KEGG   ORTHOLOGY: K18231
Entry
K18231                      KO                                     
Symbol
msr, vmlR
Name
macrolide transport system ATP-binding/permease protein
Pathway
map02010  ABC transporters
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
   01504 Antimicrobial resistance genes
    K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  Other subfamilies
   Macrolide exporter
    K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Macrolide resistance genes
   Transporters
    K18231  msr, vmlR; macrolide transport system ATP-binding/permease protein
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18231
Other DBs
COG: COG0488
TC: 3.A.1.121.1 3.A.1.121.3 3.A.1.121.6
Genes
ECLE: ECNIH2_24625
KPZ: KPNIH27_26435
KPX: PMK1_ndm00230(yheS)
KOE: A225_R1p0475 A225_R1p0735
KOK: KONIH1_31210
CFD: CFNIH1_25730
CFQ: C2U38_21270(msr)
CSED: JY391_23255(msr(E))
CIE: AN232_27590
EBC: C2U52_01360(msr)
PMP: Pmu_03460(msr(E))
BTO: WQG_1100
BTRH: F543_22760
ABH: M3Q_2654
ATG: J4G44_13270(msr(E)) J4G44_13460
AEA: C2U39_23915(msr)
BSU: BSU05610(vmlR)
BSR: I33_0645
BSL: A7A1_1364
BSH: BSU6051_05610(vmlR)
BSUT: BSUB_00619(vmlR)
BSUL: BSUA_00619(vmlR)
BSO: BSNT_06923(expZ)
BSQ: B657_05610(vmlR)
BSX: C663_0545(expZ)
BSS: BSUW23_02860(vmlR)
BST: GYO_0813
BLI: BL00895(expZ)
BLD: BLi02182(expZ)
BAY: RBAM_005960(abc-f)
BAQ: BACAU_0513(expZ)
BYA: BANAU_0516(expZ)
BAMP: B938_02735
BQY: MUS_0565(expZ)
BAML: BAM5036_0523(vmlR)
BAMA: RBAU_0555(vmlR)
BAMN: BASU_0544(vmlR)
BAMB: BAPNAU_0522(expZ)
BAMT: AJ82_03330
BAMY: V529_05250(expZ)
BMP: NG74_00572(yheS_1)
BAO: BAMF_0495(vmlR)
BAZ: BAMTA208_02570(vmlR)
BQL: LL3_00528(vmlR)
BXH: BAXH7_00538(expZ)
BAMI: KSO_016765
BAMC: U471_05710
BAMF: U722_02950
BMOJ: HC660_06000(vmlR)
BTEQ: G4P54_03070(vmlR)
BAN: BA_5409
BAR: GBAA_5409
BAI: BAA_5439
BANT: A16_54220
BANR: A16R_54860
BANV: DJ46_1382(ccmA) DJ46_4073
BCA: BCE_2620
BCZ: BCE33L2346(expZ) BCE33L4873(vba)
BCQ: BCQ_2476(expZ)
BCX: BCA_2689
BAL: BACI_c25790(expZ)
BNC: BCN_2472
BCF: bcf_13045
BTK: BT9727_2381(expZ) BT9727_4858(vba)
BTL: BALH_2339(expZ)
BTG: BTB_c26540(expZ1)
BTI: BTG_06725
BTW: BF38_3782(ccmA) BF38_907
BWW: bwei_2294(ccmA2) bwei_4615(vba)
BTRO: FJR70_06250(abc-f)
BNT: GSN03_13210(abc-f) GSN03_24610(abc-f)
BPAC: LMD38_01030(abc-f) LMD38_14080(abc-f)
BJS: MY9_0623
BACP: SB24_06880
BACB: OY17_05605
BACO: OXB_1076
BACY: QF06_01725
BACL: BS34A_06450(vmlR)
BALM: BsLM_0585
BGY: BGLY_2408
BBAD: K7T73_10960(abc-f)
BMQ: BMQ_2752(expZ)
BMD: BMD_2736(expZ)
BMH: BMWSH_2448(expZ)
PKS: IE339_14660(abc-f)
BHA: BH1900(expZ)
BCL: ABC3341
CGOT: J1899_01650(abc-f)
OIH: OB0699
ASED: IRT44_16955(vga)
LSP: Bsph_4456(expZ) Bsph_4526(msrA)
LPAK: GDS87_22630(abc-f)
LMAC: I6G82_20775(abc-f) I6G82_20985(abc-f)
TAID: KS242_09065(abc-f)
VPT: KBP50_16235(abc-f)
PASA: BAOM_1944
PPSR: I6J18_08305(abc-f)
PSYO: PB01_18535
PRD: F7984_13070(abc-f)
SCIB: HUG20_05055(abc-f)
SCIA: HUG15_06960(abc-f)
MEKU: HUW50_18105(abc-f) HUW50_21500(abc-f)
MSEM: GMB29_14915(abc-f)
MDG: K8L98_09900(abc-f)
BLEN: NCTC4824_02123(expZ)
SEDD: ERJ70_02875(abc-f)
BVQ: FHE72_03480(abc-f)
RMF: D5E69_18750(abc-f)
BVJ: I5776_18845(abc-f)
BOU: I5818_14510(abc-f)
SUZ: MS7_0047
SAUI: AZ30_14325
SHA: SH2305(msrSA)
SARL: SAP2_01610
JEA: JEM45_09880(abc-f)
LMO: lmo0919
LMOD: LMON_0926
LMOW: AX10_13160
LMOM: IJ09_05700
LMOG: BN389_09500(msrA)
LMP: MUO_04875
LMOZ: LM1816_16280(abc-f)
LMOX: AX24_01975
LMQ: LMM7_0956(uup)
LMS: LMLG_1408
LMOK: CQ02_04815
LMV: Y193_11150(abc-f)
LIN: lin0920
LWE: lwe0898
LSG: lse_0817
LIV: LIV_0861
LGZ: NCTC10812_02480(yjjK)
LMAR: LAX80_004210(abc-f)
EACE: KKI46_17040(msr(G))
GSA: FOC50_01610(msr)
BCHS: JNE38_00185(abc-f)
PLW: D5F53_12585(msr)
PRZ: GZH47_30165(abc-f)
PLYC: GXP70_17290(abc-f)
PCEL: HUB94_26780(abc-f)
ASOC: CB4_02665(yheS_2)
SIV: SSIL_2504
PDEC: H1Q58_01005(abc-f)
SPAE: E2C16_06795(abc-f)
PANC: E2636_16970(abc-f)
SNT: SPT_1925
SND: MYY_1872
SPNN: T308_09140
SSI: SSU1187
SUP: YYK_05665
SSUT: TL13_0643
SEZ: Sez_1888(msrA)
SEQ: SZO_18770
SEQU: Q426_09775
SEU: SEQ_2165
SDS: SDEG_1330 SDEG_2095(msrA)
SDA: GGS_1924(msrA)
SDC: SDSE_1551 SDSE_2198(msrA)
SDQ: SDSE167_2233(msrA)
STRN: SNAG_1038(yheS_1)
SPLR: C0J00_06460(msr)
SCAI: NCTC12191_00667(msrA_2)
SPOC: NCTC10925_01255(yheS_4)
SPAB: KQ224_02425(msr(D))
LAM: LA2_00135
LAE: LBAT_1630
LPL: lp_0215
LPJ: JDM1_0200
LPZ: Lp16_0195
LBR: LVIS_0105
CPAB: G6534_01120(abc-f)
WKO: WKK_04755
EFA: EF1413
EFL: EF62_1864
EFI: OG1RF_11201(msrA)
EFS: EFS1_1238
EFQ: DR75_486
EFM: M7W_2629
ECAS: ECBG_00224
EMU: EMQU_2574
EGV: EGCR1_03440(abc-f)
ELAC: I4Q40_12580(msr)
EIE: ENLAB_08240(uup_2)
TEY: GLW17_03470(abc-f)
CML: BN424_2976(Uup)
CARN: FPV25_03805(abc-f)
JEH: EJN90_08870(abc-f)
JPO: G7058_10370(abc-f)
CAC: CA_C3007
CAE: SMB_G3043(expZ)
CAY: CEA_G3013
CPE: CPE0784
CBY: CLM_0655
CBL: CLK_3763
CBK: CLL_A2014
CBB: CLD_0197
CBI: CLJ_B0634
CBT: CLH_1590
CBF: CLI_0632
CBM: CBF_0600
CPAS: Clopa_3740
CSQ: CSCA_2534
CFER: D4Z93_07765(abc-f)
CLOS: DMR38_09740(abc-f)
AMT: Amet_1903
AOE: Clos_0945
CTH: Cthe_2270
HSC: HVS_12735(yheS1)
RHER: EHE19_010165(abc-f)
BPB: bpr_I2869
BPRO: PMF13cell1_02308(yheS)
CPY: Cphy_1598
ANR: Ana3638_23795(msr)
PTH: PTH_1520(Uup)
DAE: Dtox_2791
VGU: HYG85_02690(abc-f)
VPY: HZI73_02350(abc-f)
ACAE: HYG86_05125(msr) HYG86_12145(abc-f)
FMA: FMG_1396
PHAR: NCTC13077_00266(yjjK_1)
KPAR: JL105_02265(abc-f)
PFT: JBW_03724
STED: SPTER_26830(yheS_1)
BEG: INE88_02665(msr(D))
AG: AAF91071(msr(C)) AAK69028(msr(D)) ABG33795(msr(E)) CAA36304(msr(A))
 » show all
Reference
  Authors
Reynolds E, Ross JI, Cove JH
  Title
Msr(A) and related macrolide/streptogramin resistance determinants: incomplete transporters?
  Journal
Int J Antimicrob Agents 22:228-36 (2003)
DOI:10.1016/S0924-8579(03)00218-8
Reference
PMID:2233255
  Authors
Ross JI, Eady EA, Cove JH, Cunliffe WJ, Baumberg S, Wootton JC
  Title
Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family.
  Journal
Mol Microbiol 4:1207-14 (1990)
DOI:10.1111/j.1365-2958.1990.tb00696.x
  Sequence
Reference
  Authors
Crowe-McAuliffe C, Graf M, Huter P, Takada H, Abdelshahid M, Novacek J, Murina V, Atkinson GC, Hauryliuk V, Wilson DN
  Title
Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR.
  Journal
Proc Natl Acad Sci U S A 115:8978-8983 (2018)
DOI:10.1073/pnas.1808535115
  Sequence
[bsu:BSU05610]
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