KEGG ORTHOLOGY: K18341

ORTHOLOGY: K18341

Entry

K18341                      KO

Symbol

TBC1D1

Name

TBC1 domain family member 1

Pathway

map04152

AMPK signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K18341  TBC1D1; TBC1 domain family member 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K18341  TBC1D1; TBC1 domain family member 1
Membrane trafficking [BR:ko04131]
Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    K18341  TBC1D1; TBC1 domain family member 1
Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    K18341  TBC1D1; TBC1 domain family member 1
Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab associated proteins
    K18341  TBC1D1; TBC1 domain family member 1

Other DBs

GO:	0005096 0017137

TC:	8.A.87.1.4

Genes

HSA:	23216(TBC1D1)

PTR:	461163(TBC1D1)

PPS:	100994615(TBC1D1)

GGO:	101131914(TBC1D1) 129526106 129526873 134756953

PON:	100453546(TBC1D1)

PPYG:

129034827(TBC1D1)

NLE:	100601007(TBC1D1)

HMH:	116457096(TBC1D1)

SSYN:

129464874(TBC1D1)

MCC:	697357(TBC1D1)

MCF:	101925340(TBC1D1)

MTHB:

126954886

MNI:	105487750(TBC1D1)

CSAB:

103246222(TBC1D1)

CATY:

105584867(TBC1D1)

PANU:

101026070(TBC1D1)

TGE:	112624467(TBC1D1)

MLEU:

105542132(TBC1D1)

RRO:	104664348(TBC1D1)

RBB:	108536745(TBC1D1)

TFN:	117085265(TBC1D1)

PTEH:

111550905(TBC1D1)

CANG:

105516792(TBC1D1)

CJC:	100393136(TBC1D1)

SBQ:	101031668(TBC1D1)

CIMI:

108303418(TBC1D1)

ANAN:

105732727(TBC1D1)

MMUR:

105874853(TBC1D1)

LCAT:

123637361(TBC1D1)

PCOQ:

105810505(TBC1D1)

OGA:	100956662(TBC1D1)

MMU:	57915(Tbc1d1)

MCAL:

110294134(Tbc1d1)

MPAH:

110330392(Tbc1d1)

RNO:	360937(Tbc1d1)

MCOC:

116071012(Tbc1d1)

ANU:	117712760(Tbc1d1)

ASYL:

127696589(Tbc1d1)

MUN:	110554837(Tbc1d1)

CGE:

100755731

MAUA:

101830787(Tbc1d1)

PROB:

127213587(Tbc1d1)

PLEU:

114692411(Tbc1d1)

MORG:

121460741(Tbc1d1)

MFOT:

126506315

AAMP:

119824281(Tbc1d1)

NGI:	103734350(Tbc1d1)

HGL:	101713688(Tbc1d1)

CPOC:

100713383(Tbc1d1)

CCAN:

109685158(Tbc1d1)

DORD:

105980279(Tbc1d1)

DSP:	122106901(Tbc1d1)

PLOP:

125364755(Tbc1d1)

NCAR:

124994430

MMMA:

107139175(Tbc1d1)

ITI:	101978641(Tbc1d1)

OCU:

100352741

OPI:	101525885(TBC1D1)

TUP:	102495320(TBC1D1)

GVR:	103597784(TBC1D1)

CFA:	479115(TBC1D1)

CLUD:

112653755(TBC1D1)

VVP:	112919215(TBC1D1)

VLG:	121490015(TBC1D1)

NPO:	129510399(TBC1D1)

AML:	100469773(TBC1D1)

UMR:	103672659(TBC1D1)

UAH:	113262401(TBC1D1)

UAR:	123804281(TBC1D1)

ELK:

111149365

LLV:

125093627

MPUF:

101677902(TBC1D1)

MNP:	132005321(TBC1D1)

MLK:	131824963(TBC1D1)

NVS:	122889511(TBC1D1)

ORO:	101363971(TBC1D1)

EJU:	114198654(TBC1D1)

ZCA:	113924369(TBC1D1)

MLX:	118010622(TBC1D1)

NSU:	110590739(TBC1D1)

LWW:	102737463(TBC1D1)

FCA:	101086057(TBC1D1)

PYU:	121037030(TBC1D1)

PCOO:

112859047(TBC1D1)

PBG:	122478955(TBC1D1)

PVIV:

125163629(TBC1D1)

LRUF:

124520227

LGF:	123596075(TBC1D1)

AJU:

106979166

PTG:	102953971(TBC1D1)

PPAD:

109246407(TBC1D1)

PUC:

125922702

PLEZ:

122218324(TBC1D1)

HHV:	120228554(TBC1D1)

BTA:	282704(TBC1D1)

BOM:	102281547(TBC1D1)

BIU:	109560394(TBC1D1)

BBUB:

102408743(TBC1D1)

BBIS:

104997574(TBC1D1)

CHX:	102189380(TBC1D1)

OAS:	101111550(TBC1D1)

BTAX:

128049408(TBC1D1)

CSUM:

138082121(TBC1D1)

ODA:	120862028(TBC1D1)

CCAD:

122421984(TBC1D1)

MREE:

136148125(TBC1D1)

OVR:	110145247(TBC1D1)

MBEZ:

129562002(TBC1D1)

SSC:	100524447(TBC1D1)

CFR:	102518400(TBC1D1)

CBAI:

105074963(TBC1D1)

CDK:	105089350(TBC1D1)

VPC:	102538515(TBC1D1)

BACU:

102999541(TBC1D1)

BMUS:

118895545(TBC1D1)

LVE:	103089224(TBC1D1)

OOR:	101270851(TBC1D1)

LALB:

132519907(TBC1D1)

DLE:	111170679(TBC1D1)

PCAD:

102984927(TBC1D1)

PSIU:

116754116(TBC1D1)

NASI:

112390619(TBC1D1)

ECB:	100055336(TBC1D1)

EPZ:	103552803(TBC1D1)

EAI:	106831099(TBC1D1)

MYB:	102251384(TBC1D1)

MYD:	102771902(TBC1D1)

MMYO:

118667567(TBC1D1)

MLF:	102424912(TBC1D1)

MDT:	132220385(TBC1D1)

MYUM:

138996816(TBC1D1)

PKL:	118707838(TBC1D1)

EFUS:

103284900(TBC1D1)

MNA:	107532109(TBC1D1)

DRO:	112316794(TBC1D1)

SHON:

118999650(TBC1D1)

AJM:	119045609(TBC1D1)

PDIC:

114492690(TBC1D1)

PHAS:

123815706(TBC1D1)

MMF:	118631544(TBC1D1)

PPAM:

129077576(TBC1D1)

HAI:	109379475(TBC1D1)

RFQ:	117022226(TBC1D1)

PALE:

102895605(TBC1D1)

PGIG:

120591197(TBC1D1)

PVP:	105295814(TBC1D1)

RAY:	107508728(TBC1D1)

MJV:	108392547(TBC1D1)

TOD:	119260620(TBC1D1)

SARA:

101549892(TBC1D1)

SFUM:

130033953(TBC1D1)

SETR:

126032428(TBC1D1)

LAV:	100671373(TBC1D1)

TMU:

101358956

ETF:	101638268(TBC1D1)

DNM:

101424159

MDO:	100022584(TBC1D1)

GAS:	123252020(TBC1D1)

SHR:	100923630(TBC1D1)

AFZ:

127540820

PCW:	110212072(TBC1D1)

TVP:	118853129(TBC1D1)

PBRV:

138146560(TBC1D1)

OAA:	100082442(TBC1D1)

TACU:

119933209(TBC1D1)

GGA:	426162(TBC1D1)

PCOC:

116225849(TBC1D1)

MGP:	100538627(TBC1D1)

CJO:	107313825(TBC1D1)

TPAI:

128080754(TBC1D1)

LMUT:

125691564(TBC1D1)

NMEL:

110397318(TBC1D1)

APLA:

101790055(TBC1D1)

ACYG:

106039101(TBC1D1)

CATA:

118252155(TBC1D1)

AFUL:

116488508(TBC1D1)

TGU:	100227625(TBC1D1)

LSR:	110472000(TBC1D1)

SCAN:

103824729(TBC1D1)

PMOA:

120497392(TBC1D1)

PRUF:

121348740(TBC1D1)

ATRC:

139592525(TBC1D1)

GFR:	102036618(TBC1D1)

FAB:	101818379(TBC1D1)

OMA:	130252313(TBC1D1)

PHI:	102108560(TBC1D1)

PMAJ:

107203015(TBC1D1)

CCAE:

111928108(TBC1D1)

CCW:	104690682(TBC1D1)

CBRC:

103622426(TBC1D1)

ACOE:

138109907(TBC1D1)

ETL:	114059736(TBC1D1)

ZAB:	102073369(TBC1D1)

ZLE:	135446474(TBC1D1)

ACHL:

103805765(TBC1D1)

SVG:	106850020(TBC1D1)

MMEA:

130576766(TBC1D1)

HRT:	120752618(TBC1D1)

SATI:

136360125(TBC1D1)

CCIC:

134044295(TBC1D1)

FPG:	101914718(TBC1D1)

FCH:	102054780(TBC1D1)

CCRI:

104156416(TBC1D1)

NNT:	104402116(TBC1D1)

SHAB:

115610528(TBC1D1)

ACUN:

113479240(TBC1D1)

TALA:

104361403(TBC1D1)

ACHC:

115344073(TBC1D1)

HLE:	104836087(TBC1D1)

AGEN:

126053242

HHAR:

128138781(TBC1D1)

GCL:

127015901

CSTI:

104561121(TBC1D1)

LDI:	104345900(TBC1D1)

MNB:

103770790

DPUB:

104296716(TBC1D1)

PPUS:

135178304(TBC1D1)

AVIT:

104276959(TBC1D1)

BRHI:

104497313(TBC1D1)

EGZ:	104128481(TBC1D1)

NNI:	104009813(TBC1D1)

PCRI:

104038991

PCAO:

104048666(TBC1D1)

PADL:

103914694(TBC1D1)

AFOR:

103899645(TBC1D1)

FGA:

104078404

CBOY:

140652555(TBC1D1)

CLV:	102097572(TBC1D1)

MUI:

104534324

PGUU:

104467170

PLET:

104621516(TBC1D1)

EHS:

104513875

CUCA:

104064269(TBC1D1)

BREG:

104637170

OHA:	104330318(TBC1D1)

ACAR:

104532596(TBC1D1)

CPEA:

104396291(TBC1D1)

CVF:	104288072(TBC1D1)

RTD:	128910739(TBC1D1)

CRID:

134515774(TBC1D1)

AAM:	106490155(TBC1D1)

AROW:

112976851(TBC1D1)

NPD:	112945806(TBC1D1)

TGT:	104573007(TBC1D1)

DNE:	112979417(TBC1D1)

SCAM:

104143073(TBC1D1)

ASN:	102388874(TBC1D1)

AMJ:	102557901(TBC1D1)

CPOO:

109322097(TBC1D1)

GGN:	109303835(TBC1D1)

PSS:	102462204(TBC1D1)

CMY:	102938473(TBC1D1)

CCAY:

125636068(TBC1D1)

DCC:	119854437(TBC1D1)

CPIC:

101936144(TBC1D1)

TST:	117877616(TBC1D1)

CABI:

116821804(TBC1D1)

MRV:	120406182(TBC1D1)

ACS:	100556335(tbc1d1)

ASAO:

132776325(TBC1D1)

PVT:	110075219(TBC1D1)

SUND:

121932003(TBC1D1)

PBI:	103049887(TBC1D1)

PMUR:

107299221(TBC1D1) 107300580

CTIG:

120309861(TBC1D1)

PGUT:

117659146(TBC1D1)

APRI:

131203553(TBC1D1)

PTEX:

113435793(TBC1D1)

NSS:	113417100(TBC1D1)

VKO:	123016936(TBC1D1)

PMUA:

114603842(TBC1D1)

PRAF:

128421360(TBC1D1)

ZVI:	118083452(TBC1D1)

HCG:	128326675(TBC1D1)

GJA:	107116506(TBC1D1)

STOW:

125440045(TBC1D1)

EMC:	129342036(TBC1D1)

XLA:	108698064 108706564(tbc1d1.S)

XTR:	733547(tbc1d1)

NPR:	108795906(TBC1D1)

RTEM:

120924278(TBC1D1)

BBUF:

120990278(TBC1D1)

BGAR:

122941077(TBC1D1)

DTC:	141075853(TBC1D1)

PWL:	138247642(TBC1D1)

MUO:	115461468(TBC1D1)

GSH:	117361930(TBC1D1)

DRE:	561193(tbc1d1)

SRX:	107746016 107754138

SANH:

107656363 107702353

SGH:	107591525(tbc1d1)

CCAR:

109060471 109080221

CAUA:

113044189 113107282 113107336

CGIB:

127948816 127964766

PTET:

122345676(tbc1d1)

LROH:

127166276(tbc1d1)

OMC:	131531668(tbc1d1)

PPRM:

120493248(tbc1d1)

RKG:	130089499(tbc1d1)

MAMB:

125272571(tbc1d1)

CIDE:

127522322

CERY:

137031707(tbc1d1)

MASI:

127443385 127444517

TROS:

130552484(tbc1d1)

TDW:	130438745(tbc1d1)

MANU:

129444764(tbc1d1)

PDAB:

135760933(tbc1d1)

IPU:

108260704

IFU:	128604474(tbc1d1)

PHYP:

113547357

SMEO:

124381411(tbc1d1)

TFD:	113635475(tbc1d1)

TVC:	132841960(tbc1d1)

CGAR:

128508543(tbc1d1)

NGRA:

132883280(tbc1d1)

TRN:	134327099(tbc1d1)

AMEX:

103040408(tbc1d1)

CMAO:

118817066(tbc1d1)

EEE:	113587664(tbc1d1)

CHAR:

105903571(tbc1d1)

SPIL:

134059696(tbc1d1)

TRU:	101072432(tbc1d1)

TFS:	130526976(tbc1d1)

LCO:	104927666(tbc1d1)

NCC:	104951415(tbc1d1)

TBEN:

117474608(tbc1d1)

CGOB:

115008494(tbc1d1)

PGEO:

117445299(tbc1d1)

GACU:

117543373(tbc1d1)

EMAC:

134864794(tbc1d1)

ELY:	117255447(tbc1d1)

EFO:	125886438(tbc1d1)

PLEP:

121941933(tbc1d1)

SLUC:

116040451(tbc1d1)

ECRA:

117935635(tbc1d1)

ESP:	116706474(tbc1d1)

PFLV:

114565547(tbc1d1)

GAT:	120825591(tbc1d1)

PPUG:

119217792(tbc1d1)

AFB:	129095597(tbc1d1)

CLUM:

117735317(tbc1d1)

PSWI:

130190782(tbc1d1)

CANA:

137794841(tbc1d1)

CVE:	137868580(tbc1d1)

MSAM:

119899086(tbc1d1)

SCHU:

122873878(tbc1d1)

CUD:	121508232(tbc1d1)

SPUL:

138594826(tbc1d1)

LMIX:

132994703(tbc1d1)

ALAT:

119028335(tbc1d1)

ASTR:

137599766(tbc1d1)

MZE:

101473749

ONL:

100690481

OAU:	116311135(tbc1d1)

OLA:	101170401(tbc1d1)

OML:	112157015(tbc1d1)

CSAI:

133421265(tbc1d1)

XMA:	102222624(tbc1d1)

XCO:	114145624(tbc1d1)

XHE:	116720450(tbc1d1)

PRET:

103466719(tbc1d1)

PFOR:

103137925(tbc1d1)

PLAI:

106947396(tbc1d1)

PMEI:

106914234(tbc1d1)

GAF:	122829834(tbc1d1)

CVG:	107085729(tbc1d1)

CTUL:

119794218(tbc1d1)

GMU:	124868341(tbc1d1)

NFU:

107382155

KMR:	108230439(tbc1d1)

ALIM:

106520928(tbc1d1)

NWH:	119430784(tbc1d1)

AOCE:

111567852(tbc1d1)

EJA:	138208965(tbc1d1)

BFRE:

138620339(tbc1d1)

MCEP:

125004323(tbc1d1)

CSEM:

103383709(tbc1d1)

POV:

109638414

SSEN:

122771149(tbc1d1)

SSOE:

131466913(tbc1d1)

HHIP:

117766616(tbc1d1)

HSP:	118100531(tbc1d1)

PPLT:

128431305(tbc1d1)

SMAU:

118312051(tbc1d1)

LCF:

108896550

SDU:	111231427(tbc1d1)

SLAL:

111664045(tbc1d1)

XGL:	120800095(tbc1d1)

HCQ:	109519853(tbc1d1)

SSCV:

125968548(tbc1d1)

SBIA:

133505794(tbc1d1)

PEE:	133403820(tbc1d1)

PTAO:

133477025(tbc1d1)

BPEC:

110165315(tbc1d1)

ENY:	140377663(tbc1d1)

MALB:

109974149(tbc1d1)

BSPL:

114856844(tbc1d1)

SJO:	128377102(tbc1d1)

SSCO:

133995994(tbc1d1)

GMH:

115540301

OTW:	112242127 121845926(tbc1d1)

OMY:	110518842 118936694

OKI:

116362653

OKE:

127927321

OMM:	135535836 135535840

OCLA:

139394303 139394416

CCLU:

121563087(tbc1d1) 121564810

ELS:	109615182(tbc1d1)

OEP:	134034306(tbc1d1)

SFM:	108925754 108930843

PKI:	111833259 111853059(tbc1d1)

AANG:

118227773(tbc1d1)

AROT:

135254379(tbc1d1)

CCOG:

133130324(tbc1d1)

LOC:	102695652(tbc1d1)

PSPA:

121323871 121329177

ARUT:

117409086 117421240

PSEX:

120527645(tbc1d1)

LCM:

102366063

CMK:	103175849(tbc1d1)

RTP:	109933568(tbc1d1)

CPLA:

122551368(tbc1d1)

HOC:	132815782(tbc1d1)

LERI:

129698577(tbc1d1)

PMRN:

116943024

LRJ:	133343059(TBC1D1)

LPIC:

AJJ:

AFIL:

FCD:

EAF:

CVS:	136981937 136987871

ABRU:

UDV:

SDM:

LPOL:

BGT:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

LLON:

XEN:

HSY:

Reference

PMID:21250943

Authors

Fukuda M

Title

TBC proteins: GAPs for mammalian small GTPase Rab?

Journal

Biosci Rep 31:159-68 (2011)
DOI:10.1042/BSR20100112

Reference

PMID:16893906

Authors

Stone S, Abkevich V, Russell DL, Riley R, Timms K, Tran T, Trem D, Frank D, Jammulapati S, Neff CD, Iliev D, Gress R, He G, Frech GC, Adams TD, Skolnick MH, Lanchbury JS, Gutin A, Hunt SC, Shattuck D

Title

TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.

Journal

Hum Mol Genet 15:2709-20 (2006)
DOI:10.1093/hmg/ddl204

Sequence

[hsa:23216]

LinkDB

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