUM1)
SCAN: 103820804(PUM2) 103822615(PUM1)
PMOA: 120508267(PUM2) 120511686(PUM1)
OTC: 121342808(PUM1) 121345279(PUM2)
PRUF: 121359923(PUM1) 121360746(PUM2)
GFR: 102038636(PUM1) 102044451(PUM2)
FAB: 101806646(PUM1) 101815913(PUM2)
PHI: 102100175(PUM2) 102114509(PUM1)
PMAJ: 107201643(PUM2) 107214062
CCAE: 111925998(PUM2) 111938947(PUM1)
CCW: 104685412(PUM2) 104697718(PUM1)
ETL: 114064999(PUM2) 114070257(PUM1)
ZAB: 102063302(PUM2)
FPG: 101917920(PUM1) 101923211(PUM2)
FCH: 102056882(PUM1) 102058131(PUM2)
CLV: 102092248(PUM2) 102095586(PUM1)
EGZ: 104129582(PUM2) 104132533(PUM1)
NNI: 104014638(PUM2) 104015699(PUM1)
ACUN: 113477609(PUM2) 113488193(PUM1)
TALA: 104362464(PUM2) 104369298(PUM1)
PADL: 103915438(PUM1) 103922164(PUM2)
ACHC: 115350850(PUM2) 115351548(PUM1)
AAM: 106487688(PUM2) 106491129(PUM1)
AROW: 112966535(PUM2) 112971208(PUM1)
NPD: 112950948(PUM1) 112952097(PUM2)
DNE: 112981186(PUM1) 112993240(PUM2)
ASN: 102371760(PUM1) 102382330(PUM2)
AMJ: 102568016(PUM1) 102569706(PUM2)
CPOO: 109311614(PUM2) 109318650(PUM1)
GGN: 109293980(PUM1) 109300189(PUM2)
PSS: 102446405(PUM1) 102459134(PUM2)
CMY: 102930240(PUM2) 102935915(PUM1)
CPIC: 101944651(PUM2) 101950840(PUM1)
TST: 117868414(PUM1) 117875334(PUM2)
CABI: 116821173(PUM2) 116837644(PUM1)
MRV: 120389065(PUM1) 120400683(PUM2)
ACS: 100557072(pum2) 100558502(pum1)
PVT: 110074238(PUM2) 110089362(PUM1)
SUND: 121915682(PUM1) 121921947(PUM2)
PBI: 103055887(PUM2) 103057995(PUM1)
PMUR: 107293054(PUM1) 107294745(PUM2)
TSR: 106541004(PUM1) 106549060(PUM2)
PGUT: 117663472(PUM1) 117674270(PUM2)
VKO: 123026104(PUM1) 123030896(PUM2)
PMUA: 114593703(PUM2) 114603622(PUM1)
ZVI: 118082461(PUM2) 118086180(PUM1)
GJA: 107105452(PUM2) 107120644(PUM1)
XLA: 100653503(pum2.L) 108708085(pum1.L) 108718259(pum2.S) 394392(pum1.S)
XTR: 100137097(pum1) 100496617(pum2)
NPR: 108795616(PUM1) 108800903(PUM2)
RTEM: 120927389(PUM1) 120936299(PUM2)
BBUF: 120995243(PUM1) 120997336(PUM2)
BGAR: 122933127(PUM1) 122934224(PUM2)
DRE: 394176(pum1) 567494(pum2)
PPRM: 120485198(pum1) 120485897(pum2)
IPU: 108256953(pum1)
PHYP: 113536282(pum1)
SMEO: 124375940(pum1)
TFD: 113661484(pum1)
AMEX: 103033393(pum1)
EEE: 113588351(pum1)
TRU: 101071137(pum1) 101076824(pum2)
LCO: 104922077(pum1) 104926753(pum2)
NCC: 104943525 104947262(pum2)
CGOB: 115003555(pum2) 115015438(pum1)
ELY: 117263567(pum1) 117270509(pum2)
PLEP: 121957501(pum1)
SLUC: 116066414(pum2) 116066867(pum1)
ECRA: 117956544(pum1) 117961572(pum2)
PFLV: 114568016(pum1) 114573262(pum2)
GAT: 120807765(pum2) 120826919(pum1)
PPUG: 119195135(pum2) 119219190(pum1)
MSAM: 119907388(pum1) 119908930(pum2)
CUD: 121521128(pum2) 121523687(pum1)
MZE: 101467055 101486682(pum1)
ONL: 100697243(pum1) 100701094(pum2)
OAU: 116312026(pum1) 116324149(pum2)
OLA: 100335141(pum1) 100335142(pum2)
OML: 112158369(pum2) 112160495(pum1)
XMA: 102223040(pum2) 102237593(pum1)
XCO: 114155718(pum1) 114158194(pum2)
XHE: 116731140(pum1) 116734064(pum2)
PRET: 103457436(pum2) 103472315(pum1)
PFOR: 103134042(pum2) 103135199(pum1)
PLAI: 106953720(pum2) 106963089(pum1)
PMEI: 106911830(pum1) 106918139 106924037(pum2)
GAF: 122825764(pum2) 122843675(pum1)
CVG: 107081622(pum2) 107083277(pum1)
CTUL: 119779156(pum2) 119785874(pum1)
GMU: 124879349(pum1) 124881775(pum2)
NFU: 107377661(pum2) 107394787(pum1)
KMR: 108233440(pum2) 108241580(pum1)
ALIM: 106515756(pum1) 106534306
NWH: 119418568(pum2) 119425792(pum1)
AOCE: 111566437 111578370(pum1)
CSEM: 103380911(pum2) 103394344(pum1)
POV: 109631780(pum1) 109636098
SSEN: 122783954(pum2) 122786859(pum1)
HHIP: 117757963(pum2) 117770465(pum1)
LCF: 108895949(pum2) 108897760(pum1)
SDU: 111223539(pum1) 111237398(pum2)
SLAL: 111659298(pum1) 111661527(pum2)
XGL: 120786567(pum1) 120788851(pum2)
HCQ: 109516798 109518389(pum1)
BPEC: 110167532(pum1) 110173903(pum2)
MALB: 109952617(pum2) 109963969(pum1)
OGO: 123994839(pum2) 124012123(pum1) 124043159
ONE: 115107557(pum2) 115128613(pum1) 115139683
ELS: 105012432(pum1) 105015355(pum2)
SFM: 108921833(pum2) 108931800(pum1)
PKI: 111839722(pum1) 111855562(pum2)
LOC: 102695334(pum1) 102698873(pum2)
LCM: 102350804(PUM2) 102355467(PUM1)
CMK: 103179507(pum1) 103187477
BFO: 118404614
BBEL: 109473002
CIN: 100186555
SCLV: 120330952
SPU: 589897
APLC: 110989498
DME: Dmel_CG9755(pum)
DER: 6552418
DSE: 6607153
DSI: Dsimw501_GD20817(Dsim_GD20817)
DAN: 6501200
DSR: 110186892
DPE: 6592084
DMN: 108154994
DWI: 6651611
DAZ: 108611960
DNV: 108656315
DHE: 111593611
CCAT: 101452271
BOD: 106624297
MDE: 101893967
SCAC: 106081092
LCQ: 111690812
ACOZ: 120953846
AARA: 120897497
AAG: 5576263
CPII: 120417494
CNS: 116342667
AME: 408298
ACER: 107999505
ALAB: 122712092
BIM: 100742170
BBIF: 117214413
BVK: 117232141
BVAN: 117156155
BTER: 100648330
BPYO: 122571429
CCAL: 108627225
OBB: 114877308
MGEN: 117220005
NMEA: 116428416
CGIG: 122399823
SOC: 105199367
MPHA: 105835291
AEC: 105153390
ACEP: 105619498
PBAR: 105425244
VEM: 105566474
HST: 105180737
DQU: 106742304
CFO: 105247760
FEX: 115237251
LHU: 105678527
PGC: 109858586
OBO: 105287670
PCF: 106784094
PFUC: 122521309
VPS: 122626930
NVI: 100123444
CSOL: 105362863
TPRE: 106660588
MDL: 103577311
CGLO: 123275259
FAS: 105270348
DAM: 107036062
AGIF: 122853159
CCIN: 107272364
TCA: 656229(FBF)
DPA: 109542731
SOY: 115878934
CSET: 123311230
AGB: 108903762
LDC: 111517713
NVL: 108569394
APLN: 108735761
PPYR: 116164808
OTU: 111427820
BMOR: 101742087
BMAN: 114250200
MSEX: 115442084
BANY: 112058060
PMAC: 106707858
PPOT: 106111001
PXU: 106118228
PRAP: 110995261
ZCE: 119830263
HAW: 110370345
TNL: 113492886
SLIU: 111354567
OFU: 114355717
PXY: 105381096
API: 100159140
DNX: 107173099
AGS: 114121075
RMD: 113555015
BTAB: 109041486
CLEC: 106663606
HHAL: 106683111
NLU: 111046922
FOC: 113209678
ZNE: 110828773
CSEC: 111871638
FCD: 110844177
DMK: 116917708
PJA: 122246322
PCHN: 125036318
HAME: 121870991
PCLA: 123774781
PTRU: 123510614
HAZT: 108670395
DSV: 119450094
RSAN: 119383307
RMP: 119170295
TUT: 107362305
DPTE: 113792115
DFR: 124489956
CSCU: 111632486
PTEP: 107454202
SDM: 118200674
CEL: CELE_W06B11.2(puf-9)
CBR: CBG_14762(Cbr-puf-9)
BMY: BM_BM6207(Bm6207)
TSP: Tsp_04240
PCAN: 112561603
BGT: 106055561
GAE: 121376823
HRF: 124131644
HRJ: 124286297
CRG: 105325164
MYI: 110464154
PMAX: 117316178
MMER: 123540191
OBI: 106874486
OSN: 115223619
EGL: EGR_02486
NVE: 5514691
EPA: 110246476
ATEN: 116301530
ADF: 107331726
AMIL: 114948306
PDAM: 113678685
SPIS: 111328056
DGT: 114525056
XEN: 124455658
HMG: 100200828
AQU: 100634056
ATH: AT2G29140(PUM3) AT2G29190(PUM2) AT2G29200(PUM1) AT3G10360(PUM4) AT3G20250(PUM5) AT4G25880(PUM6)
LJA: Lj0g3v0047679.1(Lj0g3v0047679.1) Lj0g3v0152859.1(Lj0g3v0152859.1) Lj0g3v0152859.2(Lj0g3v0152859.2) Lj0g3v0219909.1(Lj0g3v0219909.1) Lj0g3v0219909.2(Lj0g3v0219909.2) Lj0g3v0219909.3(Lj0g3v0219909.3) Lj0g3v0254439.1(Lj0g3v0254439.1) Lj2g3v2624100.1(Lj2g3v2624100.1) Lj4g3v2122820.1(Lj4g3v2122820.1) Lj5g3v1806980.1(Lj5g3v1806980.1) Lj5g3v1806980.2(Lj5g3v1806980.2) Lj6g3v1356520.1(Lj6g3v1356520.1)
DOSA: Os01t0844800-01(Os01g0844800) Os01t0971900-01(Os01g0971900) Os02t0819300-01(Os02g0819300) Os04t0201200-01(Os04g0201200) Os05t0109600-01(Os05g0109600) Os08t0519800-01(Os08g0519800) Os09t0497100-01(Os09g0497100) Os12t0574400-01(Os12g0574400)
MNG: MNEG_7013
SPO: SPAC1687.22c(puf3)
ABP: AGABI1DRAFT110884(AGABI1DRAFT_110884) AGABI1DRAFT53014(AGABI1DRAFT_53014)
ABV: AGABI2DRAFT199387(AGABI2DRAFT_199387) AGABI2DRAFT213339(AGABI2DRAFT_213339)
DDI: DDB_G0279735(pufA)
DFA: DFA_12331(pufA)
EHI: EHI_147880(142.t00014)
PCB: PCHAS_072820(PC000579.01.0) PCHAS_123410(PC000021.03.0)
TAN: TA07515
TPV: TP04_0263
BBO: BBOV_II003300(18.m06278)
SMIN: v1.2.002799.t1(symbB.v1.2.002799.t1) v1.2.006596.t1(symbB.v1.2.006596.t1) v1.2.007791.t1(symbB.v1.2.007791.t1) v1.2.012057.t1(symbB.v1.2.012057.t1) v1.2.013064.t1(symbB.v1.2.013064.t1) v1.2.016123.t1(symbB.v1.2.016123.t1) v1.2.017847.t1(symbB.v1.2.017847.t1) v1.2.022329.t1(symbB.v1.2.022329.t1) v1.2.023271.t1(symbB.v1.2.023271.t1) v1.2.023272.t1(symbB.v1.2.023272.t1) v1.2.024025.t1(symbB.v1.2.024025.t1) v1.2.025649.t1(symbB.v1.2.025649.t1) v1.2.032380.t1(symbB.v1.2.032380.t1) v1.2.032380.t2(symbB.v1.2.032380.t2) v1.2.032983.t1(symbB.v1.2.032983.t1) v1.2.032983.t2(symbB.v1.2.032983.t2) v1.2.033353.t1(symbB.v1.2.033353.t1) v1.2.034390.t1(symbB.v1.2.034390.t1) v1.2.035486.t1(symbB.v1.2.035486.t1) v1.2.038994.t1(symbB.v1.2.038994.t1)
SPAR: SPRG_18907
TCR: 510125.10
LMA: LMJF_33_1150(PUF6)
LIF: LINJ_33_1210(PUF6)
LBZ: LBRM_33_1360(PUF6)
LPAN: LPMP_331210(PUF6)
 » show all
Reference
  Authors
Morris AR, Mukherjee N, Keene JD
  Title
Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets.
  Journal
Mol Cell Biol 28:4093-103 (2008)
DOI:10.1128/MCB.00155-08
  Sequence
[hsa:9698] [dme:Dmel_CG9755]
Reference
  Authors
Spassov DS, Jurecic R
  Title
The PUF family of RNA-binding proteins: does evolutionarily conserved structure equal conserved function?
  Journal
IUBMB Life 55:359-66 (2003)
DOI:10.1080/15216540310001603093
  Sequence
[hsa:9698]
Reference
  Authors
Van Etten J, Schagat TL, Hrit J, Weidmann CA, Brumbaugh J, Coon JJ, Goldstrohm AC
  Title
Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.
  Journal
J Biol Chem 287:36370-83 (2012)
DOI:10.1074/jbc.M112.373522
  Sequence
[hsa:9698 23369]
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