| Entry |
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| Name |
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| Definition |
dihydrofolate reductase (trimethoprim resistance protein) [EC: 1.5.1.3]
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K18591 dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
00670 One carbon pool by folate
K18591 dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes
K18591 dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
Enzymes [BR:ko01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
K18591 dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance genes [BR:ko01504]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
K18591 dfrD, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Kadlec K, Schwarz S |
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| Title |
Identification of a novel trimethoprim resistance gene, dfrK, in a methicillin-resistant Staphylococcus aureus ST398 strain and its physical linkage to the tetracycline resistance gene tet(L). |
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| Journal |
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| Reference |
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Roberts MC, Schwarz S, Aarts HJ |
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Erratum: Acquired antibiotic resistance genes: an overview. |
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| Reference |
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| Authors |
Skold O |
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| Title |
Resistance to trimethoprim and sulfonamides. |
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| LinkDB |
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